Noninvasive assessment of breast cancer risk using time-resolved diffuse optical spectroscopy

• Published in: Journal of Biomedical Optics Vol. 15; no. 6; p. 060501
• Main Authors: Taroni, Paola, Pifferi, Antonio, Quarto, Giovanna, Spinelli, Lorenzo, Torricelli, Alessandro, Abbate, Francesca, Villa, Anna M, Balestreri, Nicola, Menna, Simona, Cassano, Enrico, Cubeddu, Rinaldo
• Format: Journal Article
• Language: English
• Published: United States 01.11.2010
• Subjects: Assessments; Breast; Breast - physiopathology; Breast Neoplasms - diagnosis; Breast Neoplasms - physiopathology; Cancer; Collagens; Densitometry - instrumentation; Density; Diagnosis, Computer-Assisted - methods; Equipment Design; Equipment Failure Analysis; Estimates; Female; Humans; Middle Aged; Optical Devices; Reproducibility of Results; Risk; Risk Assessment; Sensitivity and Specificity; Spectroscopy; Spectrum Analysis - instrumentation

Breast density is a recognized strong and independent risk factor for breast cancer. We propose the use of time-resolved transmittance spectroscopy to estimate breast tissue density and potentially provide even more direct information on breast cancer risk. Time-resolved optical mammography at seven...