An Overview of Comet Assay Application for Detecting DNA Damage in Aquatic Animals

• Published in: Agriculture (Basel) Vol. 13; no. 3; p. 623
• Main Authors: Jiang, Nan, Naz, Saima, Ma, Yulin, Ullah, Qudrat, Khan, Muhammad Zahoor, Wang, Jiaqi, Lu, Xuan, Luosang, Dun-Zhu, Tabassum, Sadia, Chatha, Ahmad Manan Mustafa, Basang, Wang-Dui
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 01.03.2023
• Subjects: agriculture; Animals; Aquatic animals; Aquatic environment; Bioassays; Biocompatibility; Biodiversity; Cell culture; Comet assay; Damage detection; Deoxyribonucleic acid; digestion; DNA; DNA damage; DNA strand breakage; Endonuclease; Environmental impact; Environmental studies; Enzymes; Genotoxicity; Germ cells; habitats; Health risks; Heavy metals; In vivo methods and tests; Indicator species; Indicators (Biology); Industrial areas; Laboratories; Lesions; mutagens; National libraries; nontarget organisms; Nucleoids; Pesticides; Phytochemicals; Pollutants; SCGE assay; Toxic substances; Toxicity; Toxicology; Wildlife conservation; Workshops; United States > US

This review discusses several research studies that employed comet assay to evaluate the environmental impact of genotoxins in aquatic environments. It focuses on in vivo and in situ studies of aquatic animals. New chemicals are being added each year to the existing burden of toxic substances in the...