Association of Klotho with Coronary Artery Disease in Subjects with Type 2 Diabetes Mellitus and Preserved Kidney Function: A Case-Control Study

• Published in: International journal of molecular sciences Vol. 24; no. 17; p. 13456
• Main Authors: Donate-Correa, Javier, Martín-Núñez, Ernesto, Mora-Fernández, Carmen, González-Luis, Ainhoa, Martín-Olivera, Alberto, Navarro-González, Juan F.
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 01.09.2023; MDPI
• Subjects: Analysis; Atherosclerosis; Body mass index; Cardiovascular disease; Coronary heart disease; Coronary vessels; Development and progression; Diabetes; Diabetes therapy; Diabetics; Fibroblast growth factors; Kidney diseases; Kidneys; Longitudinal studies; Metabolic disorders; Mortality; Regression analysis; Signal transduction; Type 2 diabetes; Vein & artery diseases; Spain

Circulating Klotho levels are significantly reduced in subjects with type 2 diabetes mellitus (T2DM) and in kidney disease patients. In this work, the relationship between Klotho levels and the coronary artery disease (CAD) burden in subjects with T2DM and preserved kidney function was analyzed. For...