Controlled Human Infection and Rechallenge with Streptococcus pneumoniae Reveals the Protective Efficacy of Carriage in Healthy Adults - Ferreira, Daniela M.; Neill, Daniel R.; Bangert, Mathieu; Gritzfeld, Jenna F.; Green, Nicola; Wright, Adam K. A.; Pennington, Shaun H.; Moreno, Laura Bricio; Moreno, Adriana T.; Miyaji, Eliane N.; Wright, Angela D.; Collins, Andrea M.; et al. (American journal of respiratory and critical care medicine, 2013)
Keywords: Administration, Intranasal; Adult; Analysis of Variance; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Animals; Antibodies; Antibodies, Bacterial - blood; Antibodies, Bacterial - immunology; Bacterial diseases; Bacterial Proteins - immunology; Biological and medical sciences; Carrier State - immunology; Experiments; Female; Human bacterial diseases; Humans; Immunoglobulin G - analysis; Immunoglobulin G - blood; Immunology; Infectious diseases; Intensive care medicine; Male; Medical sciences; Mice; Nasal Lavage Fluid - immunology; Nasal Lavage Fluid - microbiology; Nasal Mucosa - immunology; Pneumococcal Infections - immunology; Pneumococcal Infections - prevention & control; Pneumology; Pneumonia; Proteins; Staphylococcal infections, streptococcal infections, pneumococcal infections; Streptococcus infections; Streptococcus pneumoniae - immunology; Vaccination - methods; Young Adult; United Kingdom--UK; Human; Intensive care; Respiratory disease; Immunity; Streptococcus pneumoniae; Infection; Prevention; Streptococcaceae; Efficiency; Streptococcal infection; Bacteriosis; Healthy carrier; Bacteria; Micrococcales; Adult; Models; Pneumococcal infection; human challenge models; Colonization; Resuscitation