The effect of coffee consumption on insulin sensitivity and other biological risk factors for type 2 diabetes: a randomized placebo-controlled trial
In observational studies, coffee consumption has been consistently associated with a lower risk of type 2 diabetes mellitus. Trials examining the effect of coffee consumption on glucose metabolism have been limited by the use of surrogate insulin sensitivity indices, small sample sizes, lack of blin...
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| Published in | The American journal of clinical nutrition Vol. 111; no. 2; pp. 448 - 458 |
|---|---|
| Main Authors | , , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
Elsevier Inc
01.02.2020
Oxford University Press American Society for Clinical Nutrition, Inc |
| Subjects | |
| Online Access | Get full text |
| ISSN | 0002-9165 1938-3207 1938-3207 |
| DOI | 10.1093/ajcn/nqz306 |
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| Abstract | In observational studies, coffee consumption has been consistently associated with a lower risk of type 2 diabetes mellitus. Trials examining the effect of coffee consumption on glucose metabolism have been limited by the use of surrogate insulin sensitivity indices, small sample sizes, lack of blinding, and short follow-up duration.
We aimed to overcome limitations of previously conducted coffee trials in a randomized placebo-controlled trial of the effect of coffee consumption on insulin sensitivity.
We conducted a 24-wk randomized placebo-controlled trial in 126 overweight, non–insulin sensitive (HOMA-IR ≥1.30), Chinese, Malay, and Asian-Indian males and females aged 35–69 y. Participants were randomly assigned to receive 4 cups of instant regular coffee (n = 62) or 4 cups of a coffee-like placebo beverage (n = 64) per day. The primary outcome was the amount of glucose metabolized per kilogram of body weight per minute (Mbw) assessed during steady-state conditions with a hyperinsulinemic euglycemic clamp. Secondary outcomes included other clamp-based insulin sensitivity measures, biological mediators of insulin sensitivity, and measures of fasting glucose metabolism.
Coffee consumption did not significantly change insulin sensitivity compared with placebo (percentage mean difference in Mbw = 4.0%; 95% CI: −8.3, 18.0%; P = 0.53). Furthermore, no significant differences in fasting plasma glucose (2.9%; 95% CI: −0.4, 6.3%; P = 0.09) or biological mediators of insulin resistance, such as plasma adiponectin (2.3%; 95% CI: −1.4, 6.2%; P = 0.22), were observed between coffee and placebo groups over 24 wk of intervention. Participants in the coffee arm experienced a loss of fat mass (FM) (−3.7%; 95% CI: −6.3, −1.1%; P = 0.006) and reduction in urinary creatinine concentrations (−21.2%; 95% CI: −31.4, −9.5%; P = 0.001) compared with participants in the placebo arm over 24 wk of intervention.
Consuming 4 cups/d of caffeinated coffee for 24 wk had no significant effect on insulin sensitivity or biological mediators of insulin resistance but was associated with a modest loss of FM and reduction in urinary creatinine concentrations. This trial was registered at clinicaltrials.gov as NCT01738399. Registered on November 28, 2012. Trial sponsor: Nestlé Research, Lausanne, Switzerland. Trial site: National University of Singapore. |
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| AbstractList | In observational studies, coffee consumption has been consistently associated with a lower risk of type 2 diabetes mellitus. Trials examining the effect of coffee consumption on glucose metabolism have been limited by the use of surrogate insulin sensitivity indices, small sample sizes, lack of blinding, and short follow-up duration.BACKGROUNDIn observational studies, coffee consumption has been consistently associated with a lower risk of type 2 diabetes mellitus. Trials examining the effect of coffee consumption on glucose metabolism have been limited by the use of surrogate insulin sensitivity indices, small sample sizes, lack of blinding, and short follow-up duration.We aimed to overcome limitations of previously conducted coffee trials in a randomized placebo-controlled trial of the effect of coffee consumption on insulin sensitivity.OBJECTIVESWe aimed to overcome limitations of previously conducted coffee trials in a randomized placebo-controlled trial of the effect of coffee consumption on insulin sensitivity.We conducted a 24-wk randomized placebo-controlled trial in 126 overweight, non-insulin sensitive (HOMA-IR ≥1.30), Chinese, Malay, and Asian-Indian males and females aged 35-69 y. Participants were randomly assigned to receive 4 cups of instant regular coffee (n = 62) or 4 cups of a coffee-like placebo beverage (n = 64) per day. The primary outcome was the amount of glucose metabolized per kilogram of body weight per minute (Mbw) assessed during steady-state conditions with a hyperinsulinemic euglycemic clamp. Secondary outcomes included other clamp-based insulin sensitivity measures, biological mediators of insulin sensitivity, and measures of fasting glucose metabolism.METHODSWe conducted a 24-wk randomized placebo-controlled trial in 126 overweight, non-insulin sensitive (HOMA-IR ≥1.30), Chinese, Malay, and Asian-Indian males and females aged 35-69 y. Participants were randomly assigned to receive 4 cups of instant regular coffee (n = 62) or 4 cups of a coffee-like placebo beverage (n = 64) per day. The primary outcome was the amount of glucose metabolized per kilogram of body weight per minute (Mbw) assessed during steady-state conditions with a hyperinsulinemic euglycemic clamp. Secondary outcomes included other clamp-based insulin sensitivity measures, biological mediators of insulin sensitivity, and measures of fasting glucose metabolism.Coffee consumption did not significantly change insulin sensitivity compared with placebo (percentage mean difference in Mbw = 4.0%; 95% CI: -8.3, 18.0%; P = 0.53). Furthermore, no significant differences in fasting plasma glucose (2.9%; 95% CI: -0.4, 6.3%; P = 0.09) or biological mediators of insulin resistance, such as plasma adiponectin (2.3%; 95% CI: -1.4, 6.2%; P = 0.22), were observed between coffee and placebo groups over 24 wk of intervention. Participants in the coffee arm experienced a loss of fat mass (FM) (-3.7%; 95% CI: -6.3, -1.1%; P = 0.006) and reduction in urinary creatinine concentrations (-21.2%; 95% CI: -31.4, -9.5%; P = 0.001) compared with participants in the placebo arm over 24 wk of intervention.RESULTSCoffee consumption did not significantly change insulin sensitivity compared with placebo (percentage mean difference in Mbw = 4.0%; 95% CI: -8.3, 18.0%; P = 0.53). Furthermore, no significant differences in fasting plasma glucose (2.9%; 95% CI: -0.4, 6.3%; P = 0.09) or biological mediators of insulin resistance, such as plasma adiponectin (2.3%; 95% CI: -1.4, 6.2%; P = 0.22), were observed between coffee and placebo groups over 24 wk of intervention. Participants in the coffee arm experienced a loss of fat mass (FM) (-3.7%; 95% CI: -6.3, -1.1%; P = 0.006) and reduction in urinary creatinine concentrations (-21.2%; 95% CI: -31.4, -9.5%; P = 0.001) compared with participants in the placebo arm over 24 wk of intervention.Consuming 4 cups/d of caffeinated coffee for 24 wk had no significant effect on insulin sensitivity or biological mediators of insulin resistance but was associated with a modest loss of FM and reduction in urinary creatinine concentrations.This trial was registered at clinicaltrials.gov as NCT01738399. Registered on November 28, 2012. Trial sponsor: Nestlé Research, Lausanne, Switzerland. Trial site: National University of Singapore.CONCLUSIONSConsuming 4 cups/d of caffeinated coffee for 24 wk had no significant effect on insulin sensitivity or biological mediators of insulin resistance but was associated with a modest loss of FM and reduction in urinary creatinine concentrations.This trial was registered at clinicaltrials.gov as NCT01738399. Registered on November 28, 2012. Trial sponsor: Nestlé Research, Lausanne, Switzerland. Trial site: National University of Singapore. ABSTRACT Background In observational studies, coffee consumption has been consistently associated with a lower risk of type 2 diabetes mellitus. Trials examining the effect of coffee consumption on glucose metabolism have been limited by the use of surrogate insulin sensitivity indices, small sample sizes, lack of blinding, and short follow-up duration. Objectives We aimed to overcome limitations of previously conducted coffee trials in a randomized placebo-controlled trial of the effect of coffee consumption on insulin sensitivity. Methods We conducted a 24-wk randomized placebo-controlled trial in 126 overweight, non–insulin sensitive (HOMA-IR ≥1.30), Chinese, Malay, and Asian-Indian males and females aged 35–69 y. Participants were randomly assigned to receive 4 cups of instant regular coffee (n = 62) or 4 cups of a coffee-like placebo beverage (n = 64) per day. The primary outcome was the amount of glucose metabolized per kilogram of body weight per minute (Mbw) assessed during steady-state conditions with a hyperinsulinemic euglycemic clamp. Secondary outcomes included other clamp-based insulin sensitivity measures, biological mediators of insulin sensitivity, and measures of fasting glucose metabolism. Results Coffee consumption did not significantly change insulin sensitivity compared with placebo (percentage mean difference in Mbw = 4.0%; 95% CI: −8.3, 18.0%; P = 0.53). Furthermore, no significant differences in fasting plasma glucose (2.9%; 95% CI: −0.4, 6.3%; P = 0.09) or biological mediators of insulin resistance, such as plasma adiponectin (2.3%; 95% CI: −1.4, 6.2%; P = 0.22), were observed between coffee and placebo groups over 24 wk of intervention. Participants in the coffee arm experienced a loss of fat mass (FM) (−3.7%; 95% CI: −6.3, −1.1%; P = 0.006) and reduction in urinary creatinine concentrations (−21.2%; 95% CI: −31.4, −9.5%; P = 0.001) compared with participants in the placebo arm over 24 wk of intervention. Conclusions Consuming 4 cups/d of caffeinated coffee for 24 wk had no significant effect on insulin sensitivity or biological mediators of insulin resistance but was associated with a modest loss of FM and reduction in urinary creatinine concentrations. This trial was registered at clinicaltrials.gov as NCT01738399. Registered on November 28, 2012. Trial sponsor: Nestlé Research, Lausanne, Switzerland. Trial site: National University of Singapore. In observational studies, coffee consumption has been consistently associated with a lower risk of type 2 diabetes mellitus. Trials examining the effect of coffee consumption on glucose metabolism have been limited by the use of surrogate insulin sensitivity indices, small sample sizes, lack of blinding, and short follow-up duration. We aimed to overcome limitations of previously conducted coffee trials in a randomized placebo-controlled trial of the effect of coffee consumption on insulin sensitivity. We conducted a 24-wk randomized placebo-controlled trial in 126 overweight, non-insulin sensitive (HOMA-IR ≥1.30), Chinese, Malay, and Asian-Indian males and females aged 35-69 y. Participants were randomly assigned to receive 4 cups of instant regular coffee (n = 62) or 4 cups of a coffee-like placebo beverage (n = 64) per day. The primary outcome was the amount of glucose metabolized per kilogram of body weight per minute (Mbw) assessed during steady-state conditions with a hyperinsulinemic euglycemic clamp. Secondary outcomes included other clamp-based insulin sensitivity measures, biological mediators of insulin sensitivity, and measures of fasting glucose metabolism. Coffee consumption did not significantly change insulin sensitivity compared with placebo (percentage mean difference in Mbw = 4.0%; 95% CI: -8.3, 18.0%; P = 0.53). Furthermore, no significant differences in fasting plasma glucose (2.9%; 95% CI: -0.4, 6.3%; P = 0.09) or biological mediators of insulin resistance, such as plasma adiponectin (2.3%; 95% CI: -1.4, 6.2%; P = 0.22), were observed between coffee and placebo groups over 24 wk of intervention. Participants in the coffee arm experienced a loss of fat mass (FM) (-3.7%; 95% CI: -6.3, -1.1%; P = 0.006) and reduction in urinary creatinine concentrations (-21.2%; 95% CI: -31.4, -9.5%; P = 0.001) compared with participants in the placebo arm over 24 wk of intervention. Consuming 4 cups/d of caffeinated coffee for 24 wk had no significant effect on insulin sensitivity or biological mediators of insulin resistance but was associated with a modest loss of FM and reduction in urinary creatinine concentrations.This trial was registered at clinicaltrials.gov as NCT01738399. Registered on November 28, 2012. Trial sponsor: Nestlé Research, Lausanne, Switzerland. Trial site: National University of Singapore. In observational studies, coffee consumption has been consistently associated with a lower risk of type 2 diabetes mellitus. Trials examining the effect of coffee consumption on glucose metabolism have been limited by the use of surrogate insulin sensitivity indices, small sample sizes, lack of blinding, and short follow-up duration. We aimed to overcome limitations of previously conducted coffee trials in a randomized placebo-controlled trial of the effect of coffee consumption on insulin sensitivity. We conducted a 24-wk randomized placebo-controlled trial in 126 overweight, non–insulin sensitive (HOMA-IR ≥1.30), Chinese, Malay, and Asian-Indian males and females aged 35–69 y. Participants were randomly assigned to receive 4 cups of instant regular coffee (n = 62) or 4 cups of a coffee-like placebo beverage (n = 64) per day. The primary outcome was the amount of glucose metabolized per kilogram of body weight per minute (Mbw) assessed during steady-state conditions with a hyperinsulinemic euglycemic clamp. Secondary outcomes included other clamp-based insulin sensitivity measures, biological mediators of insulin sensitivity, and measures of fasting glucose metabolism. Coffee consumption did not significantly change insulin sensitivity compared with placebo (percentage mean difference in Mbw = 4.0%; 95% CI: −8.3, 18.0%; P = 0.53). Furthermore, no significant differences in fasting plasma glucose (2.9%; 95% CI: −0.4, 6.3%; P = 0.09) or biological mediators of insulin resistance, such as plasma adiponectin (2.3%; 95% CI: −1.4, 6.2%; P = 0.22), were observed between coffee and placebo groups over 24 wk of intervention. Participants in the coffee arm experienced a loss of fat mass (FM) (−3.7%; 95% CI: −6.3, −1.1%; P = 0.006) and reduction in urinary creatinine concentrations (−21.2%; 95% CI: −31.4, −9.5%; P = 0.001) compared with participants in the placebo arm over 24 wk of intervention. Consuming 4 cups/d of caffeinated coffee for 24 wk had no significant effect on insulin sensitivity or biological mediators of insulin resistance but was associated with a modest loss of FM and reduction in urinary creatinine concentrations. This trial was registered at clinicaltrials.gov as NCT01738399. Registered on November 28, 2012. Trial sponsor: Nestlé Research, Lausanne, Switzerland. Trial site: National University of Singapore. Background In observational studies, coffee consumption has been consistently associated with a lower risk of type 2 diabetes mellitus. Trials examining the effect of coffee consumption on glucose metabolism have been limited by the use of surrogate insulin sensitivity indices, small sample sizes, lack of blinding, and short follow-up duration. Objectives We aimed to overcome limitations of previously conducted coffee trials in a randomized placebo-controlled trial of the effect of coffee consumption on insulin sensitivity. Methods We conducted a 24-wk randomized placebo-controlled trial in 126 overweight, non–insulin sensitive (HOMA-IR ≥1.30), Chinese, Malay, and Asian-Indian males and females aged 35–69 y. Participants were randomly assigned to receive 4 cups of instant regular coffee (n = 62) or 4 cups of a coffee-like placebo beverage (n = 64) per day. The primary outcome was the amount of glucose metabolized per kilogram of body weight per minute (Mbw) assessed during steady-state conditions with a hyperinsulinemic euglycemic clamp. Secondary outcomes included other clamp-based insulin sensitivity measures, biological mediators of insulin sensitivity, and measures of fasting glucose metabolism. Results Coffee consumption did not significantly change insulin sensitivity compared with placebo (percentage mean difference in Mbw = 4.0%; 95% CI: −8.3, 18.0%; P = 0.53). Furthermore, no significant differences in fasting plasma glucose (2.9%; 95% CI: −0.4, 6.3%; P = 0.09) or biological mediators of insulin resistance, such as plasma adiponectin (2.3%; 95% CI: −1.4, 6.2%; P = 0.22), were observed between coffee and placebo groups over 24 wk of intervention. Participants in the coffee arm experienced a loss of fat mass (FM) (−3.7%; 95% CI: −6.3, −1.1%; P = 0.006) and reduction in urinary creatinine concentrations (−21.2%; 95% CI: −31.4, −9.5%; P = 0.001) compared with participants in the placebo arm over 24 wk of intervention. Conclusions Consuming 4 cups/d of caffeinated coffee for 24 wk had no significant effect on insulin sensitivity or biological mediators of insulin resistance but was associated with a modest loss of FM and reduction in urinary creatinine concentrations. This trial was registered at clinicaltrials.gov as NCT01738399. Registered on November 28, 2012. Trial sponsor: Nestlé Research, Lausanne, Switzerland. Trial site: National University of Singapore. |
| Author | Tay, Zoey Rebello, Salome Antonette Seah, Sharna Si-Ying Tai, E-Shyong Darimont, Christian van Dam, Rob M Alperet, Derrick Johnston Khoo, Eric Yin-Hao Chou, Chieh Jason Tai, Bee-Choo Emady-Azar, Shahram |
| Author_xml | – sequence: 1 givenname: Derrick Johnston surname: Alperet fullname: Alperet, Derrick Johnston email: dalperet@hsph.harvard.edu organization: NUS Graduate School for Integrative Sciences and Engineering, National University of Singapore (NUS), Singapore – sequence: 2 givenname: Salome Antonette surname: Rebello fullname: Rebello, Salome Antonette organization: Saw Swee Hock School of Public Health, National University of Singapore, Singapore – sequence: 3 givenname: Eric Yin-Hao surname: Khoo fullname: Khoo, Eric Yin-Hao organization: Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore – sequence: 4 givenname: Zoey surname: Tay fullname: Tay, Zoey organization: Saw Swee Hock School of Public Health, National University of Singapore, Singapore – sequence: 5 givenname: Sharna Si-Ying surname: Seah fullname: Seah, Sharna Si-Ying organization: Saw Swee Hock School of Public Health, National University of Singapore, Singapore – sequence: 6 givenname: Bee-Choo surname: Tai fullname: Tai, Bee-Choo organization: Saw Swee Hock School of Public Health, National University of Singapore, Singapore – sequence: 7 givenname: E-Shyong surname: Tai fullname: Tai, E-Shyong organization: Saw Swee Hock School of Public Health, National University of Singapore, Singapore – sequence: 8 givenname: Shahram surname: Emady-Azar fullname: Emady-Azar, Shahram organization: Clinical Development Unit, Nestlé Research, Lausanne, Switzerland – sequence: 9 givenname: Chieh Jason surname: Chou fullname: Chou, Chieh Jason organization: Nestlé Institute of Health Sciences, Nestlé Research, Lausanne, Switzerland – sequence: 10 givenname: Christian surname: Darimont fullname: Darimont, Christian organization: Nestlé Institute of Health Sciences, Nestlé Research, Lausanne, Switzerland – sequence: 11 givenname: Rob M surname: van Dam fullname: van Dam, Rob M email: rob.van.dam@nus.edu.sg organization: NUS Graduate School for Integrative Sciences and Engineering, National University of Singapore (NUS), Singapore |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/31891374$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1093/ajcn/33.5.989 10.1038/srep36500 10.1016/S0140-6736(13)62154-6 10.2337/diacare.25.2.364 10.1093/ajcn/81.1.74 10.1016/j.foodres.2012.02.023 10.1042/cs0600527 10.2337/diacare.29.02.06.dc05-1512 10.4239/wjd.v1.i2.36 10.3945/ajcn.113.069526 10.1016/j.cct.2003.10.016 10.1093/ajcn.83.3.674 10.1002/hep.23116 10.1016/S0140-6736(14)60613-9 10.1016/S0140-6736(02)11436-X 10.1186/1471-2288-11-141 10.2337/dc13-1203 10.1016/j.jsams.2014.07.017 10.1016/j.foodres.2014.05.032 10.1155/2012/207426 10.1016/j.conctc.2016.06.013 10.1016/j.foodres.2012.06.032 10.2337/diacare.27.12.2990 10.1016/0091-3057(94)90196-1 10.1021/jf00056a039 10.1136/bmj.c869 10.3945/ajcn.115.112755 10.2337/diacare.27.6.1487 10.1172/JCI109718 10.1093/ajcn/51.5.759 10.1089/jcr.2010.0007 10.1093/ajcn/88.4.979 10.1038/ijo.2017.310 10.1007/s00394-014-0763-3 10.2337/diabetes.50.10.2349 10.1007/s11886-013-0403-1 10.1186/1475-2891-10-93 10.1249/01.MSS.0000078924.61453.FB 10.1186/1475-2891-10-48 10.3945/ajcn.2009.28548 |
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| Keywords | PP T2DM Mbw Mffm FM M-value COMETH DXA FFM M/Ibw M/I ratio insulin sensitivity metabolic health type 2 diabetes adult-onset diabetes mellitus Adipo-IR coffee M/Iffm BIA CGA insulin resistance humans bpm hyperinsulinemic euglycemic clamp |
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| References | Urgert, van der Weg, Kosmeijer-Schuil, van de Bovenkamp, Hovenier, Katan (bib44) 1995; 43 Lecoultre, Carrel, Egli, Binnert, Boss, MacMillan, Kreis, Boesch, Darimont, Tappy (bib8) 2014; 99 Brehm, Roden (bib51) 2007 Yoshida, Sakane, Umekawa, Kondo (bib39) 1994; 18 Ding, Bhupathiraju, Chen, van Dam, Hu (bib4) 2014; 37 Naidoo, Chen, Rebello, Speer, Tai, Lee, Buchmann, Koelling-Speer, van Dam (bib45) 2011; 10 McFarlane, Pardomuan (bib47) 2013 Deibert, DeFronzo (bib26) 1980; 65 Herber-Gast, van Essen, Verschuren, Stehouwer, Gansevoort, Bakker, Spijkerman (bib29) 2016; 103 Wedick, Brennan, Sun, Hu, Mantzoros, van Dam (bib11) 2011; 10 Davoodi, Hajimiresmaiel, Ajami, Mohseni-Bandpei, Ayatollahi, Dowlatshahi, Javedan, Pazoki-Toroudi (bib33) 2014; 13 Racotta, Leblanc, Richard (bib40) 1994; 48 Ludwig, Sanchez, Caemmerer, Kroh, De Peña, Cid (bib42) 2012; 48 Wallace, Levy, Matthews (bib16) 2004; 27 van Dam, Willett, Manson, Hu (bib50) 2006; 29 Saunders, Blevins, Broeder (bib53) 1998; 30 Health Promotion Board. Energy & nutrient composition of food. [Internet]. [cited December 4, 2016]. Available from . (bib1) 2015 Larsen, Mikkelsen, Frederiksen, Heitmann (bib30) 2018; 42 Sun, French, Martin, Younghusband, Green, Xie, Mathews, Barron, Fitzpatrick, Gulliver (bib52) 2005; 81 van Dam, Feskens (bib5) 2002; 360 Craig, Marshall, Sjostrom, Bauman, Booth, Ainsworth, Pratt, Ekelund, Yngve, Sallis (bib20) 2003; 35 Kempf, Herder, Erlund, Kolb, Martin, Carstensen, Koenig, Sundvall, Bidel, Kuha (bib9) 2010; 91 Rebello, van Dam (bib41) 2013; 15 Thompson, Thompson, Prestridge, Bailey, Bean, Brown, McDaniel (bib54) 1991; 31 Kwok, Leung, Schooling (bib27) 2016; 6 Jung, Shetty, James, Barrand, Callingham (bib38) 1981; 60 Ley, Hamdy, Mohan, Hu (bib3) 2014; 383 Singh, Saxena (bib14) 2010; 1 Newby, Sykes, DiGirolamo (bib34) 1988; 255 Zhang, Linforth, Fisk (bib43) 2012; 49 Astrup, Toubro, Cannon, Hein, Breum, Madsen (bib37) 1990; 51 Alperet, Rebello, Khoo, Tay, Seah, Tai, Emady-Azar, Chou, Darimont, van Dam (bib13) 2016; 4 Lopez-Garcia, van Dam, Rajpathak, Willett, Manson, Hu (bib31) 2006; 83 Neo (bib48) 2019 Lane (bib6) 2011; 1 Bang, Ni, Davis (bib23) 2004; 25 Greer, Hudson, Ross, Graham (bib24) 2001; 50 Nang, Gitau Ngunjiri, Wu, Salim, Tai, Lee, Van Dam (bib19) 2011; 11 Bakuradze, Parra, Riedel, Somoza, Lang, Dieminger, Hofmann, Winkler, Hassmann, Marko (bib32) 2014; 63 Kempf, Kolb, Gartner, Bytof, Stiebitz, Lantz, Lang, Hofmann, Martin (bib10) 2015; 54 Brown (bib18) 1998 Gastaldelli, Harrison, Belfort-Aguilar, Hardies, Balas, Schenker, Cusi (bib17) 2009; 50 Ohnaka, Ikeda, Maki, Okada, Shimazoe, Adachi, Nomura, Takayanagi, Kono (bib12) 2012; 2012 Moher, Hopewell, Schulz, Montori, Gotzsche, Devereaux, Elbourne, Egger, Altman (bib22) 2010; 340 Acheson, Zahorska-Markiewicz, Pittet, Anantharaman, Jequier (bib36) 1980; 33 Kahn, Cooper, Del Prato (bib2) 2014; 383 Zhang, Coca, Casa, Antonio, Green, Bishop (bib28) 2015; 18 van Dam, Pasman, Verhoef (bib7) 2004; 27 DeFronzo, Tobin, Andres (bib15) 1979; 237 Keijzers, De Galan, Tack, Smits (bib25) 2002; 25 Kusaka, Ui (bib35) 1977; 232 Odegaard, Pereira, Koh, Arakawa, Lee, Yu (bib49) 2008; 88 Coffee Premiumisation in Southeast Asia. Euromonitor International, 2018. Keijzers (10.1093/ajcn/nqz306_bib25) 2002; 25 Deibert (10.1093/ajcn/nqz306_bib26) 1980; 65 Kempf (10.1093/ajcn/nqz306_bib9) 2010; 91 Zhang (10.1093/ajcn/nqz306_bib28) 2015; 18 Jung (10.1093/ajcn/nqz306_bib38) 1981; 60 Lopez-Garcia (10.1093/ajcn/nqz306_bib31) 2006; 83 Zhang (10.1093/ajcn/nqz306_bib43) 2012; 49 Lane (10.1093/ajcn/nqz306_bib6) 2011; 1 McFarlane (10.1093/ajcn/nqz306_bib47) 2013 van Dam (10.1093/ajcn/nqz306_bib7) 2004; 27 van Dam (10.1093/ajcn/nqz306_bib5) 2002; 360 Ludwig (10.1093/ajcn/nqz306_bib42) 2012; 48 Singh (10.1093/ajcn/nqz306_bib14) 2010; 1 Ley (10.1093/ajcn/nqz306_bib3) 2014; 383 Yoshida (10.1093/ajcn/nqz306_bib39) 1994; 18 Acheson (10.1093/ajcn/nqz306_bib36) 1980; 33 10.1093/ajcn/nqz306_bib21 van Dam (10.1093/ajcn/nqz306_bib50) 2006; 29 Craig (10.1093/ajcn/nqz306_bib20) 2003; 35 Larsen (10.1093/ajcn/nqz306_bib30) 2018; 42 Bakuradze (10.1093/ajcn/nqz306_bib32) 2014; 63 Thompson (10.1093/ajcn/nqz306_bib54) 1991; 31 Naidoo (10.1093/ajcn/nqz306_bib45) 2011; 10 Gastaldelli (10.1093/ajcn/nqz306_bib17) 2009; 50 Alperet (10.1093/ajcn/nqz306_bib13) 2016; 4 Kwok (10.1093/ajcn/nqz306_bib27) 2016; 6 Kusaka (10.1093/ajcn/nqz306_bib35) 1977; 232 Bang (10.1093/ajcn/nqz306_bib23) 2004; 25 Ding (10.1093/ajcn/nqz306_bib4) 2014; 37 Davoodi (10.1093/ajcn/nqz306_bib33) 2014; 13 Rebello (10.1093/ajcn/nqz306_bib41) 2013; 15 Wedick (10.1093/ajcn/nqz306_bib11) 2011; 10 Nang (10.1093/ajcn/nqz306_bib19) 2011; 11 Brehm (10.1093/ajcn/nqz306_bib51) 2007 Saunders (10.1093/ajcn/nqz306_bib53) 1998; 30 Herber-Gast (10.1093/ajcn/nqz306_bib29) 2016; 103 Odegaard (10.1093/ajcn/nqz306_bib49) 2008; 88 DeFronzo (10.1093/ajcn/nqz306_bib15) 1979; 237 Moher (10.1093/ajcn/nqz306_bib22) 2010; 340 Greer (10.1093/ajcn/nqz306_bib24) 2001; 50 Lecoultre (10.1093/ajcn/nqz306_bib8) 2014; 99 Racotta (10.1093/ajcn/nqz306_bib40) 1994; 48 Kempf (10.1093/ajcn/nqz306_bib10) 2015; 54 Brown (10.1093/ajcn/nqz306_bib18) 1998 Kahn (10.1093/ajcn/nqz306_bib2) 2014; 383 Sun (10.1093/ajcn/nqz306_bib52) 2005; 81 Ohnaka (10.1093/ajcn/nqz306_bib12) 2012; 2012 Wallace (10.1093/ajcn/nqz306_bib16) 2004; 27 Astrup (10.1093/ajcn/nqz306_bib37) 1990; 51 (10.1093/ajcn/nqz306_bib1) 2015 10.1093/ajcn/nqz306_bib46 Urgert (10.1093/ajcn/nqz306_bib44) 1995; 43 Newby (10.1093/ajcn/nqz306_bib34) 1988; 255 Neo (10.1093/ajcn/nqz306_bib48) 2019 31919498 - Am J Clin Nutr. 2020 Feb 1;111(2):248-249 |
| References_xml | – volume: 4 start-page: 105 year: 2016 end-page: 117 ident: bib13 article-title: A randomized placebo-controlled trial of the effect of coffee consumption on insulin sensitivity: design and baseline characteristics of the Coffee for METabolic Health (COMETH) study publication-title: Contemp Clin Trials Commun. – volume: 50 start-page: 2349 year: 2001 end-page: 2354 ident: bib24 article-title: Caffeine ingestion decreases glucose disposal during a hyperinsulinemic-euglycemic clamp in sedentary humans publication-title: Diabetes. – volume: 255 start-page: E716 year: 1988 end-page: E762 ident: bib34 article-title: Regional differences in adipocyte lactate production from glucose publication-title: Am J Physiol. – volume: 83 start-page: 674 year: 2006 end-page: 680 ident: bib31 article-title: Changes in caffeine intake and long-term weight change in men and women publication-title: Am J Clin Nutr. – volume: 10 start-page: 93 year: 2011 ident: bib11 article-title: Effects of caffeinated and decaffeinated coffee on biological risk factors for type 2 diabetes: a randomized controlled trial publication-title: Nutr J. – start-page: 43 year: 2007 end-page: 76 ident: bib51 article-title: Glucose clamp techniques publication-title: Clinical diabetes research: methods and techniques. – volume: 81 start-page: 74 year: 2005 end-page: 78 ident: bib52 article-title: Comparison of multifrequency bioelectrical impedance analysis with dual-energy X-ray absorptiometry for assessment of percentage body fat in a large, healthy population publication-title: Am J Clin Nutr. – volume: 33 start-page: 989 year: 1980 end-page: 997 ident: bib36 article-title: Caffeine and coffee: their influence on metabolic rate and substrate utilization in normal weight and obese individuals publication-title: Am J Clin Nutr. – volume: 27 start-page: 2990 year: 2004 end-page: 2992 ident: bib7 article-title: Effects of coffee consumption on fasting blood glucose and insulin concentrations: randomized controlled trials in healthy volunteers publication-title: Diabetes Care. – year: 2019 ident: bib48 article-title: Explainer: why your cafe latte costs S$6 publication-title: Today. – volume: 99 start-page: 268 year: 2014 end-page: 275 ident: bib8 article-title: Coffee consumption attenuates short-term fructose-induced liver insulin resistance in healthy men publication-title: Am J Clin Nutr. – volume: 42 start-page: 880 year: 2018 end-page: 886 ident: bib30 article-title: Habitual coffee consumption and changes in measures of adiposity: a comprehensive study of longitudinal associations publication-title: Int J Obes (Lond). – volume: 340 start-page: c869 year: 2010 ident: bib22 article-title: CONSORT 2010 explanation and elaboration: updated guidelines for reporting parallel group randomised trials publication-title: Br Med J. – volume: 49 start-page: 27 year: 2012 end-page: 31 ident: bib43 article-title: Cafestol extraction yield from different coffee brew mechanisms publication-title: Food Res Int. – volume: 27 start-page: 1487 year: 2004 end-page: 1495 ident: bib16 article-title: Use and abuse of HOMA modeling publication-title: Diabetes Care. – volume: 54 start-page: 845 year: 2015 end-page: 854 ident: bib10 article-title: Cardiometabolic effects of two coffee blends differing in content for major constituents in overweight adults: a randomized controlled trial publication-title: Eur J Nutr. – volume: 25 start-page: 364 year: 2002 end-page: 369 ident: bib25 article-title: Caffeine can decrease insulin sensitivity in humans publication-title: Diabetes Care. – volume: 88 start-page: 979 year: 2008 end-page: 985 ident: bib49 article-title: Coffee, tea, and incident type 2 diabetes: the Singapore Chinese Health Study publication-title: Am J Clin Nutr. – start-page: 155 year: 1998 end-page: 157 ident: bib18 article-title: Coefficient of variation publication-title: Applied multivariate statistics in geohydrology and related sciences. – volume: 103 start-page: 1370 year: 2016 end-page: 1377 ident: bib29 article-title: Coffee and tea consumption in relation to estimated glomerular filtration rate: results from the population-based longitudinal Doetinchem Cohort Study publication-title: Am J Clin Nutr. – volume: 13 start-page: 707 year: 2014 end-page: 718 ident: bib33 article-title: Caffeine treatment prevented from weight regain after calorie shifting diet induced weight loss publication-title: Iran J Pharm Res. – volume: 37 start-page: 569 year: 2014 end-page: 586 ident: bib4 article-title: Caffeinated and decaffeinated coffee consumption and risk of type 2 diabetes: a systematic review and a dose-response meta-analysis publication-title: Diabetes Care. – reference: Health Promotion Board. Energy & nutrient composition of food. [Internet]. [cited December 4, 2016]. Available from: – year: 2015 ident: bib1 publication-title: Diabetes atlas. – volume: 51 start-page: 759 year: 1990 end-page: 767 ident: bib37 article-title: Caffeine: a double-blind, placebo-controlled study of its thermogenic, metabolic, and cardiovascular effects in healthy volunteers publication-title: Am J Clin Nutr. – volume: 43 start-page: 2167 year: 1995 end-page: 2172 ident: bib44 article-title: Levels of the cholesterol-elevating diterpenes cafestol and kahweol in various coffee brews publication-title: J Agric Food Chem. – volume: 48 start-page: 887 year: 1994 end-page: 892 ident: bib40 article-title: The effect of caffeine on food intake in rats: involvement of corticotropin-releasing factor and the sympatho-adrenal system publication-title: Pharmacol Biochem Behav. – volume: 1 start-page: 36 year: 2010 end-page: 47 ident: bib14 article-title: Surrogate markers of insulin resistance: a review publication-title: World J Diabetes. – year: 2013 ident: bib47 article-title: Asia’s taste for robusta coffee transforms market publication-title: Chicago Tribune. – volume: 65 start-page: 717 year: 1980 end-page: 721 ident: bib26 article-title: Epinephrine-induced insulin resistance in man publication-title: J Clin Invest. – reference: Coffee Premiumisation in Southeast Asia. Euromonitor International, 2018. – volume: 232 start-page: E145 year: 1977 end-page: E155 ident: bib35 article-title: Activation of the Cori cycle by epinephrine publication-title: Am J Physiol. – volume: 48 start-page: 57 year: 2012 end-page: 64 ident: bib42 article-title: Extraction of coffee antioxidants: impact of brewing time and method publication-title: Food Res Int. – volume: 10 start-page: 48 year: 2011 ident: bib45 article-title: Cholesterol-raising diterpenes in types of coffee commonly consumed in Singapore, Indonesia and India and associations with blood lipids: a survey and cross sectional study publication-title: Nutr J. – volume: 383 start-page: 1068 year: 2014 end-page: 1083 ident: bib2 article-title: Pathophysiology and treatment of type 2 diabetes: perspectives on the past, present, and future publication-title: Lancet. – volume: 60 start-page: 527 year: 1981 end-page: 535 ident: bib38 article-title: Caffeine: its effect on catecholamines and metabolism in lean and obese humans publication-title: Clin Sci. – volume: 91 start-page: 950 year: 2010 end-page: 957 ident: bib9 article-title: Effects of coffee consumption on subclinical inflammation and other risk factors for type 2 diabetes: a clinical trial publication-title: Am J Clin Nutr. – volume: 383 start-page: 1999 year: 2014 end-page: 2007 ident: bib3 article-title: Prevention and management of type 2 diabetes: dietary components and nutritional strategies publication-title: Lancet. – volume: 360 start-page: 1477 year: 2002 end-page: 1478 ident: bib5 article-title: Coffee consumption and risk of type 2 diabetes mellitus publication-title: Lancet. – volume: 237 start-page: E214 year: 1979 end-page: E242 ident: bib15 article-title: Glucose clamp technique: a method for quantifying insulin secretion and resistance publication-title: Am J Physiol. – volume: 63 start-page: 420 year: 2014 end-page: 427 ident: bib32 article-title: Four-week coffee consumption affects energy intake, satiety regulation, body fat, and protects DNA integrity publication-title: Food Res Int. – volume: 1 start-page: 23 year: 2011 end-page: 28 ident: bib6 article-title: Caffeine, glucose metabolism, and type 2 diabetes publication-title: J Caffeine Res. – volume: 11 start-page: 141 year: 2011 ident: bib19 article-title: Validity of the International Physical Activity Questionnaire and the Singapore Prospective Study Program physical activity questionnaire in a multiethnic urban Asian population publication-title: BMC Med Res Method. – volume: 18 start-page: 569 year: 2015 end-page: 574 ident: bib28 article-title: Caffeine and diuresis during rest and exercise: a meta-analysis publication-title: J Sci Med Sport. – volume: 35 start-page: 1381 year: 2003 end-page: 1395 ident: bib20 article-title: International physical activity questionnaire: 12-country reliability and validity publication-title: Med Sci Sports Exerc. – reference: . – volume: 31 start-page: 565 year: 1991 end-page: 570 ident: bib54 article-title: Effects of hydration and dehydration on body composition analysis: a comparative study of bioelectric impedance analysis and hydrodensitometry publication-title: J Sports Med Phys Fitness. – volume: 2012 start-page: 207426 year: 2012 ident: bib12 article-title: Effects of 16-week consumption of caffeinated and decaffeinated instant coffee on glucose metabolism in a randomized controlled trial publication-title: J Nutr Metab. – volume: 50 start-page: 1087 year: 2009 end-page: 1093 ident: bib17 article-title: Importance of changes in adipose tissue insulin resistance to histological response during thiazolidinedione treatment of patients with nonalcoholic steatohepatitis publication-title: Hepatology. – volume: 30 start-page: 885 year: 1998 end-page: 892 ident: bib53 article-title: Effects of hydration changes on bioelectrical impedance in endurance trained individuals publication-title: Med Sci Sports Exerc. – volume: 25 start-page: 143 year: 2004 end-page: 156 ident: bib23 article-title: Assessment of blinding in clinical trials publication-title: Control Clin Trials. – volume: 18 start-page: 345 year: 1994 end-page: 350 ident: bib39 article-title: Relationship between basal metabolic rate, thermogenic response to caffeine, and body weight loss following combined low calorie and exercise treatment in obese women publication-title: Int J Obes Relat Metab Disord. – volume: 15 start-page: 403 year: 2013 ident: bib41 article-title: Coffee consumption and cardiovascular health: getting to the heart of the matter publication-title: Curr Cardiol Rep. – volume: 6 start-page: 36500 year: 2016 ident: bib27 article-title: Habitual coffee consumption and risk of type 2 diabetes, ischemic heart disease, depression and Alzheimer’s disease: a Mendelian randomization study publication-title: Sci Rep. – volume: 29 start-page: 398 year: 2006 end-page: 403 ident: bib50 article-title: Coffee, caffeine, and risk of type 2 diabetes: a prospective cohort study in younger and middle-aged U.S. women publication-title: Diabetes Care. – volume: 33 start-page: 989 issue: 5 year: 1980 ident: 10.1093/ajcn/nqz306_bib36 article-title: Caffeine and coffee: their influence on metabolic rate and substrate utilization in normal weight and obese individuals publication-title: Am J Clin Nutr. doi: 10.1093/ajcn/33.5.989 – volume: 6 start-page: 36500 year: 2016 ident: 10.1093/ajcn/nqz306_bib27 article-title: Habitual coffee consumption and risk of type 2 diabetes, ischemic heart disease, depression and Alzheimer’s disease: a Mendelian randomization study publication-title: Sci Rep. doi: 10.1038/srep36500 – volume: 255 start-page: E716 issue: 5 Pt 1 year: 1988 ident: 10.1093/ajcn/nqz306_bib34 article-title: Regional differences in adipocyte lactate production from glucose publication-title: Am J Physiol. – year: 2019 ident: 10.1093/ajcn/nqz306_bib48 article-title: Explainer: why your cafe latte costs S$6 publication-title: Today. – volume: 383 start-page: 1068 issue: 9922 year: 2014 ident: 10.1093/ajcn/nqz306_bib2 article-title: Pathophysiology and treatment of type 2 diabetes: perspectives on the past, present, and future publication-title: Lancet. doi: 10.1016/S0140-6736(13)62154-6 – volume: 25 start-page: 364 issue: 2 year: 2002 ident: 10.1093/ajcn/nqz306_bib25 article-title: Caffeine can decrease insulin sensitivity in humans publication-title: Diabetes Care. doi: 10.2337/diacare.25.2.364 – volume: 237 start-page: E214 issue: 3 year: 1979 ident: 10.1093/ajcn/nqz306_bib15 article-title: Glucose clamp technique: a method for quantifying insulin secretion and resistance publication-title: Am J Physiol. – volume: 81 start-page: 74 issue: 1 year: 2005 ident: 10.1093/ajcn/nqz306_bib52 article-title: Comparison of multifrequency bioelectrical impedance analysis with dual-energy X-ray absorptiometry for assessment of percentage body fat in a large, healthy population publication-title: Am J Clin Nutr. doi: 10.1093/ajcn/81.1.74 – volume: 30 start-page: 885 issue: 6 year: 1998 ident: 10.1093/ajcn/nqz306_bib53 article-title: Effects of hydration changes on bioelectrical impedance in endurance trained individuals publication-title: Med Sci Sports Exerc. – volume: 48 start-page: 57 issue: 1 year: 2012 ident: 10.1093/ajcn/nqz306_bib42 article-title: Extraction of coffee antioxidants: impact of brewing time and method publication-title: Food Res Int. doi: 10.1016/j.foodres.2012.02.023 – volume: 13 start-page: 707 issue: 2 year: 2014 ident: 10.1093/ajcn/nqz306_bib33 article-title: Caffeine treatment prevented from weight regain after calorie shifting diet induced weight loss publication-title: Iran J Pharm Res. – volume: 60 start-page: 527 issue: 5 year: 1981 ident: 10.1093/ajcn/nqz306_bib38 article-title: Caffeine: its effect on catecholamines and metabolism in lean and obese humans publication-title: Clin Sci. doi: 10.1042/cs0600527 – ident: 10.1093/ajcn/nqz306_bib21 – volume: 29 start-page: 398 issue: 2 year: 2006 ident: 10.1093/ajcn/nqz306_bib50 article-title: Coffee, caffeine, and risk of type 2 diabetes: a prospective cohort study in younger and middle-aged U.S. women publication-title: Diabetes Care. doi: 10.2337/diacare.29.02.06.dc05-1512 – volume: 1 start-page: 36 issue: 2 year: 2010 ident: 10.1093/ajcn/nqz306_bib14 article-title: Surrogate markers of insulin resistance: a review publication-title: World J Diabetes. doi: 10.4239/wjd.v1.i2.36 – volume: 99 start-page: 268 issue: 2 year: 2014 ident: 10.1093/ajcn/nqz306_bib8 article-title: Coffee consumption attenuates short-term fructose-induced liver insulin resistance in healthy men publication-title: Am J Clin Nutr. doi: 10.3945/ajcn.113.069526 – volume: 25 start-page: 143 issue: 2 year: 2004 ident: 10.1093/ajcn/nqz306_bib23 article-title: Assessment of blinding in clinical trials publication-title: Control Clin Trials. doi: 10.1016/j.cct.2003.10.016 – volume: 83 start-page: 674 issue: 3 year: 2006 ident: 10.1093/ajcn/nqz306_bib31 article-title: Changes in caffeine intake and long-term weight change in men and women publication-title: Am J Clin Nutr. doi: 10.1093/ajcn.83.3.674 – volume: 50 start-page: 1087 issue: 4 year: 2009 ident: 10.1093/ajcn/nqz306_bib17 article-title: Importance of changes in adipose tissue insulin resistance to histological response during thiazolidinedione treatment of patients with nonalcoholic steatohepatitis publication-title: Hepatology. doi: 10.1002/hep.23116 – volume: 232 start-page: E145 issue: 2 year: 1977 ident: 10.1093/ajcn/nqz306_bib35 article-title: Activation of the Cori cycle by epinephrine publication-title: Am J Physiol. – volume: 383 start-page: 1999 issue: 9933 year: 2014 ident: 10.1093/ajcn/nqz306_bib3 article-title: Prevention and management of type 2 diabetes: dietary components and nutritional strategies publication-title: Lancet. doi: 10.1016/S0140-6736(14)60613-9 – volume: 360 start-page: 1477 issue: 9344 year: 2002 ident: 10.1093/ajcn/nqz306_bib5 article-title: Coffee consumption and risk of type 2 diabetes mellitus publication-title: Lancet. doi: 10.1016/S0140-6736(02)11436-X – volume: 11 start-page: 141 year: 2011 ident: 10.1093/ajcn/nqz306_bib19 article-title: Validity of the International Physical Activity Questionnaire and the Singapore Prospective Study Program physical activity questionnaire in a multiethnic urban Asian population publication-title: BMC Med Res Method. doi: 10.1186/1471-2288-11-141 – volume: 37 start-page: 569 issue: 2 year: 2014 ident: 10.1093/ajcn/nqz306_bib4 article-title: Caffeinated and decaffeinated coffee consumption and risk of type 2 diabetes: a systematic review and a dose-response meta-analysis publication-title: Diabetes Care. doi: 10.2337/dc13-1203 – volume: 18 start-page: 569 issue: 5 year: 2015 ident: 10.1093/ajcn/nqz306_bib28 article-title: Caffeine and diuresis during rest and exercise: a meta-analysis publication-title: J Sci Med Sport. doi: 10.1016/j.jsams.2014.07.017 – volume: 63 start-page: 420 issue: Pt C year: 2014 ident: 10.1093/ajcn/nqz306_bib32 article-title: Four-week coffee consumption affects energy intake, satiety regulation, body fat, and protects DNA integrity publication-title: Food Res Int. doi: 10.1016/j.foodres.2014.05.032 – volume: 2012 start-page: 207426 year: 2012 ident: 10.1093/ajcn/nqz306_bib12 article-title: Effects of 16-week consumption of caffeinated and decaffeinated instant coffee on glucose metabolism in a randomized controlled trial publication-title: J Nutr Metab. doi: 10.1155/2012/207426 – year: 2013 ident: 10.1093/ajcn/nqz306_bib47 article-title: Asia’s taste for robusta coffee transforms market publication-title: Chicago Tribune. – volume: 4 start-page: 105 year: 2016 ident: 10.1093/ajcn/nqz306_bib13 article-title: A randomized placebo-controlled trial of the effect of coffee consumption on insulin sensitivity: design and baseline characteristics of the Coffee for METabolic Health (COMETH) study publication-title: Contemp Clin Trials Commun. doi: 10.1016/j.conctc.2016.06.013 – volume: 49 start-page: 27 issue: 1 year: 2012 ident: 10.1093/ajcn/nqz306_bib43 article-title: Cafestol extraction yield from different coffee brew mechanisms publication-title: Food Res Int. doi: 10.1016/j.foodres.2012.06.032 – volume: 27 start-page: 2990 issue: 12 year: 2004 ident: 10.1093/ajcn/nqz306_bib7 article-title: Effects of coffee consumption on fasting blood glucose and insulin concentrations: randomized controlled trials in healthy volunteers publication-title: Diabetes Care. doi: 10.2337/diacare.27.12.2990 – volume: 48 start-page: 887 issue: 4 year: 1994 ident: 10.1093/ajcn/nqz306_bib40 article-title: The effect of caffeine on food intake in rats: involvement of corticotropin-releasing factor and the sympatho-adrenal system publication-title: Pharmacol Biochem Behav. doi: 10.1016/0091-3057(94)90196-1 – volume: 43 start-page: 2167 issue: 8 year: 1995 ident: 10.1093/ajcn/nqz306_bib44 article-title: Levels of the cholesterol-elevating diterpenes cafestol and kahweol in various coffee brews publication-title: J Agric Food Chem. doi: 10.1021/jf00056a039 – volume: 31 start-page: 565 issue: 4 year: 1991 ident: 10.1093/ajcn/nqz306_bib54 article-title: Effects of hydration and dehydration on body composition analysis: a comparative study of bioelectric impedance analysis and hydrodensitometry publication-title: J Sports Med Phys Fitness. – start-page: 155 year: 1998 ident: 10.1093/ajcn/nqz306_bib18 article-title: Coefficient of variation – volume: 340 start-page: c869 year: 2010 ident: 10.1093/ajcn/nqz306_bib22 article-title: CONSORT 2010 explanation and elaboration: updated guidelines for reporting parallel group randomised trials publication-title: Br Med J. doi: 10.1136/bmj.c869 – volume: 103 start-page: 1370 issue: 5 year: 2016 ident: 10.1093/ajcn/nqz306_bib29 article-title: Coffee and tea consumption in relation to estimated glomerular filtration rate: results from the population-based longitudinal Doetinchem Cohort Study publication-title: Am J Clin Nutr. doi: 10.3945/ajcn.115.112755 – volume: 27 start-page: 1487 issue: 6 year: 2004 ident: 10.1093/ajcn/nqz306_bib16 article-title: Use and abuse of HOMA modeling publication-title: Diabetes Care. doi: 10.2337/diacare.27.6.1487 – volume: 65 start-page: 717 issue: 3 year: 1980 ident: 10.1093/ajcn/nqz306_bib26 article-title: Epinephrine-induced insulin resistance in man publication-title: J Clin Invest. doi: 10.1172/JCI109718 – ident: 10.1093/ajcn/nqz306_bib46 – volume: 51 start-page: 759 issue: 5 year: 1990 ident: 10.1093/ajcn/nqz306_bib37 article-title: Caffeine: a double-blind, placebo-controlled study of its thermogenic, metabolic, and cardiovascular effects in healthy volunteers publication-title: Am J Clin Nutr. doi: 10.1093/ajcn/51.5.759 – volume: 1 start-page: 23 issue: 1 year: 2011 ident: 10.1093/ajcn/nqz306_bib6 article-title: Caffeine, glucose metabolism, and type 2 diabetes publication-title: J Caffeine Res. doi: 10.1089/jcr.2010.0007 – volume: 18 start-page: 345 issue: 5 year: 1994 ident: 10.1093/ajcn/nqz306_bib39 article-title: Relationship between basal metabolic rate, thermogenic response to caffeine, and body weight loss following combined low calorie and exercise treatment in obese women publication-title: Int J Obes Relat Metab Disord. – year: 2015 ident: 10.1093/ajcn/nqz306_bib1 – volume: 88 start-page: 979 issue: 4 year: 2008 ident: 10.1093/ajcn/nqz306_bib49 article-title: Coffee, tea, and incident type 2 diabetes: the Singapore Chinese Health Study publication-title: Am J Clin Nutr. doi: 10.1093/ajcn/88.4.979 – volume: 42 start-page: 880 issue: 4 year: 2018 ident: 10.1093/ajcn/nqz306_bib30 article-title: Habitual coffee consumption and changes in measures of adiposity: a comprehensive study of longitudinal associations publication-title: Int J Obes (Lond). doi: 10.1038/ijo.2017.310 – volume: 54 start-page: 845 issue: 5 year: 2015 ident: 10.1093/ajcn/nqz306_bib10 article-title: Cardiometabolic effects of two coffee blends differing in content for major constituents in overweight adults: a randomized controlled trial publication-title: Eur J Nutr. doi: 10.1007/s00394-014-0763-3 – start-page: 43 year: 2007 ident: 10.1093/ajcn/nqz306_bib51 article-title: Glucose clamp techniques – volume: 50 start-page: 2349 issue: 10 year: 2001 ident: 10.1093/ajcn/nqz306_bib24 article-title: Caffeine ingestion decreases glucose disposal during a hyperinsulinemic-euglycemic clamp in sedentary humans publication-title: Diabetes. doi: 10.2337/diabetes.50.10.2349 – volume: 15 start-page: 403 issue: 10 year: 2013 ident: 10.1093/ajcn/nqz306_bib41 article-title: Coffee consumption and cardiovascular health: getting to the heart of the matter publication-title: Curr Cardiol Rep. doi: 10.1007/s11886-013-0403-1 – volume: 10 start-page: 93 year: 2011 ident: 10.1093/ajcn/nqz306_bib11 article-title: Effects of caffeinated and decaffeinated coffee on biological risk factors for type 2 diabetes: a randomized controlled trial publication-title: Nutr J. doi: 10.1186/1475-2891-10-93 – volume: 35 start-page: 1381 issue: 8 year: 2003 ident: 10.1093/ajcn/nqz306_bib20 article-title: International physical activity questionnaire: 12-country reliability and validity publication-title: Med Sci Sports Exerc. doi: 10.1249/01.MSS.0000078924.61453.FB – volume: 10 start-page: 48 year: 2011 ident: 10.1093/ajcn/nqz306_bib45 article-title: Cholesterol-raising diterpenes in types of coffee commonly consumed in Singapore, Indonesia and India and associations with blood lipids: a survey and cross sectional study publication-title: Nutr J. doi: 10.1186/1475-2891-10-48 – volume: 91 start-page: 950 issue: 4 year: 2010 ident: 10.1093/ajcn/nqz306_bib9 article-title: Effects of coffee consumption on subclinical inflammation and other risk factors for type 2 diabetes: a clinical trial publication-title: Am J Clin Nutr. doi: 10.3945/ajcn.2009.28548 – reference: 31919498 - Am J Clin Nutr. 2020 Feb 1;111(2):248-249 |
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| Snippet | In observational studies, coffee consumption has been consistently associated with a lower risk of type 2 diabetes mellitus. Trials examining the effect of... ABSTRACT Background In observational studies, coffee consumption has been consistently associated with a lower risk of type 2 diabetes mellitus. Trials... Background In observational studies, coffee consumption has been consistently associated with a lower risk of type 2 diabetes mellitus. Trials examining the... |
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| SubjectTerms | Adiponectin Adult adult-onset diabetes mellitus Aged Body fat Body weight Coffee Consumption Creatinine Cups Diabetes Diabetes mellitus Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 2 Fasting Female Females Glucose Glucose metabolism Health risks Humans hyperinsulinemic euglycemic clamp Insulin Insulin - metabolism Insulin Resistance insulin sensitivity Male Males metabolic health Metabolism Middle Aged Overweight Randomization Reduction Risk analysis Risk Factors Sensitivity type 2 diabetes |
| Title | The effect of coffee consumption on insulin sensitivity and other biological risk factors for type 2 diabetes: a randomized placebo-controlled trial |
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