Association Between Prekallikrein and Stroke: A Mendelian Randomization Study

• Published in: Journal of the American Heart Association Vol. 12; no. 16; p. e030525
• Main Authors: Wang, Yinan, Jia, Yiming, Xu, Qingyun, Yang, Pinni, Sun, Lulu, Liu, Yi, Chang, Xinyue, He, Yu, Shi, Mengyao, Guo, Daoxia, Zhang, Yonghong, Zhu, Zhengbao
• Format: Journal Article
• Language: English
• Published: England John Wiley and Sons Inc 15.08.2023; Wiley
• Subjects: ischemic stroke; Mendelian randomization; Original Research; prekallikrein; stroke; Mendelian randomization; prekallikrein; stroke; ischemic stroke

Background High plasma prekallikrein was reported to be associated with increased risks of stroke, but the causality for these associations remains unclear. We aimed to investigate the associations of genetically predicted plasma prekallikrein concentrations with all-cause stroke, ischemic stroke, 3...