Neuroprotective and anti-inflammatory effects of eicosane on glutamate and NMDA-induced retinal ganglion cell injury

• Published in: International journal of ophthalmology Vol. 17; no. 4; pp. 638 - 645
• Main Authors: Wu, Zhen-Kai, Zhu, You-Lin, Xiong, Meng-Qin, Zhong, Jing-Xiang
• Format: Journal Article
• Language: English
• Published: China International Journal of Ophthalmology Press 18.04.2024; Press of International Journal of Ophthalmology (IJO PRESS)
• Subjects: Basic Research; eicosane; glaucoma; metabolites; metabolites; glaucoma; eicosane

AIM: To investigate the protective effects, antioxidant potential, and anti-inflammatory mechanisms of eicosane on glutamate-induced cell damage and on N-methyl-D-aspartate (NMDA)-induced retinal ganglion cell (RGC) injury in a mouse model of glaucoma. METHODS: The protective effects of eicosane on...