Sulfoacetate generated by Rhodopseudomonas palustris from taurine

• Published in: Archives of microbiology Vol. 182; no. 2-3; pp. 254 - 258
• Main Authors: DENGER, Karin, WEINITSCHKE, Sonja, HOLLEMEYER, Klaus, COOK, Alasdair M
• Format: Journal Article
• Language: English
• Published: Heidelberg Springer 01.10.2004; Berlin Springer Nature B.V
• Subjects: Acetaldehyde - analogs & derivatives; Acetaldehyde - metabolism; Acetates - analysis; Acetates - metabolism; Aldehyde Oxidoreductases - metabolism; Bacteria; Bacteriology; Betaine-Aldehyde Dehydrogenase; Biological and medical sciences; Fundamental and applied biological sciences. Psychology; Mass spectrometry; Microbiology; Miscellaneous; Natural products; Rhodopseudomonas - metabolism; Rhodopseudomonas palustris; Sulfates - metabolism; Taurine - metabolism; Microbiology; Enzyme; Rhodopseudomonas palustris; Rhodospirillaceae; Dehydrogenase; Sulfoacetaldehyde dehydrogenase; Rhodospirillales; Taurine dehydrogenase; Sulfoacetate formation; Bacteria; Oxidoreductases; Taurine deamination; Rhodospirillineae
• ISSN: 0302-8933; 1432-072X
• DOI: 10.1007/s00203-004-0678-0

Genes thought to encode (a) the regulator of taurine catabolism under carbon-limiting or nitrogen-limiting conditions and (b) taurine dehydrogenase were found in the genome of Rhodopseudomonas palustris. The organism utilized taurine quantitatively as a sole source of nitrogen (but not of carbon) for aerobic and photoheterotrophic growth. No sulfate was released, and the C-sulfonate bond was recovered stoichiometrically as sulfoacetate, which was identified by mass spectrometry. An inducible sulfoacetaldehyde dehydrogenase was detected. R. palustris thus contains a pathway to generate a natural product that was previously believed to be formed solely from sulfoquinovose.