Decreased cathepsin V expression due to Fli1 deficiency contributes to the development of dermal fibrosis and proliferative vasculopathy in systemic sclerosis - Noda, S.; Asano, Y.; Takahashi, T.; Akamata, K.; Aozasa, N.; Taniguchi, T.; Ichimura, Y.; Toyama, T.; Sumida, H.; Kuwano, Y.; Yanaba, K.; Tada, Y.; et al. (Rheumatology (Oxford, England), 2013)
Keywords: Adult; Aged; Biopsy, Needle; Case-Control Studies; Cathepsins - genetics; Cathepsins - metabolism; Cysteine Endopeptidases - genetics; Cysteine Endopeptidases - metabolism; Disease Progression; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Female; Fibrosis - genetics; Fibrosis - pathology; Gene Expression Regulation; Humans; Immunohistochemistry; Male; Middle Aged; Neovascularization, Pathologic - genetics; Neovascularization, Pathologic - pathology; Prognosis; Proto-Oncogene Protein c-fli-1 - deficiency; Real-Time Polymerase Chain Reaction; Reference Values; RNA - metabolism; Scleroderma, Diffuse - genetics; Scleroderma, Diffuse - pathology; Scleroderma, Systemic - blood; Scleroderma, Systemic - genetics; Scleroderma, Systemic - pathology; Sensitivity and Specificity; Severity of Illness Index