Prediction of protein structure from ideal forms

• Published in: Proteins, structure, function, and bioinformatics Vol. 70; no. 4; pp. 1610 - 1619
• Main Authors: Taylor, William R., Bartlett, Gail J., Chelliah, Vijayalakshmi, Klose, Daniel, Lin, Kuang, Sheldon, Tom, Jonassen, Inge
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.03.2008; Wiley
• Subjects: Amino Acid Sequence; combinatorial method; Databases, Protein; Models, Molecular; Molecular Weight; Protein Conformation; Protein Folding; protein structure prediction; Proteins; Proteins - chemistry

For many years it has been accepted that the sequence of a protein can specify its three‐dimensional structure. However, there has been limited progress in explaining how the sequence dictates its fold and no attempt to do this computationally without the use of specific structural data has ever suc...