Vitamin D and immune function: an overview

• Published in: Proceedings of the Nutrition Society Vol. 71; no. 1; pp. 50 - 61
• Main Author: Hewison, Martin
• Format: Journal Article
• Language: English
• Published: Cambridge, UK Cambridge University Press 01.02.2012
• Subjects: adaptive immunity; Autoimmune diseases; Autoimmune Diseases - blood; Autoimmune Diseases - etiology; Crohn disease; dendritic cells; Dendritic Cells - physiology; epidemiological studies; Health problems; human physiology; Human subjects; Humans; Immune response; Immune system; Immunity - physiology; Immunologic Factors - metabolism; immunomodulation; Infection - blood; Infection - etiology; Inflammatory bowel disease; insulin-dependent diabetes mellitus; Lymphocytes; macrophages; Macrophages - physiology; Metabolites; Mycobacterium; Nutrition; pathogens; Rodents; sclerosis; Symposium 3: Vitamin D and immune function: from pregnancy to adolescence; T-Lymphocytes; Tuberculosis; Vitamin D; Vitamin D - analogs & derivatives; Vitamin D - immunology; Vitamin D - metabolism; Vitamin D Deficiency - blood; Vitamin D Deficiency - complications; Vitamin D Deficiency - immunology; vitamin deficiencies; Vitamin deficiency; Innate immunity; Adaptive immunity; Antibacterial; Vitamin D

Immunomodulatory actions of vitamin D have been recognised for over a quarter of a century, but it is only in the last few years that the significance of this to normal human physiology has become apparent. Two key factors have underpinned this revised perspective. Firstly, there are increasing data...