EEG-LORETA endophenotypes of the common idiopathic generalized epilepsy syndromes

• Published in: Epilepsy research Vol. 99; no. 3; pp. 281 - 292
• Main Authors: Clemens, B, Puskás, S, Besenyei, M, Emri, M, Opposits, G, Kis, S.A, Hollódy, K, Fogarasi, A, Kondákor, I, Füle, K, Bense, K, Fekete, I
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier B.V 01.05.2012; Elsevier
• Subjects: Absence; Adolescent; Anticonvulsants. Antiepileptics. Antiparkinson agents; Biological and medical sciences; EEG; Electroencephalography - methods; Electromagnetic Phenomena; Endophenotype; Endophenotypes; Epilepsy, Generalized - diagnosis; Epilepsy, Generalized - physiopathology; Female; Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy; Humans; Juvenile myoclonic epilepsy; LORETA; Male; Medical sciences; Nervous system (semeiology, syndromes); Neurology; Neuropharmacology; Pharmacology. Drug treatments; Tomography - methods; Young Adult; Absence; LORETA; Juvenile myoclonic epilepsy; EEG; Endophenotype; Nervous system diseases; Epilepsy; Central nervous system disease; Idiopathic; Electrophysiology; Electroencephalography; Cerebral disorder

Summary Objective We tested the hypothesis that the cortical areas with abnormal local EEG synchronization are dissimilar in the three common idiopathic generalized epilepsy (IGE) phenotypes: IGE patients with absence seizures (ABS), juvenile myoclonic epilepsy (JME) and epilepsy with generalized to...