EEG-LORETA endophenotypes of the common idiopathic generalized epilepsy syndromes
Summary Objective We tested the hypothesis that the cortical areas with abnormal local EEG synchronization are dissimilar in the three common idiopathic generalized epilepsy (IGE) phenotypes: IGE patients with absence seizures (ABS), juvenile myoclonic epilepsy (JME) and epilepsy with generalized to...
Saved in:
Published in | Epilepsy research Vol. 99; no. 3; pp. 281 - 292 |
---|---|
Main Authors | , , , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Kidlington
Elsevier B.V
01.05.2012
Elsevier |
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | Summary Objective We tested the hypothesis that the cortical areas with abnormal local EEG synchronization are dissimilar in the three common idiopathic generalized epilepsy (IGE) phenotypes: IGE patients with absence seizures (ABS), juvenile myoclonic epilepsy (JME) and epilepsy with generalized tonic–clonic seizures exclusively (EGTCS). Patients and methods Groups of unmedicated ABS, JME and EGTCS patients were investigated. Waking EEG background activity (without any epileptiform potentials) was analyzed by a source localization method, LORETA (Low Resolution Electromagnetic Tomography). Each patient group was compared to a separate, age-matched group of healthy control persons. Voxel-based, normalized broad-band (delta, theta, alpha, and beta) and very narrow band (VNB, 1 Hz bandwidth, from 1 to 25 Hz) LORETA activity (=current source density, A/m2 ) were computed for each person. Group comparison included subtraction (average patient data minus average control data) and group statistics (multiple t -tests, where Bonferroni-corrected p < 0.05 values were accepted as statistically significant). Results Statistically not significant main findings were: overall increased delta and theta broad band activity in the ABS and JME groups; decrease of alpha and beta activity in the EGTCS group. Statistically significant main findings were as follows. JME group : bilaterally increased theta activity in posterior (temporal, parietal, and occipital) cortical areas; bilaterally increased activity in the medial and basal prefrontal area in the 8 Hz VNB; bilaterally decreased activity in the precuneus, posterior cingulate and superior parietal lobule in the 11 Hz and 21–22 Hz VNBs. ABS group : bilaterally increased theta activity emerged in the basal prefrontal and medial temporal limbic areas. Decreased activity was found at 19–21 Hz in the right postcentral gyrus and parts of the right superior and medial temporal gyri. EGTCS group : decreased activity was found in the frontal cortex and the postcentral gyrus at 10–11 Hz, increased activity in the right parahippocampal gyrus at 16–18 Hz. Discussion Increased theta activity in the posterior parts of the cortex is the endophenotype for JME. Increased theta activity in the fronto-temporal limbic areas is the endophenotype for ABS. Statistically not significant findings might indicate diffuse biochemical abnormality of the cortex in JME and ABS. Significance EEG-LORETA endophenotypes may correspond to the selective propensity to generate absence and myoclonic seizures in the ABS and JME syndromes. |
---|---|
AbstractList | Summary Objective We tested the hypothesis that the cortical areas with abnormal local EEG synchronization are dissimilar in the three common idiopathic generalized epilepsy (IGE) phenotypes: IGE patients with absence seizures (ABS), juvenile myoclonic epilepsy (JME) and epilepsy with generalized tonic–clonic seizures exclusively (EGTCS). Patients and methods Groups of unmedicated ABS, JME and EGTCS patients were investigated. Waking EEG background activity (without any epileptiform potentials) was analyzed by a source localization method, LORETA (Low Resolution Electromagnetic Tomography). Each patient group was compared to a separate, age-matched group of healthy control persons. Voxel-based, normalized broad-band (delta, theta, alpha, and beta) and very narrow band (VNB, 1 Hz bandwidth, from 1 to 25 Hz) LORETA activity (=current source density, A/m2 ) were computed for each person. Group comparison included subtraction (average patient data minus average control data) and group statistics (multiple t -tests, where Bonferroni-corrected p < 0.05 values were accepted as statistically significant). Results Statistically not significant main findings were: overall increased delta and theta broad band activity in the ABS and JME groups; decrease of alpha and beta activity in the EGTCS group. Statistically significant main findings were as follows. JME group : bilaterally increased theta activity in posterior (temporal, parietal, and occipital) cortical areas; bilaterally increased activity in the medial and basal prefrontal area in the 8 Hz VNB; bilaterally decreased activity in the precuneus, posterior cingulate and superior parietal lobule in the 11 Hz and 21–22 Hz VNBs. ABS group : bilaterally increased theta activity emerged in the basal prefrontal and medial temporal limbic areas. Decreased activity was found at 19–21 Hz in the right postcentral gyrus and parts of the right superior and medial temporal gyri. EGTCS group : decreased activity was found in the frontal cortex and the postcentral gyrus at 10–11 Hz, increased activity in the right parahippocampal gyrus at 16–18 Hz. Discussion Increased theta activity in the posterior parts of the cortex is the endophenotype for JME. Increased theta activity in the fronto-temporal limbic areas is the endophenotype for ABS. Statistically not significant findings might indicate diffuse biochemical abnormality of the cortex in JME and ABS. Significance EEG-LORETA endophenotypes may correspond to the selective propensity to generate absence and myoclonic seizures in the ABS and JME syndromes. We tested the hypothesis that the cortical areas with abnormal local EEG synchronization are dissimilar in the three common idiopathic generalized epilepsy (IGE) phenotypes: IGE patients with absence seizures (ABS), juvenile myoclonic epilepsy (JME) and epilepsy with generalized tonic–clonic seizures exclusively (EGTCS). Groups of unmedicated ABS, JME and EGTCS patients were investigated. Waking EEG background activity (without any epileptiform potentials) was analyzed by a source localization method, LORETA (Low Resolution Electromagnetic Tomography). Each patient group was compared to a separate, age-matched group of healthy control persons. Voxel-based, normalized broad-band (delta, theta, alpha, and beta) and very narrow band (VNB, 1Hz bandwidth, from 1 to 25Hz) LORETA activity (=current source density, A/m2) were computed for each person. Group comparison included subtraction (average patient data minus average control data) and group statistics (multiple t-tests, where Bonferroni-corrected p<0.05 values were accepted as statistically significant). Statistically not significant main findings were: overall increased delta and theta broad band activity in the ABS and JME groups; decrease of alpha and beta activity in the EGTCS group. Statistically significant main findings were as follows. JME group: bilaterally increased theta activity in posterior (temporal, parietal, and occipital) cortical areas; bilaterally increased activity in the medial and basal prefrontal area in the 8Hz VNB; bilaterally decreased activity in the precuneus, posterior cingulate and superior parietal lobule in the 11Hz and 21–22Hz VNBs. ABS group: bilaterally increased theta activity emerged in the basal prefrontal and medial temporal limbic areas. Decreased activity was found at 19–21Hz in the right postcentral gyrus and parts of the right superior and medial temporal gyri. EGTCS group: decreased activity was found in the frontal cortex and the postcentral gyrus at 10–11Hz, increased activity in the right parahippocampal gyrus at 16–18Hz. Increased theta activity in the posterior parts of the cortex is the endophenotype for JME. Increased theta activity in the fronto-temporal limbic areas is the endophenotype for ABS. Statistically not significant findings might indicate diffuse biochemical abnormality of the cortex in JME and ABS. EEG-LORETA endophenotypes may correspond to the selective propensity to generate absence and myoclonic seizures in the ABS and JME syndromes. OBJECTIVEWe tested the hypothesis that the cortical areas with abnormal local EEG synchronization are dissimilar in the three common idiopathic generalized epilepsy (IGE) phenotypes: IGE patients with absence seizures (ABS), juvenile myoclonic epilepsy (JME) and epilepsy with generalized tonic-clonic seizures exclusively (EGTCS).PATIENTS AND METHODSGroups of unmedicated ABS, JME and EGTCS patients were investigated. Waking EEG background activity (without any epileptiform potentials) was analyzed by a source localization method, LORETA (Low Resolution Electromagnetic Tomography). Each patient group was compared to a separate, age-matched group of healthy control persons. Voxel-based, normalized broad-band (delta, theta, alpha, and beta) and very narrow band (VNB, 1Hz bandwidth, from 1 to 25Hz) LORETA activity (=current source density, A/m(2)) were computed for each person. Group comparison included subtraction (average patient data minus average control data) and group statistics (multiple t-tests, where Bonferroni-corrected p<0.05 values were accepted as statistically significant).RESULTSStatistically not significant main findings were: overall increased delta and theta broad band activity in the ABS and JME groups; decrease of alpha and beta activity in the EGTCS group. Statistically significant main findings were as follows. JME group: bilaterally increased theta activity in posterior (temporal, parietal, and occipital) cortical areas; bilaterally increased activity in the medial and basal prefrontal area in the 8Hz VNB; bilaterally decreased activity in the precuneus, posterior cingulate and superior parietal lobule in the 11Hz and 21-22Hz VNBs. ABS group: bilaterally increased theta activity emerged in the basal prefrontal and medial temporal limbic areas. Decreased activity was found at 19-21Hz in the right postcentral gyrus and parts of the right superior and medial temporal gyri. EGTCS group: decreased activity was found in the frontal cortex and the postcentral gyrus at 10-11Hz, increased activity in the right parahippocampal gyrus at 16-18Hz.DISCUSSIONIncreased theta activity in the posterior parts of the cortex is the endophenotype for JME. Increased theta activity in the fronto-temporal limbic areas is the endophenotype for ABS. Statistically not significant findings might indicate diffuse biochemical abnormality of the cortex in JME and ABS.SIGNIFICANCEEEG-LORETA endophenotypes may correspond to the selective propensity to generate absence and myoclonic seizures in the ABS and JME syndromes. We tested the hypothesis that the cortical areas with abnormal local EEG synchronization are dissimilar in the three common idiopathic generalized epilepsy (IGE) phenotypes: IGE patients with absence seizures (ABS), juvenile myoclonic epilepsy (JME) and epilepsy with generalized tonic-clonic seizures exclusively (EGTCS). Groups of unmedicated ABS, JME and EGTCS patients were investigated. Waking EEG background activity (without any epileptiform potentials) was analyzed by a source localization method, LORETA (Low Resolution Electromagnetic Tomography). Each patient group was compared to a separate, age-matched group of healthy control persons. Voxel-based, normalized broad-band (delta, theta, alpha, and beta) and very narrow band (VNB, 1Hz bandwidth, from 1 to 25Hz) LORETA activity (=current source density, A/m(2)) were computed for each person. Group comparison included subtraction (average patient data minus average control data) and group statistics (multiple t-tests, where Bonferroni-corrected p<0.05 values were accepted as statistically significant). Statistically not significant main findings were: overall increased delta and theta broad band activity in the ABS and JME groups; decrease of alpha and beta activity in the EGTCS group. Statistically significant main findings were as follows. JME group: bilaterally increased theta activity in posterior (temporal, parietal, and occipital) cortical areas; bilaterally increased activity in the medial and basal prefrontal area in the 8Hz VNB; bilaterally decreased activity in the precuneus, posterior cingulate and superior parietal lobule in the 11Hz and 21-22Hz VNBs. ABS group: bilaterally increased theta activity emerged in the basal prefrontal and medial temporal limbic areas. Decreased activity was found at 19-21Hz in the right postcentral gyrus and parts of the right superior and medial temporal gyri. EGTCS group: decreased activity was found in the frontal cortex and the postcentral gyrus at 10-11Hz, increased activity in the right parahippocampal gyrus at 16-18Hz. Increased theta activity in the posterior parts of the cortex is the endophenotype for JME. Increased theta activity in the fronto-temporal limbic areas is the endophenotype for ABS. Statistically not significant findings might indicate diffuse biochemical abnormality of the cortex in JME and ABS. EEG-LORETA endophenotypes may correspond to the selective propensity to generate absence and myoclonic seizures in the ABS and JME syndromes. |
Author | Hollódy, K Füle, K Bense, K Kis, S.A Clemens, B Puskás, S Opposits, G Fogarasi, A Kondákor, I Fekete, I Besenyei, M Emri, M |
Author_xml | – sequence: 1 fullname: Clemens, B – sequence: 2 fullname: Puskás, S – sequence: 3 fullname: Besenyei, M – sequence: 4 fullname: Emri, M – sequence: 5 fullname: Opposits, G – sequence: 6 fullname: Kis, S.A – sequence: 7 fullname: Hollódy, K – sequence: 8 fullname: Fogarasi, A – sequence: 9 fullname: Kondákor, I – sequence: 10 fullname: Füle, K – sequence: 11 fullname: Bense, K – sequence: 12 fullname: Fekete, I |
BackLink | http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=25884241$$DView record in Pascal Francis https://www.ncbi.nlm.nih.gov/pubmed/22240326$$D View this record in MEDLINE/PubMed |
BookMark | eNqNksFu1DAQhi1URLeFV0C-IHFJ8NiOk70glWopSJUQUM6Wa09YL4kd7CxSeHq87EIlTpx8-f6ZX9_4gpyFGJAQCqwGBurVrsZpwCkvCXPNGUANvGase0RW0LW8Up2UZ2TF1pxVwAHOyUXOO8ZYy6R8Qs4555IJrlbk42ZzU91--LS5u6IYXJy2GOK8TJhp7Om8RWrjOMZAvfNxMvPWW_oVAyYz-J_oKE7-dxGal-BSHDE_JY97M2R8dnovyZe3m7vrd2XLzfvrq9vKymY9V2ilADCyl6prnbpvjOsYGGAS27UwyirRoHLYgkLHJXBkQsC6MSCsMD0Xl-Tlce6U4vc95lmPPlscBhMw7rMuoliZwVVT0O6I2hRzTtjrKfnRpKVAB07pnX4Qqg9CNXBdhJbo89OW_f2I7m_wj8ECvDgBJlsz9MkE6_MD13SdLPUL9-bIYXHyw2PS2XoMFp1PaGftov-fNq__GWIHH3zZ-w0XzLu4T6E416BzCejPhw9wuD8AYxIaIX4BShGvUw |
CODEN | EPIRE8 |
CitedBy_id | crossref_primary_10_1016_j_eplepsyres_2017_03_006 crossref_primary_10_1016_j_clinph_2022_11_004 crossref_primary_10_1038_srep28867 crossref_primary_10_1177_1550059413506001 crossref_primary_10_1016_j_jneumeth_2020_108740 crossref_primary_10_1212_WNL_0000000000012144 crossref_primary_10_1177_23727322221108508 crossref_primary_10_3389_fnins_2020_00196 crossref_primary_10_1016_j_bspc_2021_102554 crossref_primary_10_1186_s12883_022_02577_6 crossref_primary_10_1016_j_seizure_2019_04_007 crossref_primary_10_1016_j_eplepsyres_2020_106324 crossref_primary_10_1159_000495522 crossref_primary_10_1016_j_clinph_2021_06_012 |
Cites_doi | 10.1016/j.neuroimage.2008.12.011 10.1016/j.neuroimage.2007.06.025 10.1016/j.neuroimage.2007.08.020 10.1093/brain/121.9.1661 10.1111/j.0013-9580.2004.23204.x 10.1016/S1053-8119(03)00204-0 10.1111/j.1528-1157.1998.tb01388.x 10.1186/gm184 10.1016/j.neuroscience.2003.08.051 10.1023/A:1012996930489 10.1016/S1388-2457(99)00122-4 10.1097/01.wco.0000137539.91738.2b 10.1523/JNEUROSCI.22-04-01480.2002 10.1016/0140-6736(92)91679-3 10.1016/j.neuroimage.2010.03.037 10.1111/j.1528-1157.1979.tb04840.x 10.1684/j.1950-6945.2004.tb00054.x 10.1016/j.eplepsyres.2011.03.008 10.1046/j.1528-1157.2002.26901.x 10.1097/00004691-199004000-00003 10.1016/j.eplepsyres.2010.07.001 10.1002/ana.69 10.1111/j.1528-1167.2007.01381.x 10.1111/j.1528-1157.1983.tb04880.x 10.1212/01.wnl.0000336969.98241.17 10.1007/s00415-008-0745-6 10.1016/0013-4694(74)90031-5 10.1016/j.neuroimage.2009.08.004 10.1016/j.eplepsyres.2009.12.004 10.1016/0167-8760(84)90014-X 10.1055/s-0028-1094604 10.1016/j.eplepsyres.2009.03.015 10.1111/j.1528-1167.2009.02198.x 10.1016/j.seizure.2007.07.005 10.1016/0013-4694(94)90011-6 10.1684/j.1950-6945.2006.tb00204.x 10.1212/WNL.27.4.326 10.1038/ejhg.2008.267 10.1086/426735 10.1111/j.1528-1157.1989.tb05316.x 10.1212/WNL.61.11.1576 10.1523/JNEUROSCI.13-11-04622.1993 10.1136/jnnp.74.1.51 10.1111/j.1528-1157.1984.tb04149.x 10.1038/sj.jcbfm.9600300 10.1111/j.1528-1167.2008.01509.x 10.1016/S0920-1211(00)00167-4 10.1073/pnas.0701361104 10.1016/j.neuroimage.2003.09.051 10.1111/j.1528-1167.2008.01724.x 10.1111/j.1528-1167.2010.02698.x 10.1007/BF01187711 10.1111/j.1528-1157.2000.tb00158.x 10.1002/ana.410430405 10.1212/WNL.0b013e318203e93d 10.1016/j.neuroimage.2006.04.174 10.1212/WNL.0b013e3181f11c06 10.1002/ana.410340308 10.1016/j.neuroimage.2007.10.058 10.1016/j.biopsycho.2007.01.004 10.1097/00004691-199004000-00004 10.1111/j.1528-1157.1997.tb01467.x 10.1002/hbm.20032 10.1146/annurev.physiol.63.1.815 10.1177/155005949702800403 10.1002/hbm.20323 10.1093/brain/122.11.2101 10.1111/j.1528-1167.2009.02180.x 10.1016/j.brainres.2007.10.048 10.1016/0014-4886(86)90122-6 10.1016/0013-4694(85)90005-7 10.1111/j.1528-1167.2007.01030.x 10.1111/j.1528-1167.2008.01948.x 10.1016/S0165-0173(98)00056-3 10.1007/BF00201587 10.1016/j.clinph.2006.11.016 10.1016/S0079-6123(05)50011-6 10.1111/j.0013-9580.2004.46803.x |
ContentType | Journal Article |
Copyright | Elsevier B.V. 2011 Elsevier B.V. 2015 INIST-CNRS Copyright © 2011 Elsevier B.V. All rights reserved. |
Copyright_xml | – notice: Elsevier B.V. – notice: 2011 Elsevier B.V. – notice: 2015 INIST-CNRS – notice: Copyright © 2011 Elsevier B.V. All rights reserved. |
DBID | IQODW CGR CUY CVF ECM EIF NPM AAYXX CITATION 7X8 |
DOI | 10.1016/j.eplepsyres.2011.12.008 |
DatabaseName | Pascal-Francis Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef MEDLINE - Academic |
DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef MEDLINE - Academic |
DatabaseTitleList | MEDLINE - Academic MEDLINE |
Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine Pharmacy, Therapeutics, & Pharmacology |
EISSN | 1872-6844 |
EndPage | 292 |
ExternalDocumentID | 10_1016_j_eplepsyres_2011_12_008 22240326 25884241 S0920121111004153 1_s2_0_S0920121111004153 |
Genre | Journal Article |
GroupedDBID | --- --K --M .1- .FO .~1 0R~ 1B1 1P~ 1RT 1~. 1~5 29G 4.4 457 4G. 53G 5GY 5VS 7-5 71M 8P~ 9JM AACTN AAEDT AAEDW AAIKJ AAKOC AALRI AAOAW AAQFI AAQXK AAXKI AAXLA AAXUO ABBQC ABCQJ ABFNM ABFRF ABJNI ABMAC ABMZM ABTEW ABXDB ACDAQ ACGFO ACGFS ACIUM ACRLP ADBBV ADEZE ADMUD AEBSH AEFWE AEKER AENEX AEVXI AFCTW AFJKZ AFKWA AFRHN AFTJW AFXIZ AGHFR AGUBO AGWIK AGYEJ AHHHB AIEXJ AIKHN AITUG AJOXV AJRQY AJUYK AKRLJ AKRWK ALMA_UNASSIGNED_HOLDINGS AMFUW AMRAJ ANZVX ASPBG AVWKF AXJTR AZFZN BKOJK BLXMC BNPGV CS3 DU5 EBS EFJIC EJD EO8 EO9 EP2 EP3 F5P FDB FEDTE FGOYB FIRID FNPLU FYGXN G-2 G-Q GBLVA HDW HMK HMO HMQ HVGLF HZ~ IHE J1W K-O KOM L7B LX8 M29 M2V M41 MO0 MOBAO N9A O-L O9- OAUVE OP~ OZT P-8 P-9 P2P PC. Q38 R2- RIG ROL RPZ SAE SCC SDF SDG SEL SES SEW SNS SPCBC SSH SSN SSZ T5K UNMZH WUQ Z5R ~G- AADPK AAIAV ABLVK ABYKQ AJBFU EFLBG LCYCR AAPBV ABPIF ABPTK IQODW CGR CUY CVF ECM EIF NPM AAYXX CITATION 7X8 |
ID | FETCH-LOGICAL-c459t-ec4311a4f4687d6b5ad801a104e793a6c635e6de716ed2412e033195a13c3af23 |
IEDL.DBID | .~1 |
ISSN | 0920-1211 |
IngestDate | Sat Aug 17 03:46:58 EDT 2024 Thu Sep 26 16:46:32 EDT 2024 Sat Sep 28 07:59:38 EDT 2024 Sun Oct 22 16:06:23 EDT 2023 Fri Feb 23 02:30:57 EST 2024 Tue Oct 15 22:55:50 EDT 2024 |
IsPeerReviewed | true |
IsScholarly | true |
Issue | 3 |
Keywords | Absence LORETA Juvenile myoclonic epilepsy EEG Endophenotype Nervous system diseases Epilepsy Central nervous system disease Idiopathic Electrophysiology Electroencephalography Cerebral disorder |
Language | English |
License | CC BY 4.0 Copyright © 2011 Elsevier B.V. All rights reserved. |
LinkModel | DirectLink |
MergedId | FETCHMERGED-LOGICAL-c459t-ec4311a4f4687d6b5ad801a104e793a6c635e6de716ed2412e033195a13c3af23 |
Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
PMID | 22240326 |
PQID | 1010635265 |
PQPubID | 23479 |
PageCount | 12 |
ParticipantIDs | proquest_miscellaneous_1010635265 crossref_primary_10_1016_j_eplepsyres_2011_12_008 pubmed_primary_22240326 pascalfrancis_primary_25884241 elsevier_sciencedirect_doi_10_1016_j_eplepsyres_2011_12_008 elsevier_clinicalkeyesjournals_1_s2_0_S0920121111004153 |
PublicationCentury | 2000 |
PublicationDate | 2012-05-01 |
PublicationDateYYYYMMDD | 2012-05-01 |
PublicationDate_xml | – month: 05 year: 2012 text: 2012-05-01 day: 01 |
PublicationDecade | 2010 |
PublicationPlace | Kidlington |
PublicationPlace_xml | – name: Kidlington – name: Netherlands |
PublicationTitle | Epilepsy research |
PublicationTitleAlternate | Epilepsy Res |
PublicationYear | 2012 |
Publisher | Elsevier B.V Elsevier |
Publisher_xml | – name: Elsevier B.V – name: Elsevier |
References | Greenberg, Cayanis, Strung, Marathe, Durner, Pal, Alvin, Klotz, Dicker, Shinnar, Bromfield, Resor, Cohen, Moshe, Harden, Kang (bib0145) 2005; 76 Aarabi, Wallois, Grebe (bib0005) 2008; 1188 Plummer, Harvey, Cook (bib0330) 2008; 49 Liu, Yang, Liao, Yang, Liu, Yan, Chen, Gong, Stefan, Zhou (bib0230) 2008; 49 Brandeis, Michel, Amzica (bib0060) 2009 Rodin (bib0360) 1984 Qiao, Noebels (bib0340) 1993; 13 Lüders, Najm, Nair, Widdess-Walsh, Bingman (bib0245) 2006; 8 Melø, Sonnewald, Touret, Nehlig (bib0275) 2006; 26 Steriade (bib0395) 2001; 86 Nuwer, Lehmann, Lopes da Silva, Matsuoka, Sutherling, Vibert (bib0300) 1994; 91 Grave de Peralta Menendez, Murray, Michel, Martuzzi, Gonzalez Andino (bib0140) 2004; 21 Reutens, Berkovic, Macdonell, Bladin (bib0350) 1993; 34 Szava, Valdes, Biscay, Galan, Bosch, Clark, Jimenez (bib0405) 1994; 6 Pascual-Marqui, Michel, Lehmann (bib0315) 1994; 18 Nair, Mohamed, Burgess, Lüders (bib0290) 2004; 6 Winawer, Rabinowitz, Pedley, Hauser, Ottman (bib0440) 2003; 61 Savic, Seitz, Pauli (bib0370) 1998; 39 Lüders, Awad (bib0240) 1991 Nunez (bib0295) 1995 Zietsch, Hansen, Hansell, Geffen, Martin, Wright (bib0455) 2007; 75 de Geus (bib0100) 2010; 2 Goh, Cusick, Valle, Childs, Vidal, Barabási (bib0130) 2007; 104 Pascual-Marqui (bib0320) 2002; 24 Marini, Scheffer, Crossland, Grinton, Phillips, McMahon, Turner, Dean, Kivity, Mazarib, Neufeld, Korczyn, Harkin, Dibbens, Wallace, Mulley, Berkovic (bib0250) 2004; 45 Carney, Masterton, Harvey, Scheffer, Berkovic, Jackson (bib0070) 2010; 75 Gotman (bib0135) 2008; 49 Savic, Lekwall, Greitz, Helms (bib0375) 2000; 41 Pascual-Marqui, Esslen, Kochi, Lehmann (bib0325) 2002; 30 Willoughby, Fitzgibbon, Pope, Mackenzie, Medvedev, Clark, Davey, Wilcox (bib0435) 2003; 74 Laufs, Hamandi, Salek-Haddadi, Kleinschmidt, Duncan, Lemieux (bib0220) 2007; 28 Strug, Clarke, Chiang, Chien, Baskurt, Li, Dorfman, Bali, Wirrell, Kugler, Mandelbaum, Wolf, McGoldrick, Hardison, Novotny, Ju, Greenberg, Russo, Pal (bib0400) 2009; 17 Berkovic, Howell, Hay, Hopper (bib0045) 1998; 43 O’Muircheartaigh, Vollmar, Barker, Kumari, Symms, Thompson, Duncan, Koepp, Richardson (bib0305) 2011; 76 Gloor, Metrakos, Metrakos, Andermann, van Gelder (bib0125) 1982 Lombroso (bib0235) 1997; 38 Puskás, Bessenyei, Fekete, Hollódy, Clemens (bib0335) 2010; 91 Bente (bib0040) 1979; 12 Holmes, Quiring, Tucker (bib0160) 2010; 49 Woermann, Sisodiya, Free, Duncan (bib0445) 1998; 121 Clemens, Bessenyei, Piros, Tóth, Seress, Kondákor (bib0080) 2007; 48 Deppe, Kellinghaus, Duning, Möddel, Mohammadi, Deppe, Schiffbauer, Kugel, Keller, Ringelstein, Knecht (bib0095) 2008; 71 Caplan, Levitt, Siddarth, Wu, Gurbani, Sankar, Shields (bib0065) 2009; 50 Kondacs, Szabo (bib0200) 1999; 110 Timofeev, Steriade (bib0415) 2004; 123 Attal, Bhattacharjee, Yelnik, Cottereau, Lefèvre, Okada, Bardinet, Chupin, Baillet (bib0025) 2007; 2007 ILAE (Commission on Classification and Terminology) (bib0170) 1989; 30 Meencke, Janz (bib0265) 1984; 25 Meeren, Pijn, Van Luijtelaar, Coenen, Lopes da Silva (bib0270) 2002; 22 van Beijsterveldt, Boomsma (bib0420) 1994; 94 Shackman, McMenamin, Maxwell, Greischar, Davidson (bib0380) 2010; 51 Koepp, Hamandi (bib0460) 2006 Hughes, Kaydanova (bib0165) 1997; 28 van Gelder, Siatitsas, Menini, Gloor (bib0425) 1983; 24 Woermann, Free, Koepp, Sisodiya, Duncan (bib0450) 1999; 122 Klimesch (bib0185) 1999; 29 Clemens, Szigeti, Barta (bib0075) 2000; 42 Clemens (bib0090) 2008; 17 Gloor, Ball, Schaul (bib0115) 1977; 4 Spencer (bib0385) 2002; 43 Panayiotopoulos (bib0310) 2005 Amor, Baillet, Navarro, Adam, Martinerie, Quyen (bib0015) 2009; 45 Moeller, Levan, Muhle, Stephani, Dubeau, Siniatchkin, Gotman (bib0285) 2010; 51 Sakurai, Takeda, Tanaka, Kurita, Shiraishi, Takeuchi, Nakane, Sueda, Koyama (bib0365) 2010; 89 Stefan, Paulini-Ruf, Hopfengärtner, Rampp (bib0390) 2009; 85 Kim, Lee, Koh, Lee, Lee, Kim, Kang (bib0180) 2007; 37 McCormick, Contreras (bib0260) 2001; 63 Kostopoulos (bib0205) 1986; 92 John (bib0175) 2005; 150 Moeller, Siebner, Wolff, Muhle, Boor, Granert, Jansen, Stephani, Siniatchkin (bib0280) 2008; 39 Vulliemoz, Vollmar, Koepp, Yogarajah, O’Muircheartaigh, Carmichael, Stretton, Richardson, Symms, Duncan (bib0430) 2010 Kozelka, Pedley (bib0210) 1990; 7 Gasser, Bacher, Steinberg (bib0110) 1985; 60 Koepp, Duncan (bib0195) 2004; 17 Lantz, Grave de Peralta Menendez, Gonzalez Andino, Michel (bib0215) 2001; 14 Anderson, Hamandi (bib0020) 2011 Durner, Mehdi, Keddache, Tomasini, Shinnar, Resor, Cohen, Harden, Moshe, Rosenbaum, Kang, Ballaben-Gil, Hertz, Labar, Luciano, Wallace, Yohai, Kloth, Dicker, Greenberg (bib0105) 2001; 49 Kobayashi, Grova, Tyvaert, Dubeau, Gotman (bib0190) 2009; 50 Robinson, Rennie, Rowe, O’ Connor (bib0355) 2004; 23 Blumenfeld, Westerveld, Ostroff, Vanderhill, Freeman, Necochea, Uranga, Tanhehco, Smith, Seibyl, Stokking, Studholme, Spencer, Zubal (bib0055) 2003; 19 Grova, Daunizeau, Kobayashi, Bagshaw, Lina, Dubeau, Gotman (bib0150) 2008; 39 Holmes, Brown, Tucker (bib0155) 2004; 45 Bancaud, Talairach, Morel, Bresson, Buser (bib0030) 1974; 37 Markand (bib0255) 1990; 7 Reutens, Berkovic (bib0345) 1992; 339 Gloor (bib0120) 1979; 20 Lin, Carrete, Lin, Peruchi, de Araújo Filho, Guaranha, Guilhoto, Sakamoto, Yacubian (bib0225) 2009; 50 Tae, Kim, Joo, Han, Kim, Kim, Lee, Hong (bib0410) 2008; 255 Aird, Masland, Woodbury (bib0010) 1984 Basar, Schürmann (bib0035) 1999; vol. II Betting, Mory, Li, Lopes-Cendes, Guerreiro, Guerreiro, Cendes (bib0050) 2006; 32 Clemens, Piros, Bessenyei, Hollódy (bib0085) 2007; 118 Gloor (10.1016/j.eplepsyres.2011.12.008_bib0120) 1979; 20 Grave de Peralta Menendez (10.1016/j.eplepsyres.2011.12.008_bib0140) 2004; 21 Stefan (10.1016/j.eplepsyres.2011.12.008_bib0390) 2009; 85 Tae (10.1016/j.eplepsyres.2011.12.008_bib0410) 2008; 255 Caplan (10.1016/j.eplepsyres.2011.12.008_bib0065) 2009; 50 Attal (10.1016/j.eplepsyres.2011.12.008_bib0025) 2007; 2007 Berkovic (10.1016/j.eplepsyres.2011.12.008_bib0045) 1998; 43 Hughes (10.1016/j.eplepsyres.2011.12.008_bib0165) 1997; 28 Marini (10.1016/j.eplepsyres.2011.12.008_bib0250) 2004; 45 Greenberg (10.1016/j.eplepsyres.2011.12.008_bib0145) 2005; 76 Szava (10.1016/j.eplepsyres.2011.12.008_bib0405) 1994; 6 John (10.1016/j.eplepsyres.2011.12.008_bib0175) 2005; 150 Moeller (10.1016/j.eplepsyres.2011.12.008_bib0280) 2008; 39 Steriade (10.1016/j.eplepsyres.2011.12.008_bib0395) 2001; 86 Bente (10.1016/j.eplepsyres.2011.12.008_bib0040) 1979; 12 Deppe (10.1016/j.eplepsyres.2011.12.008_bib0095) 2008; 71 Grova (10.1016/j.eplepsyres.2011.12.008_bib0150) 2008; 39 Pascual-Marqui (10.1016/j.eplepsyres.2011.12.008_bib0320) 2002; 24 Clemens (10.1016/j.eplepsyres.2011.12.008_bib0090) 2008; 17 Pascual-Marqui (10.1016/j.eplepsyres.2011.12.008_bib0315) 1994; 18 Moeller (10.1016/j.eplepsyres.2011.12.008_bib0285) 2010; 51 Holmes (10.1016/j.eplepsyres.2011.12.008_bib0160) 2010; 49 Lüders (10.1016/j.eplepsyres.2011.12.008_bib0240) 1991 Melø (10.1016/j.eplepsyres.2011.12.008_bib0275) 2006; 26 Rodin (10.1016/j.eplepsyres.2011.12.008_bib0360) 1984 Koepp (10.1016/j.eplepsyres.2011.12.008_bib0460) 2006 Liu (10.1016/j.eplepsyres.2011.12.008_bib0230) 2008; 49 Shackman (10.1016/j.eplepsyres.2011.12.008_bib0380) 2010; 51 McCormick (10.1016/j.eplepsyres.2011.12.008_bib0260) 2001; 63 Holmes (10.1016/j.eplepsyres.2011.12.008_bib0155) 2004; 45 Nunez (10.1016/j.eplepsyres.2011.12.008_bib0295) 1995 Pascual-Marqui (10.1016/j.eplepsyres.2011.12.008_bib0325) 2002; 30 Qiao (10.1016/j.eplepsyres.2011.12.008_bib0340) 1993; 13 Robinson (10.1016/j.eplepsyres.2011.12.008_bib0355) 2004; 23 Lombroso (10.1016/j.eplepsyres.2011.12.008_bib0235) 1997; 38 Brandeis (10.1016/j.eplepsyres.2011.12.008_bib0060) 2009 Sakurai (10.1016/j.eplepsyres.2011.12.008_bib0365) 2010; 89 Amor (10.1016/j.eplepsyres.2011.12.008_bib0015) 2009; 45 Kozelka (10.1016/j.eplepsyres.2011.12.008_bib0210) 1990; 7 Basar (10.1016/j.eplepsyres.2011.12.008_bib0035) 1999; vol. II Savic (10.1016/j.eplepsyres.2011.12.008_bib0370) 1998; 39 Winawer (10.1016/j.eplepsyres.2011.12.008_bib0440) 2003; 61 Anderson (10.1016/j.eplepsyres.2011.12.008_bib0020) 2011 Clemens (10.1016/j.eplepsyres.2011.12.008_bib0085) 2007; 118 de Geus (10.1016/j.eplepsyres.2011.12.008_bib0100) 2010; 2 Koepp (10.1016/j.eplepsyres.2011.12.008_bib0195) 2004; 17 Clemens (10.1016/j.eplepsyres.2011.12.008_bib0075) 2000; 42 Nuwer (10.1016/j.eplepsyres.2011.12.008_bib0300) 1994; 91 Panayiotopoulos (10.1016/j.eplepsyres.2011.12.008_bib0310) 2005 O’Muircheartaigh (10.1016/j.eplepsyres.2011.12.008_bib0305) 2011; 76 Carney (10.1016/j.eplepsyres.2011.12.008_bib0070) 2010; 75 Kobayashi (10.1016/j.eplepsyres.2011.12.008_bib0190) 2009; 50 Kondacs (10.1016/j.eplepsyres.2011.12.008_bib0200) 1999; 110 Durner (10.1016/j.eplepsyres.2011.12.008_bib0105) 2001; 49 Gloor (10.1016/j.eplepsyres.2011.12.008_bib0125) 1982 Nair (10.1016/j.eplepsyres.2011.12.008_bib0290) 2004; 6 van Gelder (10.1016/j.eplepsyres.2011.12.008_bib0425) 1983; 24 Gloor (10.1016/j.eplepsyres.2011.12.008_bib0115) 1977; 4 Aird (10.1016/j.eplepsyres.2011.12.008_bib0010) 1984 Timofeev (10.1016/j.eplepsyres.2011.12.008_bib0415) 2004; 123 Spencer (10.1016/j.eplepsyres.2011.12.008_bib0385) 2002; 43 Clemens (10.1016/j.eplepsyres.2011.12.008_bib0080) 2007; 48 Woermann (10.1016/j.eplepsyres.2011.12.008_bib0445) 1998; 121 Plummer (10.1016/j.eplepsyres.2011.12.008_bib0330) 2008; 49 van Beijsterveldt (10.1016/j.eplepsyres.2011.12.008_bib0420) 1994; 94 Bancaud (10.1016/j.eplepsyres.2011.12.008_bib0030) 1974; 37 Woermann (10.1016/j.eplepsyres.2011.12.008_bib0450) 1999; 122 Meencke (10.1016/j.eplepsyres.2011.12.008_bib0265) 1984; 25 Aarabi (10.1016/j.eplepsyres.2011.12.008_bib0005) 2008; 1188 Laufs (10.1016/j.eplepsyres.2011.12.008_bib0220) 2007; 28 Strug (10.1016/j.eplepsyres.2011.12.008_bib0400) 2009; 17 Lüders (10.1016/j.eplepsyres.2011.12.008_bib0245) 2006; 8 Betting (10.1016/j.eplepsyres.2011.12.008_bib0050) 2006; 32 Meeren (10.1016/j.eplepsyres.2011.12.008_bib0270) 2002; 22 Willoughby (10.1016/j.eplepsyres.2011.12.008_bib0435) 2003; 74 Goh (10.1016/j.eplepsyres.2011.12.008_bib0130) 2007; 104 Vulliemoz (10.1016/j.eplepsyres.2011.12.008_bib0430) 2010 Zietsch (10.1016/j.eplepsyres.2011.12.008_bib0455) 2007; 75 Blumenfeld (10.1016/j.eplepsyres.2011.12.008_bib0055) 2003; 19 Savic (10.1016/j.eplepsyres.2011.12.008_bib0375) 2000; 41 Gotman (10.1016/j.eplepsyres.2011.12.008_bib0135) 2008; 49 Kostopoulos (10.1016/j.eplepsyres.2011.12.008_bib0205) 1986; 92 Lantz (10.1016/j.eplepsyres.2011.12.008_bib0215) 2001; 14 Reutens (10.1016/j.eplepsyres.2011.12.008_bib0350) 1993; 34 Puskás (10.1016/j.eplepsyres.2011.12.008_bib0335) 2010; 91 Markand (10.1016/j.eplepsyres.2011.12.008_bib0255) 1990; 7 Reutens (10.1016/j.eplepsyres.2011.12.008_bib0345) 1992; 339 Gasser (10.1016/j.eplepsyres.2011.12.008_bib0110) 1985; 60 ILAE (Commission on Classification and Terminology) (10.1016/j.eplepsyres.2011.12.008_bib0170) 1989; 30 Kim (10.1016/j.eplepsyres.2011.12.008_bib0180) 2007; 37 Lin (10.1016/j.eplepsyres.2011.12.008_bib0225) 2009; 50 Klimesch (10.1016/j.eplepsyres.2011.12.008_bib0185) 1999; 29 |
References_xml | – volume: 23 start-page: 53 year: 2004 end-page: 72 ident: bib0355 article-title: Estimation of multiscale neurophysiologic parameters by electroencephalographic means publication-title: Hum. Brain Mapp. contributor: fullname: O’ Connor – volume: 8 start-page: S1 year: 2006 end-page: S9 ident: bib0245 article-title: The epileptogenic zone: general principles publication-title: Epileptic. Disord. contributor: fullname: Bingman – volume: 45 start-page: 467 year: 2004 end-page: 478 ident: bib0250 article-title: Genetic architecture of idiopathic generalized epilepsy: clinical genetic analysis of 55 multiplex families publication-title: Epilepsia contributor: fullname: Berkovic – volume: 39 start-page: 1839 year: 2008 end-page: 1849 ident: bib0280 article-title: Changes in activity of striato-thalamo-cortical network precede generalized spike wave discharges publication-title: Neuroimage contributor: fullname: Siniatchkin – volume: 19 start-page: 1556 year: 2003 end-page: 1566 ident: bib0055 article-title: Selective frontal, parietal, and temporal networks in generalized seizures publication-title: Neuroimage contributor: fullname: Zubal – volume: 104 start-page: 8685 year: 2007 end-page: 8690 ident: bib0130 article-title: The human disease network publication-title: Proc. Natl. Acad. Sci. USA contributor: fullname: Barabási – start-page: 51 year: 1991 end-page: 62 ident: bib0240 article-title: Conceptual considerations publication-title: Epilepsy Surgery contributor: fullname: Awad – start-page: 271 year: 2005 end-page: 348 ident: bib0310 article-title: Idiopathic generalized epilepsies publication-title: The Epilepsies. Seizures, Syndromes, and Management contributor: fullname: Panayiotopoulos – year: 2010 ident: bib0430 article-title: Connectivity of the supplementary motor area in juvenile myoclonic epilepsy and frontal lobe epilepsy publication-title: Epilepsia contributor: fullname: Duncan – volume: 38 start-page: 797 year: 1997 end-page: 812 ident: bib0235 article-title: Consistent EEG focalities detected in subjects with primary generalized epilepsies monitored for two decades publication-title: Epilepsia contributor: fullname: Lombroso – volume: 49 start-page: 201 year: 2008 end-page: 218 ident: bib0330 article-title: EEG source localization in focal epilepsy: where are we now? publication-title: Epilepsia contributor: fullname: Cook – volume: 6 start-page: 211 year: 1994 end-page: 219 ident: bib0405 article-title: High resolution quantitative EEG analysis publication-title: Brain Topogr. contributor: fullname: Jimenez – volume: 17 start-page: 224 year: 2008 end-page: 233 ident: bib0090 article-title: Valproate decreases EEG synchronization in a use-dependent manner in idiopathic generalized epilepsy publication-title: Seizure contributor: fullname: Clemens – volume: 71 start-page: 1981 year: 2008 end-page: 1985 ident: bib0095 article-title: Nerve fiber impairment of anterior thalamocortical circuitry in juvenile myoclonic epilepsy publication-title: Neurology contributor: fullname: Knecht – volume: 17 start-page: 467 year: 2004 end-page: 474 ident: bib0195 article-title: Epilepsy publication-title: Curr. Opin. Neurol. contributor: fullname: Duncan – volume: 22 start-page: 1480 year: 2002 end-page: 1495 ident: bib0270 article-title: Cortical focus drives widespread corticothalamic networks during spontaneous absence seizures in rats publication-title: J. Neurosci. contributor: fullname: Lopes da Silva – volume: 2007 start-page: 4937 year: 2007 end-page: 4940 ident: bib0025 article-title: Modeling and detecting deep brain activity with MEG & EEG publication-title: Conf. Proc. IEEE Eng. Med. Biol. Soc. contributor: fullname: Baillet – volume: 21 start-page: 527 year: 2004 end-page: 539 ident: bib0140 article-title: Electrical neuroimaging based on biophysical constraints publication-title: Neuroimage contributor: fullname: Gonzalez Andino – volume: 12 start-page: 137 year: 1979 end-page: 147 ident: bib0040 article-title: Vigilance and evaluation of psychotropic drug effect on EEG publication-title: Pharmacopsychiatry contributor: fullname: Bente – volume: 14 start-page: 139 year: 2001 end-page: 147 ident: bib0215 article-title: Noninvasive localization of electromagnetic epileptic activity. II. Demonstration of sublobar accuracy in patients with simultaneous surface and depth recordings publication-title: Brain Topogr. contributor: fullname: Michel – volume: 37 start-page: 275 year: 1974 end-page: 282 ident: bib0030 article-title: “Generalized” epileptic seizures elicited by electrical stimulation of the frontal lobe is man publication-title: Electroencephalogr. Clin. Neurophysiol. contributor: fullname: Buser – volume: 75 start-page: 154 year: 2007 end-page: 164 ident: bib0455 article-title: Common and specific genetic influences on EEG power bands delta, theta, alpha, and beta publication-title: Biol. Psychol. contributor: fullname: Wright – volume: 26 start-page: 1496 year: 2006 end-page: 1506 ident: bib0275 article-title: Cortical glutamate metabolism is enhanced in a genetic model of absence epilepsy publication-title: J. Cereb. Blood Flow Metab. contributor: fullname: Nehlig – volume: 49 start-page: 2078 year: 2008 end-page: 2086 ident: bib0230 article-title: EEG-fMRI study of the ictal and interictal epileptic activity in patients with eyelid myoclonia with absences publication-title: Epilepsia contributor: fullname: Zhou – volume: 75 start-page: 904 year: 2010 end-page: 911 ident: bib0070 article-title: The core network in absence epilepsy. Differences in cortical and thalamic BOLD response publication-title: Neurology contributor: fullname: Jackson – volume: 13 start-page: 4622 year: 1993 end-page: 4635 ident: bib0340 article-title: Developmental analysis of hippocampal mossy fiber outgrowth in a mutant mouse with inherited spike–wave seizures publication-title: J. Neurosci. contributor: fullname: Noebels – volume: 50 start-page: 2549 year: 2009 end-page: 2556 ident: bib0190 article-title: Structures involved at the time of temporal lobe spikes revealed by inter-individual group analysis of EEG/fMRI data publication-title: Epilepsia contributor: fullname: Gotman – volume: vol. II start-page: 393 year: 1999 end-page: 406 ident: bib0035 article-title: Brain functioning: integrative models publication-title: Brain Function and Oscillations contributor: fullname: Schürmann – volume: 49 start-page: 328 year: 2001 end-page: 335 ident: bib0105 article-title: Genome scan of idiopathic generalized epilepsy: evidence for major susceptibility gene and modification genes influencing the seizure type publication-title: Ann. Neurol. contributor: fullname: Greenberg – volume: 7 start-page: 191 year: 1990 end-page: 207 ident: bib0210 article-title: Beta and mu rhythms publication-title: J. Clin. Neurophysiol. contributor: fullname: Pedley – volume: 24 start-page: 91 year: 2002 end-page: 96 ident: bib0320 article-title: Functional imaging with low-resolution brain electromagnetic tomography (LORETA): a review publication-title: Methods Find. Exp. Clin. Pharmacol. contributor: fullname: Pascual-Marqui – volume: 86 start-page: 1 year: 2001 end-page: 39 ident: bib0395 article-title: Impact of network activities on neuronal properties in corticothalamic systems publication-title: Am. Physiol. Soc. contributor: fullname: Steriade – volume: 20 start-page: 571 year: 1979 end-page: 588 ident: bib0120 article-title: Generalized epilepsy with spike and wave discharge: a reinterpretation of its electrographic and clinical manifestations publication-title: Epilepsia contributor: fullname: Gloor – volume: 37 start-page: 1132 year: 2007 end-page: 1137 ident: bib0180 article-title: Regional grey matter abnormalities in juvenile myoclonic epilepsy: a voxel-based morphometry study publication-title: Neuroimage contributor: fullname: Kang – volume: 7 start-page: 163 year: 1990 end-page: 189 ident: bib0255 article-title: Alpha rhythms publication-title: J. Clin. Neurophysiol. contributor: fullname: Markand – start-page: 45 year: 1982 end-page: 56 ident: bib0125 article-title: Neurophysiological genetic and biochemical nature of the epileptic diathesis publication-title: Henry Gastaut and the Marseilles School's Contribution to the Neurosciences contributor: fullname: van Gelder – volume: 43 start-page: 219 year: 2002 end-page: 227 ident: bib0385 article-title: Neural networks in human epilepsy: evidence of and implications for treatment publication-title: Epilepsia contributor: fullname: Spencer – volume: 76 start-page: 34 year: 2011 end-page: 40 ident: bib0305 article-title: Focal structural changes and cognitive dysfunction in juvenile myoclonic epilepsy publication-title: Neurology contributor: fullname: Richardson – year: 1984 ident: bib0010 article-title: The Epilepsies. A Critical Review contributor: fullname: Woodbury – volume: 25 start-page: 8 year: 1984 end-page: 21 ident: bib0265 article-title: Neuropathological findings in primary generalized epilepsies: a study of eight cases publication-title: Epilepsia contributor: fullname: Janz – start-page: 1 year: 2009 end-page: 24 ident: bib0060 article-title: From neuronal activity to scalp potential fields publication-title: Electrical Neuroimaging contributor: fullname: Amzica – volume: 28 start-page: 193 year: 1997 end-page: 206 ident: bib0165 article-title: Long-term studies on patients with absence and bilateral spike–wave complexes: 430 patients, up to 52 years follow-up publication-title: Clin. Electroencephalogr. contributor: fullname: Kaydanova – volume: 91 start-page: 94 year: 2010 end-page: 100 ident: bib0335 article-title: Quantitative EEG abnormalities in persons with “pure” epileptic predisposition without epilepsy: a low resolution electromagnetic tomography (LORETA) study publication-title: Epilepsy Res. contributor: fullname: Clemens – volume: 30 start-page: 389 year: 1989 end-page: 399 ident: bib0170 article-title: Proposal for revised classification of epilepsies and epileptic syndromes publication-title: Epilepsia contributor: fullname: ILAE (Commission on Classification and Terminology) – year: 2011 ident: bib0020 article-title: Understanding juvenile myoclonic epilepsy: contributions from neuroimaging publication-title: Epilepsy Res. contributor: fullname: Hamandi – volume: 1188 start-page: 207 year: 2008 end-page: 221 ident: bib0005 article-title: Does spatiotemporal synchronization of EEG change prior to absence seizures? publication-title: Brain Res. contributor: fullname: Grebe – volume: 43 start-page: 435 year: 1998 end-page: 445 ident: bib0045 article-title: Epilepsies in twins: genetics of the major epilepsy syndromes publication-title: Ann. Neurol. contributor: fullname: Hopper – volume: 51 start-page: 1319 year: 2010 end-page: 1333 ident: bib0380 article-title: Identifying robust and sensitive frequency bands for interrogating neural oscillations publication-title: Neuroimage contributor: fullname: Davidson – volume: 2 start-page: 63 year: 2010 ident: bib0100 article-title: From genotype to EEG endophenotype: a route for post-genomic understanding of complex psychiatric disease? publication-title: Genome Med. contributor: fullname: de Geus – volume: 50 start-page: 1191 year: 2009 end-page: 1200 ident: bib0225 article-title: Magnetic resonance spectroscopy reveals an epileptic network in juvenile myoclonic epilepsy publication-title: Epilepsia contributor: fullname: Yacubian – volume: 29 start-page: 169 year: 1999 end-page: 195 ident: bib0185 article-title: EEG alpha and theta oscillations reflect cognitive and memory performance: a review and analysis publication-title: Brain Res. Brain Res. Rev. contributor: fullname: Klimesch – start-page: 163 year: 2006 end-page: 182 ident: bib0460 article-title: Systems and networks in myoclonic seizures and epilepsies publication-title: Generalized seizures: from clinical phenomenology to underlying systems and networks. Progress in Epileptic Disorders contributor: fullname: Hamandi – volume: 63 start-page: 815 year: 2001 end-page: 846 ident: bib0260 article-title: On the cellular and network bases of epileptic seizures publication-title: Annu. Rev. Physiol. contributor: fullname: Contreras – volume: 18 start-page: 49 year: 1994 end-page: 65 ident: bib0315 article-title: Low resolution electromagnetic tomography. A new method for localizing electrical activity in the brain publication-title: Int. J. Psychophysiol. contributor: fullname: Lehmann – volume: 41 start-page: 290 year: 2000 end-page: 296 ident: bib0375 article-title: MR spectroscopy shows reduced frontal lobe concentrations of N-acetylaspartate in patients with juvenile myoclonic epilepsy publication-title: Epilepsia contributor: fullname: Helms – volume: 91 start-page: 1 year: 1994 end-page: 5 ident: bib0300 article-title: IFCN guidelines for topographic and frequency analysis of EEGs and EPs. Report of an IFCN committee publication-title: Electroencephalogr. Clin. Neurophysiol. contributor: fullname: Vibert – volume: 51 start-page: 2000 year: 2010 end-page: 2010 ident: bib0285 article-title: Absence seizures: individual patterns revealed by EEG-fMRI publication-title: Epilepsia contributor: fullname: Gotman – volume: 110 start-page: 1708 year: 1999 end-page: 1716 ident: bib0200 article-title: Long-term intra-individual variability of the background EEG in normals publication-title: Clin. Neurophysiol. contributor: fullname: Szabo – volume: 34 start-page: 351 year: 1993 end-page: 355 ident: bib0350 article-title: Magnetic stimulation of the brain in generalised epilepsy: reversal of cortical hyperexcitability by anticonvulsants publication-title: Ann. Neurol. contributor: fullname: Bladin – volume: 45 start-page: 1568 year: 2004 end-page: 1579 ident: bib0155 article-title: Are “generalized” seizures truly generalized? Evidence of localized mesial frontal and frontopolar discharges in absence publication-title: Epilepsia contributor: fullname: Tucker – volume: 28 start-page: 1023 year: 2007 end-page: 1032 ident: bib0220 article-title: Temporal lobe interictal epileptic discharges affect cerebral activity in “default mode” brain regions publication-title: Hum. Brain Mapp. contributor: fullname: Lemieux – start-page: 293 year: 1984 end-page: 301 ident: bib0360 article-title: Sleep deprivation and epileptological implications publication-title: Epilepsy, Sleep and Sleep Deprivation contributor: fullname: Rodin – volume: 17 start-page: 1171 year: 2009 end-page: 1181 ident: bib0400 article-title: Centrotemporal sharp wave EEG trait in rolandic epilepsy maps to Elongator Protein Complex 4 (ELP4) publication-title: Eur. J. Hum. Genet. contributor: fullname: Pal – volume: 50 start-page: 2466 year: 2009 end-page: 2472 ident: bib0065 article-title: Frontal and temporal volumes in Childhood Absence Epilepsy publication-title: Epilepsia contributor: fullname: Shields – volume: 123 start-page: 299 year: 2004 end-page: 336 ident: bib0415 article-title: Neocortical seizures: initiation, development and cessation publication-title: Neuroscience contributor: fullname: Steriade – volume: 94 start-page: 319 year: 1994 end-page: 330 ident: bib0420 article-title: Genetics of the human electroencephalogram (EEG) and event-related brain potentials (ERPs): a review publication-title: Hum. Genet. contributor: fullname: Boomsma – volume: 122 start-page: 2101 year: 1999 end-page: 2108 ident: bib0450 article-title: Abnormal cerebral structure in juvenile myoclonic epilepsy demonstrated with voxel-based analysis of MRI publication-title: Brain contributor: fullname: Duncan – volume: 39 start-page: 364 year: 1998 end-page: 370 ident: bib0370 article-title: Brain distortions in patients with primarily generalized tonic–clonic seizures publication-title: Epilepsia contributor: fullname: Pauli – volume: 60 start-page: 312 year: 1985 end-page: 319 ident: bib0110 article-title: Test–retest reliability of spectral parameters of the EEG publication-title: Electroencephalogr. Clin. Neurophysiol. contributor: fullname: Steinberg – volume: 255 start-page: 561 year: 2008 end-page: 566 ident: bib0410 article-title: Cortical thickness abnormality in juvenile myoclonic epilepsy publication-title: J. Neurol. contributor: fullname: Hong – volume: 42 start-page: 105 year: 2000 end-page: 115 ident: bib0075 article-title: EEG frequency profiles of idiopathic generalized epilepsy syndromes publication-title: Epilepsy Res. contributor: fullname: Barta – volume: 6 start-page: 77 year: 2004 end-page: 83 ident: bib0290 article-title: A critical review of the different conceptual hypotheses framing human focal epilepsy publication-title: Epileptic. Disord. contributor: fullname: Lüders – volume: 89 start-page: 176 year: 2010 end-page: 184 ident: bib0365 article-title: Generalized spike–wave discharges involve a default mode network in patients with juvenile absence epilepsy: a MEG study publication-title: Epilepsy Res. contributor: fullname: Koyama – volume: 74 start-page: 51 year: 2003 end-page: 55 ident: bib0435 article-title: Persistent abnormality detected in the non-ictal electroencephalogram in primary generalized epilepsy publication-title: J. Neurol. Neurosurg. Psychiatry contributor: fullname: Wilcox – volume: 150 start-page: 143 year: 2005 end-page: 171 ident: bib0175 article-title: From synchronous neuronal discharges to subjective awareness? publication-title: Prog. Brain Res. contributor: fullname: John – volume: 24 start-page: 200 year: 1983 end-page: 213 ident: bib0425 article-title: Feline generalised penicillin epilepsy: changes of glutamine acid and taurin parallel to the progressive increase in excitability of the cortex publication-title: Epilepsia contributor: fullname: Gloor – volume: 39 start-page: 755 year: 2008 end-page: 774 ident: bib0150 article-title: Concordance between distributed EEG source localization and simultaneous EEG-fMRI studies of epileptic spikes publication-title: Neuroimage contributor: fullname: Gotman – start-page: 1 year: 1995 end-page: 18 ident: bib0295 article-title: Quantitative states of neocortex publication-title: Neocortical Dynamics and Human EEG Rhythms contributor: fullname: Nunez – volume: 85 start-page: 187 year: 2009 end-page: 198 ident: bib0390 article-title: Network characteristics of idiopathic generalized epilepsies in combined MEG/EEG publication-title: Epilepsy Res. contributor: fullname: Rampp – volume: 61 start-page: 1576 year: 2003 end-page: 1581 ident: bib0440 article-title: Genetic influences on myoclonic and absence seizures publication-title: Neurology contributor: fullname: Ottman – volume: 49 start-page: 42 year: 2008 end-page: 51 ident: bib0135 article-title: Epileptic networks studied with EEG-fMRI publication-title: Epilepsia contributor: fullname: Gotman – volume: 121 start-page: 1661 year: 1998 end-page: 1667 ident: bib0445 article-title: Quantitative MRI in patients with idiopathic generalized epilepsy. Evidence of widespread cerebral structural changes publication-title: Brain contributor: fullname: Duncan – volume: 4 start-page: 326 year: 1977 end-page: 333 ident: bib0115 article-title: Brain lesions that produce delta waves in the EEG publication-title: Neurology contributor: fullname: Schaul – volume: 76 start-page: 139 year: 2005 end-page: 146 ident: bib0145 article-title: Malic enzyme 2 may underlie susceptibility to adolescent-onset idiopathic generalized epilepsy publication-title: Am. J. Hum. Genet. contributor: fullname: Kang – volume: 49 start-page: 80 year: 2010 end-page: 93 ident: bib0160 article-title: Evidence that juvenile myoclonic epilepsy is a disorder of frontotemporal corticothalamic networks publication-title: Neuroimage contributor: fullname: Tucker – volume: 92 start-page: 20 year: 1986 end-page: 36 ident: bib0205 article-title: Neuronal sensitivity to GABA and glutamate in generalised epilepsy with spike and wave discharges publication-title: Exp. Neurol. contributor: fullname: Kostopoulos – volume: 48 start-page: 941 year: 2007 end-page: 949 ident: bib0080 article-title: Characteristic distribution of interictal brain electrical activity in idiopathic generalized epilepsy publication-title: Epilepsia contributor: fullname: Kondákor – volume: 339 start-page: 362 year: 1992 end-page: 363 ident: bib0345 article-title: Increased cortical excitability in generalised epilepsy demonstrated with transcranial magnetic stimulation publication-title: Lancet contributor: fullname: Berkovic – volume: 32 start-page: 498 year: 2006 end-page: 502 ident: bib0050 article-title: Voxel-based morphometry in patients with idiopathic generalized epilepsies publication-title: Neuroimage contributor: fullname: Cendes – volume: 45 start-page: 950 year: 2009 end-page: 962 ident: bib0015 article-title: Cortical local and long-range synchronization interplay in human absence seizure initiation publication-title: Neuroimage contributor: fullname: Quyen – volume: 118 start-page: 910 year: 2007 end-page: 917 ident: bib0085 article-title: Lamotrigine decreases EEG synchronization in a use-dependent manner in patients with idiopathic generalized epilepsy publication-title: Clin. Neurophysiol. contributor: fullname: Hollódy – volume: 30 start-page: 81 year: 2002 end-page: 94 ident: bib0325 article-title: Functional imaging with low-resolution brain electromagnetic tomography (LORETA): review, new comparisons, and new validation publication-title: Jpn. J. Clin. Neurophysiol. contributor: fullname: Lehmann – volume: 45 start-page: 950 year: 2009 ident: 10.1016/j.eplepsyres.2011.12.008_bib0015 article-title: Cortical local and long-range synchronization interplay in human absence seizure initiation publication-title: Neuroimage doi: 10.1016/j.neuroimage.2008.12.011 contributor: fullname: Amor – volume: 37 start-page: 1132 year: 2007 ident: 10.1016/j.eplepsyres.2011.12.008_bib0180 article-title: Regional grey matter abnormalities in juvenile myoclonic epilepsy: a voxel-based morphometry study publication-title: Neuroimage doi: 10.1016/j.neuroimage.2007.06.025 contributor: fullname: Kim – volume: 39 start-page: 755 year: 2008 ident: 10.1016/j.eplepsyres.2011.12.008_bib0150 article-title: Concordance between distributed EEG source localization and simultaneous EEG-fMRI studies of epileptic spikes publication-title: Neuroimage doi: 10.1016/j.neuroimage.2007.08.020 contributor: fullname: Grova – volume: 121 start-page: 1661 year: 1998 ident: 10.1016/j.eplepsyres.2011.12.008_bib0445 article-title: Quantitative MRI in patients with idiopathic generalized epilepsy. Evidence of widespread cerebral structural changes publication-title: Brain doi: 10.1093/brain/121.9.1661 contributor: fullname: Woermann – volume: 45 start-page: 1568 year: 2004 ident: 10.1016/j.eplepsyres.2011.12.008_bib0155 article-title: Are “generalized” seizures truly generalized? Evidence of localized mesial frontal and frontopolar discharges in absence publication-title: Epilepsia doi: 10.1111/j.0013-9580.2004.23204.x contributor: fullname: Holmes – volume: 19 start-page: 1556 year: 2003 ident: 10.1016/j.eplepsyres.2011.12.008_bib0055 article-title: Selective frontal, parietal, and temporal networks in generalized seizures publication-title: Neuroimage doi: 10.1016/S1053-8119(03)00204-0 contributor: fullname: Blumenfeld – volume: 39 start-page: 364 year: 1998 ident: 10.1016/j.eplepsyres.2011.12.008_bib0370 article-title: Brain distortions in patients with primarily generalized tonic–clonic seizures publication-title: Epilepsia doi: 10.1111/j.1528-1157.1998.tb01388.x contributor: fullname: Savic – volume: 2 start-page: 63 year: 2010 ident: 10.1016/j.eplepsyres.2011.12.008_bib0100 article-title: From genotype to EEG endophenotype: a route for post-genomic understanding of complex psychiatric disease? publication-title: Genome Med. doi: 10.1186/gm184 contributor: fullname: de Geus – volume: 123 start-page: 299 year: 2004 ident: 10.1016/j.eplepsyres.2011.12.008_bib0415 article-title: Neocortical seizures: initiation, development and cessation publication-title: Neuroscience doi: 10.1016/j.neuroscience.2003.08.051 contributor: fullname: Timofeev – volume: 14 start-page: 139 year: 2001 ident: 10.1016/j.eplepsyres.2011.12.008_bib0215 article-title: Noninvasive localization of electromagnetic epileptic activity. II. Demonstration of sublobar accuracy in patients with simultaneous surface and depth recordings publication-title: Brain Topogr. doi: 10.1023/A:1012996930489 contributor: fullname: Lantz – volume: 110 start-page: 1708 year: 1999 ident: 10.1016/j.eplepsyres.2011.12.008_bib0200 article-title: Long-term intra-individual variability of the background EEG in normals publication-title: Clin. Neurophysiol. doi: 10.1016/S1388-2457(99)00122-4 contributor: fullname: Kondacs – volume: 17 start-page: 467 year: 2004 ident: 10.1016/j.eplepsyres.2011.12.008_bib0195 article-title: Epilepsy publication-title: Curr. Opin. Neurol. doi: 10.1097/01.wco.0000137539.91738.2b contributor: fullname: Koepp – volume: 22 start-page: 1480 year: 2002 ident: 10.1016/j.eplepsyres.2011.12.008_bib0270 article-title: Cortical focus drives widespread corticothalamic networks during spontaneous absence seizures in rats publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.22-04-01480.2002 contributor: fullname: Meeren – volume: 86 start-page: 1 year: 2001 ident: 10.1016/j.eplepsyres.2011.12.008_bib0395 article-title: Impact of network activities on neuronal properties in corticothalamic systems publication-title: Am. Physiol. Soc. contributor: fullname: Steriade – volume: 339 start-page: 362 year: 1992 ident: 10.1016/j.eplepsyres.2011.12.008_bib0345 article-title: Increased cortical excitability in generalised epilepsy demonstrated with transcranial magnetic stimulation publication-title: Lancet doi: 10.1016/0140-6736(92)91679-3 contributor: fullname: Reutens – start-page: 271 year: 2005 ident: 10.1016/j.eplepsyres.2011.12.008_bib0310 article-title: Idiopathic generalized epilepsies contributor: fullname: Panayiotopoulos – start-page: 1 year: 2009 ident: 10.1016/j.eplepsyres.2011.12.008_bib0060 article-title: From neuronal activity to scalp potential fields contributor: fullname: Brandeis – volume: 51 start-page: 1319 year: 2010 ident: 10.1016/j.eplepsyres.2011.12.008_bib0380 article-title: Identifying robust and sensitive frequency bands for interrogating neural oscillations publication-title: Neuroimage doi: 10.1016/j.neuroimage.2010.03.037 contributor: fullname: Shackman – volume: 20 start-page: 571 year: 1979 ident: 10.1016/j.eplepsyres.2011.12.008_bib0120 article-title: Generalized epilepsy with spike and wave discharge: a reinterpretation of its electrographic and clinical manifestations publication-title: Epilepsia doi: 10.1111/j.1528-1157.1979.tb04840.x contributor: fullname: Gloor – volume: 6 start-page: 77 year: 2004 ident: 10.1016/j.eplepsyres.2011.12.008_bib0290 article-title: A critical review of the different conceptual hypotheses framing human focal epilepsy publication-title: Epileptic. Disord. doi: 10.1684/j.1950-6945.2004.tb00054.x contributor: fullname: Nair – start-page: 1 year: 1995 ident: 10.1016/j.eplepsyres.2011.12.008_bib0295 article-title: Quantitative states of neocortex contributor: fullname: Nunez – year: 2011 ident: 10.1016/j.eplepsyres.2011.12.008_bib0020 article-title: Understanding juvenile myoclonic epilepsy: contributions from neuroimaging publication-title: Epilepsy Res. doi: 10.1016/j.eplepsyres.2011.03.008 contributor: fullname: Anderson – volume: 43 start-page: 219 year: 2002 ident: 10.1016/j.eplepsyres.2011.12.008_bib0385 article-title: Neural networks in human epilepsy: evidence of and implications for treatment publication-title: Epilepsia doi: 10.1046/j.1528-1157.2002.26901.x contributor: fullname: Spencer – volume: 7 start-page: 163 year: 1990 ident: 10.1016/j.eplepsyres.2011.12.008_bib0255 article-title: Alpha rhythms publication-title: J. Clin. Neurophysiol. doi: 10.1097/00004691-199004000-00003 contributor: fullname: Markand – volume: 91 start-page: 94 year: 2010 ident: 10.1016/j.eplepsyres.2011.12.008_bib0335 article-title: Quantitative EEG abnormalities in persons with “pure” epileptic predisposition without epilepsy: a low resolution electromagnetic tomography (LORETA) study publication-title: Epilepsy Res. doi: 10.1016/j.eplepsyres.2010.07.001 contributor: fullname: Puskás – volume: 49 start-page: 328 year: 2001 ident: 10.1016/j.eplepsyres.2011.12.008_bib0105 article-title: Genome scan of idiopathic generalized epilepsy: evidence for major susceptibility gene and modification genes influencing the seizure type publication-title: Ann. Neurol. doi: 10.1002/ana.69 contributor: fullname: Durner – volume: 49 start-page: 201 year: 2008 ident: 10.1016/j.eplepsyres.2011.12.008_bib0330 article-title: EEG source localization in focal epilepsy: where are we now? publication-title: Epilepsia doi: 10.1111/j.1528-1167.2007.01381.x contributor: fullname: Plummer – volume: 24 start-page: 200 year: 1983 ident: 10.1016/j.eplepsyres.2011.12.008_bib0425 article-title: Feline generalised penicillin epilepsy: changes of glutamine acid and taurin parallel to the progressive increase in excitability of the cortex publication-title: Epilepsia doi: 10.1111/j.1528-1157.1983.tb04880.x contributor: fullname: van Gelder – volume: 71 start-page: 1981 year: 2008 ident: 10.1016/j.eplepsyres.2011.12.008_bib0095 article-title: Nerve fiber impairment of anterior thalamocortical circuitry in juvenile myoclonic epilepsy publication-title: Neurology doi: 10.1212/01.wnl.0000336969.98241.17 contributor: fullname: Deppe – volume: 2007 start-page: 4937 year: 2007 ident: 10.1016/j.eplepsyres.2011.12.008_bib0025 article-title: Modeling and detecting deep brain activity with MEG & EEG publication-title: Conf. Proc. IEEE Eng. Med. Biol. Soc. contributor: fullname: Attal – volume: 255 start-page: 561 year: 2008 ident: 10.1016/j.eplepsyres.2011.12.008_bib0410 article-title: Cortical thickness abnormality in juvenile myoclonic epilepsy publication-title: J. Neurol. doi: 10.1007/s00415-008-0745-6 contributor: fullname: Tae – volume: 37 start-page: 275 year: 1974 ident: 10.1016/j.eplepsyres.2011.12.008_bib0030 article-title: “Generalized” epileptic seizures elicited by electrical stimulation of the frontal lobe is man publication-title: Electroencephalogr. Clin. Neurophysiol. doi: 10.1016/0013-4694(74)90031-5 contributor: fullname: Bancaud – volume: 49 start-page: 80 year: 2010 ident: 10.1016/j.eplepsyres.2011.12.008_bib0160 article-title: Evidence that juvenile myoclonic epilepsy is a disorder of frontotemporal corticothalamic networks publication-title: Neuroimage doi: 10.1016/j.neuroimage.2009.08.004 contributor: fullname: Holmes – start-page: 163 year: 2006 ident: 10.1016/j.eplepsyres.2011.12.008_bib0460 article-title: Systems and networks in myoclonic seizures and epilepsies contributor: fullname: Koepp – volume: 89 start-page: 176 year: 2010 ident: 10.1016/j.eplepsyres.2011.12.008_bib0365 article-title: Generalized spike–wave discharges involve a default mode network in patients with juvenile absence epilepsy: a MEG study publication-title: Epilepsy Res. doi: 10.1016/j.eplepsyres.2009.12.004 contributor: fullname: Sakurai – volume: 18 start-page: 49 year: 1994 ident: 10.1016/j.eplepsyres.2011.12.008_bib0315 article-title: Low resolution electromagnetic tomography. A new method for localizing electrical activity in the brain publication-title: Int. J. Psychophysiol. doi: 10.1016/0167-8760(84)90014-X contributor: fullname: Pascual-Marqui – volume: 12 start-page: 137 year: 1979 ident: 10.1016/j.eplepsyres.2011.12.008_bib0040 article-title: Vigilance and evaluation of psychotropic drug effect on EEG publication-title: Pharmacopsychiatry doi: 10.1055/s-0028-1094604 contributor: fullname: Bente – volume: 85 start-page: 187 year: 2009 ident: 10.1016/j.eplepsyres.2011.12.008_bib0390 article-title: Network characteristics of idiopathic generalized epilepsies in combined MEG/EEG publication-title: Epilepsy Res. doi: 10.1016/j.eplepsyres.2009.03.015 contributor: fullname: Stefan – volume: 50 start-page: 2466 year: 2009 ident: 10.1016/j.eplepsyres.2011.12.008_bib0065 article-title: Frontal and temporal volumes in Childhood Absence Epilepsy publication-title: Epilepsia doi: 10.1111/j.1528-1167.2009.02198.x contributor: fullname: Caplan – volume: 17 start-page: 224 year: 2008 ident: 10.1016/j.eplepsyres.2011.12.008_bib0090 article-title: Valproate decreases EEG synchronization in a use-dependent manner in idiopathic generalized epilepsy publication-title: Seizure doi: 10.1016/j.seizure.2007.07.005 contributor: fullname: Clemens – volume: 91 start-page: 1 year: 1994 ident: 10.1016/j.eplepsyres.2011.12.008_bib0300 article-title: IFCN guidelines for topographic and frequency analysis of EEGs and EPs. Report of an IFCN committee publication-title: Electroencephalogr. Clin. Neurophysiol. doi: 10.1016/0013-4694(94)90011-6 contributor: fullname: Nuwer – volume: 8 start-page: S1 year: 2006 ident: 10.1016/j.eplepsyres.2011.12.008_bib0245 article-title: The epileptogenic zone: general principles publication-title: Epileptic. Disord. doi: 10.1684/j.1950-6945.2006.tb00204.x contributor: fullname: Lüders – volume: 4 start-page: 326 year: 1977 ident: 10.1016/j.eplepsyres.2011.12.008_bib0115 article-title: Brain lesions that produce delta waves in the EEG publication-title: Neurology doi: 10.1212/WNL.27.4.326 contributor: fullname: Gloor – volume: 17 start-page: 1171 year: 2009 ident: 10.1016/j.eplepsyres.2011.12.008_bib0400 article-title: Centrotemporal sharp wave EEG trait in rolandic epilepsy maps to Elongator Protein Complex 4 (ELP4) publication-title: Eur. J. Hum. Genet. doi: 10.1038/ejhg.2008.267 contributor: fullname: Strug – volume: 76 start-page: 139 year: 2005 ident: 10.1016/j.eplepsyres.2011.12.008_bib0145 article-title: Malic enzyme 2 may underlie susceptibility to adolescent-onset idiopathic generalized epilepsy publication-title: Am. J. Hum. Genet. doi: 10.1086/426735 contributor: fullname: Greenberg – volume: 30 start-page: 389 year: 1989 ident: 10.1016/j.eplepsyres.2011.12.008_bib0170 article-title: Proposal for revised classification of epilepsies and epileptic syndromes publication-title: Epilepsia doi: 10.1111/j.1528-1157.1989.tb05316.x contributor: fullname: ILAE (Commission on Classification and Terminology) – volume: 61 start-page: 1576 year: 2003 ident: 10.1016/j.eplepsyres.2011.12.008_bib0440 article-title: Genetic influences on myoclonic and absence seizures publication-title: Neurology doi: 10.1212/WNL.61.11.1576 contributor: fullname: Winawer – volume: 30 start-page: 81 year: 2002 ident: 10.1016/j.eplepsyres.2011.12.008_bib0325 article-title: Functional imaging with low-resolution brain electromagnetic tomography (LORETA): review, new comparisons, and new validation publication-title: Jpn. J. Clin. Neurophysiol. contributor: fullname: Pascual-Marqui – volume: 13 start-page: 4622 year: 1993 ident: 10.1016/j.eplepsyres.2011.12.008_bib0340 article-title: Developmental analysis of hippocampal mossy fiber outgrowth in a mutant mouse with inherited spike–wave seizures publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.13-11-04622.1993 contributor: fullname: Qiao – volume: 74 start-page: 51 year: 2003 ident: 10.1016/j.eplepsyres.2011.12.008_bib0435 article-title: Persistent abnormality detected in the non-ictal electroencephalogram in primary generalized epilepsy publication-title: J. Neurol. Neurosurg. Psychiatry doi: 10.1136/jnnp.74.1.51 contributor: fullname: Willoughby – volume: 25 start-page: 8 year: 1984 ident: 10.1016/j.eplepsyres.2011.12.008_bib0265 article-title: Neuropathological findings in primary generalized epilepsies: a study of eight cases publication-title: Epilepsia doi: 10.1111/j.1528-1157.1984.tb04149.x contributor: fullname: Meencke – volume: 26 start-page: 1496 year: 2006 ident: 10.1016/j.eplepsyres.2011.12.008_bib0275 article-title: Cortical glutamate metabolism is enhanced in a genetic model of absence epilepsy publication-title: J. Cereb. Blood Flow Metab. doi: 10.1038/sj.jcbfm.9600300 contributor: fullname: Melø – volume: 49 start-page: 42 issue: Suppl. 3 year: 2008 ident: 10.1016/j.eplepsyres.2011.12.008_bib0135 article-title: Epileptic networks studied with EEG-fMRI publication-title: Epilepsia doi: 10.1111/j.1528-1167.2008.01509.x contributor: fullname: Gotman – volume: 42 start-page: 105 year: 2000 ident: 10.1016/j.eplepsyres.2011.12.008_bib0075 article-title: EEG frequency profiles of idiopathic generalized epilepsy syndromes publication-title: Epilepsy Res. doi: 10.1016/S0920-1211(00)00167-4 contributor: fullname: Clemens – volume: 104 start-page: 8685 year: 2007 ident: 10.1016/j.eplepsyres.2011.12.008_bib0130 article-title: The human disease network publication-title: Proc. Natl. Acad. Sci. USA doi: 10.1073/pnas.0701361104 contributor: fullname: Goh – volume: 24 start-page: 91 year: 2002 ident: 10.1016/j.eplepsyres.2011.12.008_bib0320 article-title: Functional imaging with low-resolution brain electromagnetic tomography (LORETA): a review publication-title: Methods Find. Exp. Clin. Pharmacol. contributor: fullname: Pascual-Marqui – volume: 21 start-page: 527 year: 2004 ident: 10.1016/j.eplepsyres.2011.12.008_bib0140 article-title: Electrical neuroimaging based on biophysical constraints publication-title: Neuroimage doi: 10.1016/j.neuroimage.2003.09.051 contributor: fullname: Grave de Peralta Menendez – volume: 49 start-page: 2078 year: 2008 ident: 10.1016/j.eplepsyres.2011.12.008_bib0230 article-title: EEG-fMRI study of the ictal and interictal epileptic activity in patients with eyelid myoclonia with absences publication-title: Epilepsia doi: 10.1111/j.1528-1167.2008.01724.x contributor: fullname: Liu – volume: 51 start-page: 2000 year: 2010 ident: 10.1016/j.eplepsyres.2011.12.008_bib0285 article-title: Absence seizures: individual patterns revealed by EEG-fMRI publication-title: Epilepsia doi: 10.1111/j.1528-1167.2010.02698.x contributor: fullname: Moeller – year: 1984 ident: 10.1016/j.eplepsyres.2011.12.008_bib0010 contributor: fullname: Aird – volume: 6 start-page: 211 year: 1994 ident: 10.1016/j.eplepsyres.2011.12.008_bib0405 article-title: High resolution quantitative EEG analysis publication-title: Brain Topogr. doi: 10.1007/BF01187711 contributor: fullname: Szava – volume: vol. II start-page: 393 year: 1999 ident: 10.1016/j.eplepsyres.2011.12.008_bib0035 article-title: Brain functioning: integrative models contributor: fullname: Basar – volume: 41 start-page: 290 year: 2000 ident: 10.1016/j.eplepsyres.2011.12.008_bib0375 article-title: MR spectroscopy shows reduced frontal lobe concentrations of N-acetylaspartate in patients with juvenile myoclonic epilepsy publication-title: Epilepsia doi: 10.1111/j.1528-1157.2000.tb00158.x contributor: fullname: Savic – volume: 43 start-page: 435 year: 1998 ident: 10.1016/j.eplepsyres.2011.12.008_bib0045 article-title: Epilepsies in twins: genetics of the major epilepsy syndromes publication-title: Ann. Neurol. doi: 10.1002/ana.410430405 contributor: fullname: Berkovic – volume: 76 start-page: 34 year: 2011 ident: 10.1016/j.eplepsyres.2011.12.008_bib0305 article-title: Focal structural changes and cognitive dysfunction in juvenile myoclonic epilepsy publication-title: Neurology doi: 10.1212/WNL.0b013e318203e93d contributor: fullname: O’Muircheartaigh – volume: 32 start-page: 498 year: 2006 ident: 10.1016/j.eplepsyres.2011.12.008_bib0050 article-title: Voxel-based morphometry in patients with idiopathic generalized epilepsies publication-title: Neuroimage doi: 10.1016/j.neuroimage.2006.04.174 contributor: fullname: Betting – volume: 75 start-page: 904 year: 2010 ident: 10.1016/j.eplepsyres.2011.12.008_bib0070 article-title: The core network in absence epilepsy. Differences in cortical and thalamic BOLD response publication-title: Neurology doi: 10.1212/WNL.0b013e3181f11c06 contributor: fullname: Carney – volume: 34 start-page: 351 year: 1993 ident: 10.1016/j.eplepsyres.2011.12.008_bib0350 article-title: Magnetic stimulation of the brain in generalised epilepsy: reversal of cortical hyperexcitability by anticonvulsants publication-title: Ann. Neurol. doi: 10.1002/ana.410340308 contributor: fullname: Reutens – volume: 39 start-page: 1839 year: 2008 ident: 10.1016/j.eplepsyres.2011.12.008_bib0280 article-title: Changes in activity of striato-thalamo-cortical network precede generalized spike wave discharges publication-title: Neuroimage doi: 10.1016/j.neuroimage.2007.10.058 contributor: fullname: Moeller – volume: 75 start-page: 154 year: 2007 ident: 10.1016/j.eplepsyres.2011.12.008_bib0455 article-title: Common and specific genetic influences on EEG power bands delta, theta, alpha, and beta publication-title: Biol. Psychol. doi: 10.1016/j.biopsycho.2007.01.004 contributor: fullname: Zietsch – volume: 7 start-page: 191 year: 1990 ident: 10.1016/j.eplepsyres.2011.12.008_bib0210 article-title: Beta and mu rhythms publication-title: J. Clin. Neurophysiol. doi: 10.1097/00004691-199004000-00004 contributor: fullname: Kozelka – volume: 38 start-page: 797 year: 1997 ident: 10.1016/j.eplepsyres.2011.12.008_bib0235 article-title: Consistent EEG focalities detected in subjects with primary generalized epilepsies monitored for two decades publication-title: Epilepsia doi: 10.1111/j.1528-1157.1997.tb01467.x contributor: fullname: Lombroso – volume: 23 start-page: 53 year: 2004 ident: 10.1016/j.eplepsyres.2011.12.008_bib0355 article-title: Estimation of multiscale neurophysiologic parameters by electroencephalographic means publication-title: Hum. Brain Mapp. doi: 10.1002/hbm.20032 contributor: fullname: Robinson – volume: 63 start-page: 815 year: 2001 ident: 10.1016/j.eplepsyres.2011.12.008_bib0260 article-title: On the cellular and network bases of epileptic seizures publication-title: Annu. Rev. Physiol. doi: 10.1146/annurev.physiol.63.1.815 contributor: fullname: McCormick – volume: 28 start-page: 193 year: 1997 ident: 10.1016/j.eplepsyres.2011.12.008_bib0165 article-title: Long-term studies on patients with absence and bilateral spike–wave complexes: 430 patients, up to 52 years follow-up publication-title: Clin. Electroencephalogr. doi: 10.1177/155005949702800403 contributor: fullname: Hughes – volume: 28 start-page: 1023 year: 2007 ident: 10.1016/j.eplepsyres.2011.12.008_bib0220 article-title: Temporal lobe interictal epileptic discharges affect cerebral activity in “default mode” brain regions publication-title: Hum. Brain Mapp. doi: 10.1002/hbm.20323 contributor: fullname: Laufs – start-page: 293 year: 1984 ident: 10.1016/j.eplepsyres.2011.12.008_bib0360 article-title: Sleep deprivation and epileptological implications contributor: fullname: Rodin – volume: 122 start-page: 2101 year: 1999 ident: 10.1016/j.eplepsyres.2011.12.008_bib0450 article-title: Abnormal cerebral structure in juvenile myoclonic epilepsy demonstrated with voxel-based analysis of MRI publication-title: Brain doi: 10.1093/brain/122.11.2101 contributor: fullname: Woermann – year: 2010 ident: 10.1016/j.eplepsyres.2011.12.008_bib0430 article-title: Connectivity of the supplementary motor area in juvenile myoclonic epilepsy and frontal lobe epilepsy publication-title: Epilepsia contributor: fullname: Vulliemoz – volume: 50 start-page: 2549 year: 2009 ident: 10.1016/j.eplepsyres.2011.12.008_bib0190 article-title: Structures involved at the time of temporal lobe spikes revealed by inter-individual group analysis of EEG/fMRI data publication-title: Epilepsia doi: 10.1111/j.1528-1167.2009.02180.x contributor: fullname: Kobayashi – volume: 1188 start-page: 207 year: 2008 ident: 10.1016/j.eplepsyres.2011.12.008_bib0005 article-title: Does spatiotemporal synchronization of EEG change prior to absence seizures? publication-title: Brain Res. doi: 10.1016/j.brainres.2007.10.048 contributor: fullname: Aarabi – volume: 92 start-page: 20 year: 1986 ident: 10.1016/j.eplepsyres.2011.12.008_bib0205 article-title: Neuronal sensitivity to GABA and glutamate in generalised epilepsy with spike and wave discharges publication-title: Exp. Neurol. doi: 10.1016/0014-4886(86)90122-6 contributor: fullname: Kostopoulos – volume: 60 start-page: 312 year: 1985 ident: 10.1016/j.eplepsyres.2011.12.008_bib0110 article-title: Test–retest reliability of spectral parameters of the EEG publication-title: Electroencephalogr. Clin. Neurophysiol. doi: 10.1016/0013-4694(85)90005-7 contributor: fullname: Gasser – start-page: 45 year: 1982 ident: 10.1016/j.eplepsyres.2011.12.008_bib0125 article-title: Neurophysiological genetic and biochemical nature of the epileptic diathesis contributor: fullname: Gloor – volume: 48 start-page: 941 year: 2007 ident: 10.1016/j.eplepsyres.2011.12.008_bib0080 article-title: Characteristic distribution of interictal brain electrical activity in idiopathic generalized epilepsy publication-title: Epilepsia doi: 10.1111/j.1528-1167.2007.01030.x contributor: fullname: Clemens – volume: 50 start-page: 1191 year: 2009 ident: 10.1016/j.eplepsyres.2011.12.008_bib0225 article-title: Magnetic resonance spectroscopy reveals an epileptic network in juvenile myoclonic epilepsy publication-title: Epilepsia doi: 10.1111/j.1528-1167.2008.01948.x contributor: fullname: Lin – volume: 29 start-page: 169 year: 1999 ident: 10.1016/j.eplepsyres.2011.12.008_bib0185 article-title: EEG alpha and theta oscillations reflect cognitive and memory performance: a review and analysis publication-title: Brain Res. Brain Res. Rev. doi: 10.1016/S0165-0173(98)00056-3 contributor: fullname: Klimesch – volume: 94 start-page: 319 year: 1994 ident: 10.1016/j.eplepsyres.2011.12.008_bib0420 article-title: Genetics of the human electroencephalogram (EEG) and event-related brain potentials (ERPs): a review publication-title: Hum. Genet. doi: 10.1007/BF00201587 contributor: fullname: van Beijsterveldt – volume: 118 start-page: 910 year: 2007 ident: 10.1016/j.eplepsyres.2011.12.008_bib0085 article-title: Lamotrigine decreases EEG synchronization in a use-dependent manner in patients with idiopathic generalized epilepsy publication-title: Clin. Neurophysiol. doi: 10.1016/j.clinph.2006.11.016 contributor: fullname: Clemens – start-page: 51 year: 1991 ident: 10.1016/j.eplepsyres.2011.12.008_bib0240 article-title: Conceptual considerations contributor: fullname: Lüders – volume: 150 start-page: 143 year: 2005 ident: 10.1016/j.eplepsyres.2011.12.008_bib0175 article-title: From synchronous neuronal discharges to subjective awareness? publication-title: Prog. Brain Res. doi: 10.1016/S0079-6123(05)50011-6 contributor: fullname: John – volume: 45 start-page: 467 year: 2004 ident: 10.1016/j.eplepsyres.2011.12.008_bib0250 article-title: Genetic architecture of idiopathic generalized epilepsy: clinical genetic analysis of 55 multiplex families publication-title: Epilepsia doi: 10.1111/j.0013-9580.2004.46803.x contributor: fullname: Marini |
SSID | ssj0007044 |
Score | 2.1446698 |
Snippet | Summary Objective We tested the hypothesis that the cortical areas with abnormal local EEG synchronization are dissimilar in the three common idiopathic... We tested the hypothesis that the cortical areas with abnormal local EEG synchronization are dissimilar in the three common idiopathic generalized epilepsy... OBJECTIVEWe tested the hypothesis that the cortical areas with abnormal local EEG synchronization are dissimilar in the three common idiopathic generalized... |
SourceID | proquest crossref pubmed pascalfrancis elsevier |
SourceType | Aggregation Database Index Database Publisher |
StartPage | 281 |
SubjectTerms | Absence Adolescent Anticonvulsants. Antiepileptics. Antiparkinson agents Biological and medical sciences EEG Electroencephalography - methods Electromagnetic Phenomena Endophenotype Endophenotypes Epilepsy, Generalized - diagnosis Epilepsy, Generalized - physiopathology Female Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Humans Juvenile myoclonic epilepsy LORETA Male Medical sciences Nervous system (semeiology, syndromes) Neurology Neuropharmacology Pharmacology. Drug treatments Tomography - methods Young Adult |
Title | EEG-LORETA endophenotypes of the common idiopathic generalized epilepsy syndromes |
URI | https://www.clinicalkey.es/playcontent/1-s2.0-S0920121111004153 https://dx.doi.org/10.1016/j.eplepsyres.2011.12.008 https://www.ncbi.nlm.nih.gov/pubmed/22240326 https://search.proquest.com/docview/1010635265 |
Volume | 99 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1ba9RAFD6UCiKItPXSWLuMIH1q3FwnG3xaytb10lp1C30bJpkTiUgSnO3D-uBv98xM0lBUEHzMMrOZnMuc78ycC8CLQBZxocg74THnfoJV5hfcHIcVaajoKYvtRfvZOV9eJm-v0qstOBlyYUxYZb_3uz3d7tb9L9OemtOurqefgzyyBcps0TNSXJPBTsaIZPrlzzHMIwtsQ1cz2Dej-2geF-OF3Tfs9IYcW1fM0xwMmkaTfzZR9zupiXCV63jxd0hqTdPpDjzoMSWbu2XvwhY2e3D3rL8134OjC1efenPMVmO6lT5mR-xirFy9eQgfF4vX_vsPnxarOcNGmZIDTWsOaTVrK0ZQkRGZSG5ZrerW9jIu2RdXt7r-gYphV9svZUMdBP0ILk8Xq5Ol3_dc8Mskzdc-loQoQplUCZ9lihepVGTDJDltSJoseUkABblCcrNQkfWPMIhJi1MZxmUsqyh-DNtN2-A-MFQm7zXHvCrIDSny2SzJA5qcJjLnUsYehAOZRedKa4gh5uyrGFkjDGtEGAlijQfZwA8xpI7SZoe61zwtQqFppPhNOjx4dTPzloAJsh3_8N7JLebfLDgyib5EBw-eD9IgSEHNrYtssL3W5n8JBpouBB48cWIyzjaAigD00_9a3AHcM9_qwjCfwfb6-zUeElRaFxOrCxO4M3_zbnn-C0JIEx8 |
link.rule.ids | 315,786,790,4521,24144,27955,27956,45618,45712 |
linkProvider | Elsevier |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1Lb9QwEB6VIgESQlBe4VGMhHpqunk6G3Gqqi0L7JYCW6k3y4knKAglEd4elgO_nbGdNKoACYljVvbGmYfnG3seAK8CWcSFIu-Ex5z7CVaZX3BzHFakoaKnLLYX7csTPj9L3p2n51twNOTCmLDKfu93e7rdrftfJj01J11dTz4HeWQLlNmiZ6S41-C6QQMmruvg5xjnkQW2o6sZ7ZvhfTiPC_LC7ht2ekOeravmaU4GTafJP9uo253URLnKtbz4Oya1tun4LtzpQSU7dOu-B1vY7MCNZX9tvgN7p65A9WafrcZ8K73P9tjpWLp6cx8-zmZv_MWHT7PVIcNGmZoDTWtOaTVrK0ZYkRGdSHBZrerWNjMu2RdXuLr-gYphV9svZUMhBP0Azo5nq6O53zdd8Mskzdc-lgQpQplUCZ9mihepVGTEJHltSKoseUkIBblC8rNQkfmPMIhJjVMZxmUsqyh-CNtN2-BjYKhM4muOeVWQH1Lk02mSBzQ5TWTOpYw9CAcyi87V1hBD0NlXMbJGGNaIMBLEGg-ygR9iyB2l3Q51r3pahELTSPGbeHjw-nLmFQkTZDz-4b27V5h_ueDIZPoSHTx4OUiDIA011y6ywfZCm_8lHGjaEHjwyInJONsgKkLQT_5rcS_g5ny1XIjF25P3T-GW-W4Xk_kMttffL_A54aZ1sWv14heGjxS4 |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=EEG-LORETA+endophenotypes+of+the+common+idiopathic+generalized+epilepsy+syndromes&rft.jtitle=Epilepsy+research&rft.au=Clemens%2C+B.&rft.au=Pusk%C3%A1s%2C+S.&rft.au=Besenyei%2C+M.&rft.au=Emri%2C+M.&rft.date=2012-05-01&rft.pub=Elsevier+B.V&rft.issn=0920-1211&rft.eissn=1872-6844&rft.volume=99&rft.issue=3&rft.spage=281&rft.epage=292&rft_id=info:doi/10.1016%2Fj.eplepsyres.2011.12.008&rft.externalDocID=S0920121111004153 |
thumbnail_m | http://utb.summon.serialssolutions.com/2.0.0/image/custom?url=https%3A%2F%2Fcdn.clinicalkey.com%2Fck-thumbnails%2F09201211%2FS0920121112X00044%2Fcov150h.gif |