Clinical Characteristics and Outcomes of Hospitalized and Critically Ill Children and Adolescents with Coronavirus Disease 2019 at a Tertiary Care Medical Center in New York City
To describe the clinical profiles and risk factors for critical illness in hospitalized children and adolescents with coronavirus disease 2019 (COVID-19). Children 1 month to 21 years of age with COVID-19 from a single tertiary care children's hospital between March 15 and April 13, 2020 were i...
Saved in:
Published in | The Journal of pediatrics Vol. 223; pp. 14 - 19.e2 |
---|---|
Main Authors | , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
United States
Elsevier Inc
01.08.2020
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | To describe the clinical profiles and risk factors for critical illness in hospitalized children and adolescents with coronavirus disease 2019 (COVID-19).
Children 1 month to 21 years of age with COVID-19 from a single tertiary care children's hospital between March 15 and April 13, 2020 were included. Demographic and clinical data were collected.
In total, 67 children tested positive for COVID-19; 21 (31.3%) were managed as outpatients. Of 46 admitted patients, 33 (72%) were admitted to the general pediatric medical unit and 13 (28%) to the pediatric intensive care unit (PICU). Obesity and asthma were highly prevalent but not significantly associated with PICU admission (P = .99). Admission to the PICU was significantly associated with higher C-reactive protein, procalcitonin, and pro-B type natriuretic peptide levels and platelet counts (P < .05 for all). Patients in the PICU were more likely to require high-flow nasal cannula (P = .0001) and were more likely to have received Remdesivir through compassionate release (P < .05). Severe sepsis and septic shock syndromes were observed in 7 (53.8%) patients in the PICU. Acute respiratory distress syndrome was observed in 10 (77%) PICU patients, 6 of whom (46.2%) required invasive mechanical ventilation for a median of 9 days. Of the 13 patients in the PICU, 8 (61.5%) were discharged home, and 4 (30.7%) patients remain hospitalized on ventilatory support at day 14. One patient died after withdrawal of life-sustaining therapy because of metastatic cancer.
We describe a higher than previously recognized rate of severe disease requiring PICU admission in pediatric patients admitted to the hospital with COVID-19. |
---|---|
AbstractList | To describe the clinical profiles and risk factors for critical illness in hospitalized children and adolescents with coronavirus disease 2019 (COVID-19).
Children 1 month to 21 years of age with COVID-19 from a single tertiary care children's hospital between March 15 and April 13, 2020 were included. Demographic and clinical data were collected.
In total, 67 children tested positive for COVID-19; 21 (31.3%) were managed as outpatients. Of 46 admitted patients, 33 (72%) were admitted to the general pediatric medical unit and 13 (28%) to the pediatric intensive care unit (PICU). Obesity and asthma were highly prevalent but not significantly associated with PICU admission (P = .99). Admission to the PICU was significantly associated with higher C-reactive protein, procalcitonin, and pro-B type natriuretic peptide levels and platelet counts (P < .05 for all). Patients in the PICU were more likely to require high-flow nasal cannula (P = .0001) and were more likely to have received Remdesivir through compassionate release (P < .05). Severe sepsis and septic shock syndromes were observed in 7 (53.8%) patients in the PICU. Acute respiratory distress syndrome was observed in 10 (77%) PICU patients, 6 of whom (46.2%) required invasive mechanical ventilation for a median of 9 days. Of the 13 patients in the PICU, 8 (61.5%) were discharged home, and 4 (30.7%) patients remain hospitalized on ventilatory support at day 14. One patient died after withdrawal of life-sustaining therapy because of metastatic cancer.
We describe a higher than previously recognized rate of severe disease requiring PICU admission in pediatric patients admitted to the hospital with COVID-19. |
Author | Chao, Jerry Y. Aldrich, Margaret Weingarten, Jacqueline Derespina, Kim R. Goldman, David L. Cabana, Michael D. Ushay, Henry M. Herold, Betsy C. Medar, Shivanand S. |
Author_xml | – sequence: 1 givenname: Jerry Y. surname: Chao fullname: Chao, Jerry Y. organization: Department of Anesthesiology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY – sequence: 2 givenname: Kim R. surname: Derespina fullname: Derespina, Kim R. organization: Division of Critical Care Medicine, Department of Pediatrics, Albert Einstein College of Medicine, Children's Hospital at Montefiore, Bronx, NY – sequence: 3 givenname: Betsy C. surname: Herold fullname: Herold, Betsy C. organization: Division of Infectious Diseases, Department of Pediatrics, Albert Einstein College of Medicine, Children's Hospital at Montefiore, Bronx, NY – sequence: 4 givenname: David L. surname: Goldman fullname: Goldman, David L. organization: Division of Infectious Diseases, Department of Pediatrics, Albert Einstein College of Medicine, Children's Hospital at Montefiore, Bronx, NY – sequence: 5 givenname: Margaret surname: Aldrich fullname: Aldrich, Margaret organization: Division of Infectious Diseases, Department of Pediatrics, Albert Einstein College of Medicine, Children's Hospital at Montefiore, Bronx, NY – sequence: 6 givenname: Jacqueline surname: Weingarten fullname: Weingarten, Jacqueline organization: Division of Critical Care Medicine, Department of Pediatrics, Albert Einstein College of Medicine, Children's Hospital at Montefiore, Bronx, NY – sequence: 7 givenname: Henry M. surname: Ushay fullname: Ushay, Henry M. organization: Division of Critical Care Medicine, Department of Pediatrics, Albert Einstein College of Medicine, Children's Hospital at Montefiore, Bronx, NY – sequence: 8 givenname: Michael D. surname: Cabana fullname: Cabana, Michael D. organization: Division of General Pediatrics, Department of Pediatrics, Albert Einstein College of Medicine, Children's Hospital at Montefiore, Bronx, NY – sequence: 9 givenname: Shivanand S. surname: Medar fullname: Medar, Shivanand S. email: shivanandmedar@gmail.com organization: Division of Critical Care Medicine, Department of Pediatrics, Albert Einstein College of Medicine, Children's Hospital at Montefiore, Bronx, NY |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/32407719$$D View this record in MEDLINE/PubMed |
BookMark | eNp9kc1uEzEUhS1URNPCEyAhv8AM154fxwuQquGnlQrdlAUry2PfIQ4TO7KdVOGxeEJmEqhgw8qLc79z7_G5IGc-eCTkJYOSAWtfr8v1Fm0qOXAooSkB2idkwUCKol1W1RlZAHBeVLVoz8lFSmsAkDXAM3Je8RqEYHJBfnaj887okXYrHbXJGF3KziSqvaV3u2zCBhMNA70OaeuyHt0PtEexiy7P5HigN-PMu9FG9EftyoYRk0GfE31weUW7EIPXexd3ib5zCXVCyoFJqjPV9B5jdjoeaKcj0k9oTxdNOEbqPP2MD_RriN9p5_LhOXk66DHhi9_vJfny4f19d13c3n286a5uC1M3MhcGp7hC1KZqlr2xuqkrawbJbC_kwITVrVgOhg2NrHEAaAbgUlQMjTA98F5Xl-TtyXe76zdo5zBRj2ob3WY6VQXt1L-Kdyv1LeyV4IzLWkwG1cnAxJBSxOGRZaDmCtVaHStUc4UKGjVVOFGv_l77yPzpbBp4cxrAKfzeYVTJOPRm-rWIJisb3H8X_AK7E7Q9 |
CitedBy_id | crossref_primary_10_1515_med_2024_0923 crossref_primary_10_3389_fped_2020_603741 crossref_primary_10_1002_ppul_24989 crossref_primary_10_1016_j_hnm_2024_200265 crossref_primary_10_29333_ejgm_11019 crossref_primary_10_1097_MD_0000000000022571 crossref_primary_10_1371_journal_pone_0273842 crossref_primary_10_1080_20469047_2021_1888026 crossref_primary_10_1097_PCC_0000000000002599 crossref_primary_10_1542_peds_2020_032888 crossref_primary_10_3390_children8110951 crossref_primary_10_1002_jmv_26684 crossref_primary_10_26453_otjhs_798631 crossref_primary_10_1097_IPC_0000000000000973 crossref_primary_10_3346_jkms_2022_37_e13 crossref_primary_10_1002_ppul_24981 crossref_primary_10_1055_s_0041_1735215 crossref_primary_10_1007_s12519_022_00515_7 crossref_primary_10_1371_journal_pone_0268388 crossref_primary_10_1055_a_1263_1222 crossref_primary_10_1016_j_eclinm_2022_101287 crossref_primary_10_3389_fped_2021_649358 crossref_primary_10_1177_13623613231155265 crossref_primary_10_1016_j_jpeds_2020_07_039 crossref_primary_10_1177_00185787231220318 crossref_primary_10_21307_PM_2020_59_3_15 crossref_primary_10_4274_csmedj_galenos_2022_2022_11_10 crossref_primary_10_1038_s41598_024_55065_x crossref_primary_10_1016_j_prrv_2020_07_003 crossref_primary_10_2139_ssrn_3731450 crossref_primary_10_1111_apa_15962 crossref_primary_10_1186_s13052_023_01536_2 crossref_primary_10_2214_AJR_20_24032 crossref_primary_10_1371_journal_pone_0263267 crossref_primary_10_1093_jpids_piad116 crossref_primary_10_2500_aap_2021_42_210087 crossref_primary_10_5812_pedinfect_116282 crossref_primary_10_4049_jimmunol_2001449 crossref_primary_10_1097_MD_0000000000026709 crossref_primary_10_1097_ACI_0000000000000724 crossref_primary_10_1016_j_metabol_2020_154378 crossref_primary_10_1007_s12519_023_00790_y crossref_primary_10_4103_NJM_NJM_183_20 crossref_primary_10_1177_2333794X221085386 crossref_primary_10_1111_obr_13165 crossref_primary_10_1177_00099228211059883 crossref_primary_10_7759_cureus_14825 crossref_primary_10_1016_j_jcv_2022_105220 crossref_primary_10_1093_jpids_piaa099 crossref_primary_10_6061_clinics_2021_e3488 crossref_primary_10_1016_j_jiac_2021_08_020 crossref_primary_10_1111_obr_13616 crossref_primary_10_15585_mmwr_mm705152a3 crossref_primary_10_1002_art_41616 crossref_primary_10_1093_jpids_piaa095 crossref_primary_10_3390_v16050779 crossref_primary_10_1136_bmjopen_2021_055430 crossref_primary_10_1002_pbc_28693 crossref_primary_10_1007_s00415_020_10339_y crossref_primary_10_12793_tcp_2022_30_e4 crossref_primary_10_1186_s12889_021_11546_6 crossref_primary_10_4103_jfmpc_jfmpc_2583_20 crossref_primary_10_1097_INF_0000000000003169 crossref_primary_10_1007_s10049_021_00887_9 crossref_primary_10_6061_clinics_2020_e2273 crossref_primary_10_20961_plexus_v3i1_1103 crossref_primary_10_1002_ppul_25514 crossref_primary_10_31362_patd_1114808 crossref_primary_10_1016_j_heliyon_2020_e05635 crossref_primary_10_1097_INF_0000000000003166 crossref_primary_10_1055_s_0040_1721513 crossref_primary_10_1097_INF_0000000000003043 crossref_primary_10_1038_s41598_021_86694_1 crossref_primary_10_1111_jpc_15737 crossref_primary_10_1177_0009922820944399 crossref_primary_10_1111_apa_15499 crossref_primary_10_9778_cmajo_20220072 crossref_primary_10_2337_dbi20_0032 crossref_primary_10_1093_rheumatology_keac103 crossref_primary_10_1002_ppul_25642 crossref_primary_10_4103_atm_atm_709_20 crossref_primary_10_1007_s12016_022_08921_5 crossref_primary_10_1111_pai_13696 crossref_primary_10_1016_j_cytogfr_2022_10_003 crossref_primary_10_1111_all_14452 crossref_primary_10_1016_j_idc_2021_11_002 crossref_primary_10_3390_children9050634 crossref_primary_10_1371_journal_pone_0283037 crossref_primary_10_1016_j_vaccine_2021_01_022 crossref_primary_10_1177_2333794X231220873 crossref_primary_10_1002_ppul_25087 crossref_primary_10_1097_MPA_0000000000001923 crossref_primary_10_1148_ryct_2020200346 crossref_primary_10_12688_f1000research_126156_1 crossref_primary_10_36316_gcatr_02_0032 crossref_primary_10_1002_cpt_2176 crossref_primary_10_1007_s00467_020_04724_y crossref_primary_10_4103_jrnm_jrnm_14_20 crossref_primary_10_1016_j_ijid_2020_11_163 crossref_primary_10_3389_fped_2021_668484 crossref_primary_10_1016_j_resuscitation_2021_02_015 crossref_primary_10_1186_s12879_023_08720_z crossref_primary_10_1002_pbc_29075 crossref_primary_10_1542_hpeds_2020_001917 crossref_primary_10_1186_s12887_020_02471_5 crossref_primary_10_1002_jmv_27237 crossref_primary_10_1186_s43168_022_00110_4 crossref_primary_10_2500_aap_2021_42_210041 crossref_primary_10_1097_QCO_0000000000000762 crossref_primary_10_1007_s40519_021_01269_3 crossref_primary_10_3346_jkms_2022_37_e35 crossref_primary_10_1001_jamapediatrics_2020_3996 crossref_primary_10_1002_ppul_26184 crossref_primary_10_1542_peds_2020_047803 crossref_primary_10_3346_jkms_2021_36_e339 crossref_primary_10_1016_j_jped_2021_12_006 crossref_primary_10_1093_jpids_piaa175 crossref_primary_10_2147_IJGM_S311831 crossref_primary_10_7759_cureus_58307 crossref_primary_10_1002_art_41772 crossref_primary_10_1016_j_anai_2020_11_021 crossref_primary_10_1016_j_pedneo_2022_09_014 crossref_primary_10_1007_s00246_020_02476_y crossref_primary_10_1016_j_cmi_2020_12_018 crossref_primary_10_5812_jcp_137674 crossref_primary_10_3389_fmed_2020_572485 crossref_primary_10_1093_tropej_fmac105 crossref_primary_10_24018_ejmed_2022_4_2_1304 crossref_primary_10_1093_jpids_piac107 crossref_primary_10_5005_jp_journals_10071_24145 crossref_primary_10_1016_j_ppedcard_2022_101507 crossref_primary_10_1002_art_42062 crossref_primary_10_3390_biomedicines12040905 crossref_primary_10_1016_j_it_2020_10_004 crossref_primary_10_3346_jkms_2021_36_e203 crossref_primary_10_3389_fdgth_2023_1193467 crossref_primary_10_1016_j_amepre_2020_07_021 crossref_primary_10_1016_j_biopsych_2020_12_014 crossref_primary_10_1186_s40246_022_00392_1 crossref_primary_10_3389_fonc_2020_608282 crossref_primary_10_1097_MOP_0000000000001018 crossref_primary_10_1016_j_eclinm_2021_101155 crossref_primary_10_1097_PCC_0000000000002512 crossref_primary_10_1177_2333794X211022710 crossref_primary_10_1371_journal_pone_0305001 crossref_primary_10_6061_clinics_2020_e2353 crossref_primary_10_1097_MOP_0000000000000971 crossref_primary_10_1016_j_obmed_2021_100327 crossref_primary_10_1002_oby_23223 crossref_primary_10_1055_s_0041_1730967 crossref_primary_10_1016_j_pedneo_2023_02_009 crossref_primary_10_1016_j_jpeds_2021_06_002 crossref_primary_10_1055_s_0041_1732345 crossref_primary_10_1111_pai_13536 crossref_primary_10_1542_hpeds_2022_006613 crossref_primary_10_17343_sdutfd_906828 crossref_primary_10_1097_PCC_0000000000003156 crossref_primary_10_1001_jamanetworkopen_2021_12596 crossref_primary_10_15585_mmwr_mm6932e3 crossref_primary_10_1177_0009922820941631 crossref_primary_10_3390_life11030247 crossref_primary_10_36106_ijar_6212323 crossref_primary_10_14238_pi62_6_2022_411_21 crossref_primary_10_4168_aard_2022_10_4_219 crossref_primary_10_1016_j_jiph_2023_06_017 crossref_primary_10_1111_ijpo_12920 crossref_primary_10_1186_s13052_021_01198_y crossref_primary_10_1038_s41598_023_33314_9 crossref_primary_10_1055_a_2250_3166 crossref_primary_10_1097_MOP_0000000000000983 crossref_primary_10_1371_journal_pone_0288284 crossref_primary_10_17343_sdutfd_907236 crossref_primary_10_2174_1573396316999201123200936 crossref_primary_10_1093_jpids_piaa115 crossref_primary_10_1002_pbc_28745 crossref_primary_10_1590_1806_9304202100s100017 crossref_primary_10_21292_2078_5658_2021_18_4_29_36 crossref_primary_10_1002_art_41454 crossref_primary_10_1007_s11908_020_00739_6 crossref_primary_10_1093_rheumatology_keac408 crossref_primary_10_1093_jpids_piae052 crossref_primary_10_1017_S0950268820003027 crossref_primary_10_15690_pf_v18i4_2295 crossref_primary_10_1016_j_ajem_2021_01_072 crossref_primary_10_1542_peds_2020_044685 crossref_primary_10_1016_j_jaci_2020_07_026 crossref_primary_10_1152_ajplung_00259_2020 crossref_primary_10_1002_ppul_25344 crossref_primary_10_1038_s41422_021_00495_9 crossref_primary_10_1016_j_ccm_2022_11_014 crossref_primary_10_1038_s41366_021_00776_8 crossref_primary_10_1002_rcr2_1012 crossref_primary_10_1016_j_jiac_2022_06_010 crossref_primary_10_1183_23120541_00409_2020 crossref_primary_10_3389_fimmu_2023_1159269 crossref_primary_10_1016_j_biopha_2022_113804 crossref_primary_10_1016_j_jpeds_2020_06_045 crossref_primary_10_1080_14740338_2021_1962284 crossref_primary_10_12998_wjcc_v8_i21_5250 crossref_primary_10_14238_pi62_1_2022_51_60 crossref_primary_10_3166_afmu_2020_0257 crossref_primary_10_1016_j_cmpb_2021_106301 crossref_primary_10_1016_j_acci_2021_08_002 crossref_primary_10_1002_ppul_25245 crossref_primary_10_5812_pedinfect_132819 crossref_primary_10_7759_cureus_29061 crossref_primary_10_1097_MD_0000000000028499 crossref_primary_10_1097_ANA_0000000000000803 crossref_primary_10_1542_peds_2020_003186 crossref_primary_10_1016_j_pcl_2022_01_013 crossref_primary_10_1016_j_jemermed_2021_07_070 crossref_primary_10_18678_dtfd_1098928 crossref_primary_10_1016_j_clnesp_2022_04_005 crossref_primary_10_1155_2021_6620240 crossref_primary_10_1136_archdischild_2020_321385 crossref_primary_10_3390_nu13124255 crossref_primary_10_1111_jth_15216 crossref_primary_10_1111_ped_14602 crossref_primary_10_1055_s_0041_1741371 crossref_primary_10_3389_fmats_2022_1059184 crossref_primary_10_1155_2021_5558287 crossref_primary_10_1542_peds_2021_052273 crossref_primary_10_4103_rcm_rcm_39_22 crossref_primary_10_1097_INF_0000000000003433 crossref_primary_10_1017_S1047951122000397 crossref_primary_10_1080_14656566_2021_1883586 crossref_primary_10_3390_ijerph18031093 crossref_primary_10_57221_izmirtip_1160180 crossref_primary_10_1007_s44253_024_00041_6 crossref_primary_10_1016_j_jpeds_2020_05_022 crossref_primary_10_1016_j_jaip_2021_12_044 crossref_primary_10_1002_jmv_26677 crossref_primary_10_1016_j_jpeds_2020_11_016 crossref_primary_10_1371_journal_pone_0256784 crossref_primary_10_3389_fimmu_2023_1183489 crossref_primary_10_1016_j_pcl_2020_07_014 crossref_primary_10_1097_MD_0000000000024315 crossref_primary_10_1186_s12879_023_08357_y crossref_primary_10_26453_otjhs_775502 |
Cites_doi | 10.1186/cc11454 10.1016/j.jaci.2017.01.036 10.1097/PCC.0000000000001695 10.1001/jama.2020.4326 10.1056/NEJM200005043421801 10.1001/jama.2020.1585 10.1016/S0140-6736(20)30211-7 10.1001/jama.2020.5394 10.1542/peds.2019-0748 10.1542/peds.2020-0702 10.1016/S2213-2600(20)30079-5 10.1016/S0140-6736(20)30183-5 10.1007/s11113-008-9115-4 10.1056/NEJMoa2004500 10.1056/NEJMc2003717 10.1097/PCC.0000000000002198 10.1016/S1473-3099(20)30198-5 10.1542/peds.109.1.40 10.1056/NEJMoa2002032 10.1056/NEJMc2005073 |
ContentType | Journal Article |
Copyright | 2020 Elsevier Inc. Copyright © 2020 Elsevier Inc. All rights reserved. 2020 Elsevier Inc. All rights reserved. 2020 Elsevier Inc. |
Copyright_xml | – notice: 2020 Elsevier Inc. – notice: Copyright © 2020 Elsevier Inc. All rights reserved. – notice: 2020 Elsevier Inc. All rights reserved. 2020 Elsevier Inc. |
DBID | CGR CUY CVF ECM EIF NPM AAYXX CITATION 5PM |
DOI | 10.1016/j.jpeds.2020.05.006 |
DatabaseName | Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef PubMed Central (Full Participant titles) |
DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef |
DatabaseTitleList | MEDLINE |
Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine |
EISSN | 1097-6833 |
EndPage | 19.e2 |
ExternalDocumentID | 10_1016_j_jpeds_2020_05_006 32407719 S0022347620305801 |
Genre | Journal Article Research Support, N.I.H., Extramural |
GeographicLocations | New York City |
GeographicLocations_xml | – name: New York City |
GrantInformation_xml | – fundername: Montefiore Medical Center – fundername: NIH funderid: https://doi.org/10.13039/100000002 – fundername: NCATS funderid: https://doi.org/10.13039/100006108 – fundername: Albert Einstein College of Medicine funderid: https://doi.org/10.13039/100007319 – fundername: Departments of Anesthesiology and Pediatrics – fundername: NCATS NIH HHS grantid: UL1 TR001073 – fundername: NCATS NIH HHS grantid: UL1 TR002556 |
GroupedDBID | --- --K --M -ET -RU .1- .55 .FO .GJ .XZ .~1 0R~ 123 1B1 1CY 1P~ 1RT 1~. 1~5 354 3O- 4.4 41~ 457 4G. 53G 5RE 5VS 7-5 85S 8P~ 9JM AACTN AAEDT AAEDW AAEJM AAIAV AAIKC AAIKJ AAKOC AALRI AAMNW AAOAW AAQFI AAQQT AAQXK AAWTL AAXUO AAYJJ ABBQC ABFNM ABFRF ABIVO ABJNI ABLJU ABLVK ABMAC ABMZM ABOCM ABPPZ ABXDB ABYKQ ACDAQ ACGFO ACGFS ACNCT ACRLP ACRZS ADBBV ADEZE ADMUD AEBSH AEFWE AEKER AENEX AEVXI AFDAS AFFNX AFKWA AFRHN AFTJW AFXIZ AGHFR AGNAY AGUBO AGYEJ AHHHB AHPSJ AI. AIEXJ AIKHN AITUG AJBFU AJJEV AJOXV AJRQY AJUYK ALMA_UNASSIGNED_HOLDINGS AMFUW AMRAJ ANZVX ASPBG AVWKF AXJTR AZFZN BKOJK BLXMC BNPGV C45 C5W CAG COF CS3 DU5 EBS EFJIC EFLBG EJD EX3 F5P FDB FEDTE FGOYB FIRID FNPLU FYGXN G-2 G-Q G8K GBLVA HEF HMK HMO HVGLF HZ~ IHE J1W K-O KOM L7B LCYCR M27 M32 M41 MO0 N4W N9A NEJ NQ- O-L O9- OAUVE OB2 OBH OH- OHH OHT OT- OVD P-8 P-9 P2P PC. PQQKQ Q38 R2- RIG ROL RPZ SAE SDF SEL SES SEW SJN SPCBC SSH SSZ T5K TEORI TWZ UGJ UHB UHS UKR UV1 VH1 VVN WH7 WOW WUQ X7M XCE XFW XOL YCJ YFH YOC YOJ YQJ YZZ Z5R ZA5 ZGI ZQV ZXP ZY1 ~G- ~KM AAXKI AFCTW AFJKZ AKRWK CGR CUY CVF ECM EIF NPM AAYXX ABDPE ACRPL ADNMO CITATION 5PM |
ID | FETCH-LOGICAL-c459t-ce009774c358bcda543dcf91db79f17da678fc1f594ef005f029731ec7cb02ba3 |
IEDL.DBID | .~1 |
ISSN | 0022-3476 |
IngestDate | Tue Sep 17 21:06:54 EDT 2024 Fri Dec 06 06:33:40 EST 2024 Sat Sep 28 08:34:01 EDT 2024 Fri Feb 23 02:47:48 EST 2024 |
IsDoiOpenAccess | true |
IsOpenAccess | true |
IsPeerReviewed | true |
IsScholarly | true |
Keywords | COVID-19 SARS-CoV-2 children critical care SARS CoV-2 ICU ARDS PICU ED |
Language | English |
License | Copyright © 2020 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
LinkModel | DirectLink |
MergedId | FETCHMERGED-LOGICAL-c459t-ce009774c358bcda543dcf91db79f17da678fc1f594ef005f029731ec7cb02ba3 |
Notes | Contributed equally. |
OpenAccessLink | https://pubmed.ncbi.nlm.nih.gov/PMC7212947 |
PMID | 32407719 |
ParticipantIDs | pubmedcentral_primary_oai_pubmedcentral_nih_gov_7212947 crossref_primary_10_1016_j_jpeds_2020_05_006 pubmed_primary_32407719 elsevier_sciencedirect_doi_10_1016_j_jpeds_2020_05_006 |
PublicationCentury | 2000 |
PublicationDate | 2020-08-01 |
PublicationDateYYYYMMDD | 2020-08-01 |
PublicationDate_xml | – month: 08 year: 2020 text: 2020-08-01 day: 01 |
PublicationDecade | 2020 |
PublicationPlace | United States |
PublicationPlace_xml | – name: United States |
PublicationTitle | The Journal of pediatrics |
PublicationTitleAlternate | J Pediatr |
PublicationYear | 2020 |
Publisher | Elsevier Inc |
Publisher_xml | – name: Elsevier Inc |
References | Wu, Chen, Cai, Xia, Zhou, Xu (bib20) 2020 Grunwell, Travers, Fitzpatrick (bib18) 2018; 19 Arentz, Yim, Klaff (bib23) 2020; 323 Keenan, Foster, Bratton (bib16) 2002; 109 Yang, Yu, Xu, Shu, Xia, Liu (bib12) 2020; 8 Liu, Zhang, Chen, Xiang, Song, Shu (bib4) 2020; 382 Qiu, Wu, Hong, Luo, Song, Chen (bib6) 2020; 20 Lee, Harris, Gordon-Larsen (bib15) 2009; 28 bib21 Weiss, Peters, Alhazzani, Agus MS, Flori H, Nadel (bib10) 2020; 21 Keet, Matsui, McCormack, Peng (bib17) 2017; 140 Bhatraju, Ghassemieh, Nichols, Kim, Jerome, Nalla (bib24) 2020; 382 Guan, Ni, Hu, Liang, Ou, He (bib2) 2020; 382 Tagarro, Epalza, Santos, Sanz-Santaeufemia, Otheo, Moraleda (bib7) 2020 Chen, Zhou, Dong, Qu, Gong, Han (bib14) 2020; 395 Grasselli, Zangrillo, Zanella, Antonelli, Cabrini, Castelli (bib22) 2020; 323 Kellum, Lameire (bib11) 2013; 17 Ranieri, Rubenfeld, Thompson, Ferguson, Caldwell, Fan (bib8) 2012; 307 Wang, Hu, Hu, Zhu, Liu, Zhang (bib13) 2020; 323 Andrist, Riley, Brokamp, Taylor, Beck (bib19) 2019; 144 Brower, Matthay, Morris, Schoenfeld, Thompson (bib9) 2000; 342 Huang, Wang, Li, Ren, Zhao, Hu (bib1) 2020; 395 Lu, Zhang, Du, Zhang, Li, Qu (bib3) 2020; 382 Dong, Mo, Hu, Qi, Jiang, Jiang (bib5) 2020; 145 Dong (10.1016/j.jpeds.2020.05.006_bib5) 2020; 145 Lee (10.1016/j.jpeds.2020.05.006_bib15) 2009; 28 Wang (10.1016/j.jpeds.2020.05.006_bib13) 2020; 323 Bhatraju (10.1016/j.jpeds.2020.05.006_bib24) 2020; 382 Weiss (10.1016/j.jpeds.2020.05.006_bib10) 2020; 21 Huang (10.1016/j.jpeds.2020.05.006_bib1) 2020; 395 Brower (10.1016/j.jpeds.2020.05.006_bib9) 2000; 342 Grunwell (10.1016/j.jpeds.2020.05.006_bib18) 2018; 19 Kellum (10.1016/j.jpeds.2020.05.006_bib11) 2013; 17 Arentz (10.1016/j.jpeds.2020.05.006_bib23) 2020; 323 Ranieri (10.1016/j.jpeds.2020.05.006_bib8) 2012; 307 Lu (10.1016/j.jpeds.2020.05.006_bib3) 2020; 382 Liu (10.1016/j.jpeds.2020.05.006_bib4) 2020; 382 Yang (10.1016/j.jpeds.2020.05.006_bib12) 2020; 8 Wu (10.1016/j.jpeds.2020.05.006_bib20) 2020 Chen (10.1016/j.jpeds.2020.05.006_bib14) 2020; 395 Guan (10.1016/j.jpeds.2020.05.006_bib2) 2020; 382 Qiu (10.1016/j.jpeds.2020.05.006_bib6) 2020; 20 Grasselli (10.1016/j.jpeds.2020.05.006_bib22) 2020; 323 Keet (10.1016/j.jpeds.2020.05.006_bib17) 2017; 140 Andrist (10.1016/j.jpeds.2020.05.006_bib19) 2019; 144 Tagarro (10.1016/j.jpeds.2020.05.006_bib7) 2020 Keenan (10.1016/j.jpeds.2020.05.006_bib16) 2002; 109 |
References_xml | – volume: 144 start-page: e20190748 year: 2019 ident: bib19 article-title: Neighborhood poverty and pediatric intensive care use publication-title: Pediatrics contributor: fullname: Beck – ident: bib21 – volume: 382 start-page: 2012 year: 2020 end-page: 2022 ident: bib24 article-title: Covid-19 in critically ill patients in the Seattle region—case series publication-title: N Engl J Med contributor: fullname: Nalla – volume: 145 start-page: e20200702 year: 2020 ident: bib5 article-title: Epidemiological characteristics of 2143 pediatric patients with 2019 coronavirus disease in China publication-title: Pediatrics contributor: fullname: Jiang – volume: 382 start-page: 1708 year: 2020 end-page: 1720 ident: bib2 article-title: Clinical characteristics of coronavirus disease 2019 in China publication-title: N Engl J Med contributor: fullname: He – start-page: e201346 year: 2020 ident: bib7 article-title: Screening and severity of coronavirus disease 2019 (COVID-19) in children in Madrid, Spain publication-title: JAMA Pediatr contributor: fullname: Moraleda – volume: 109 start-page: 40 year: 2002 end-page: 44 ident: bib16 article-title: Social factors associated with prolonged hospitalization among diabetic children publication-title: Pediatrics contributor: fullname: Bratton – volume: 8 start-page: 475 year: 2020 end-page: 481 ident: bib12 article-title: Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study publication-title: Lancet Respir Med contributor: fullname: Liu – volume: 307 start-page: 2526 year: 2012 end-page: 2533 ident: bib8 article-title: Acute respiratory distress syndrome: the Berlin definition publication-title: JAMA contributor: fullname: Fan – volume: 17 start-page: 204 year: 2013 ident: bib11 article-title: Diagnosis, evaluation, and management of acute kidney injury: a KDIGO summary (Part 1) publication-title: Crit Care contributor: fullname: Lameire – volume: 323 start-page: 1574 year: 2020 end-page: 1581 ident: bib22 article-title: Baseline characteristics and outcomes of 1591 patients infected with SARS-CoV-2 admitted to ICUs of the Lombardy Region, Italy publication-title: JAMA contributor: fullname: Castelli – volume: 382 start-page: 1370 year: 2020 end-page: 1371 ident: bib4 article-title: Detection of 2019-nCoV in children in early January 2020 in Wuhan, China publication-title: N Engl J Med contributor: fullname: Shu – volume: 21 start-page: e52 year: 2020 end-page: e106 ident: bib10 article-title: Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children publication-title: Pediatr Crit Care Med contributor: fullname: Nadel – volume: 382 start-page: 1663 year: 2020 end-page: 1665 ident: bib3 article-title: SARS-CoV-2 infection in children publication-title: N Engl J Med contributor: fullname: Qu – start-page: e200994 year: 2020 ident: bib20 article-title: Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China publication-title: JAMA Intern Med contributor: fullname: Xu – volume: 19 start-page: e585 year: 2018 end-page: e594 ident: bib18 article-title: Inflammatory and comorbid features of children admitted to a PICU for status asthmaticus publication-title: Pediatr Crit Care Med contributor: fullname: Fitzpatrick – volume: 323 start-page: 1061 year: 2020 end-page: 1069 ident: bib13 article-title: Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China publication-title: JAMA contributor: fullname: Zhang – volume: 20 start-page: 689 year: 2020 end-page: 696 ident: bib6 article-title: Clinical and epidemiological features of 36 children with coronavirus disease 2019 (COVID-19) in Zhejiang, China: an observational cohort study publication-title: Lancet Infect Dis contributor: fullname: Chen – volume: 395 start-page: 507 year: 2020 end-page: 513 ident: bib14 article-title: Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study publication-title: Lancet contributor: fullname: Han – volume: 140 start-page: 822 year: 2017 end-page: 827 ident: bib17 article-title: Urban residence, neighborhood poverty, race/ethnicity, and asthma morbidity among children on Medicaid publication-title: J Allergy Clin Immunol contributor: fullname: Peng – volume: 342 start-page: 1301 year: 2000 end-page: 1308 ident: bib9 article-title: Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome publication-title: N Engl J Med contributor: fullname: Thompson – volume: 395 start-page: 497 year: 2020 end-page: 506 ident: bib1 article-title: Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China publication-title: Lancet contributor: fullname: Hu – volume: 28 start-page: 505 year: 2009 end-page: 532 ident: bib15 article-title: Life course perspectives on the links between poverty and obesity during the transition to young adulthood publication-title: Popul Res Policy Rev contributor: fullname: Gordon-Larsen – volume: 323 start-page: 1574 year: 2020 end-page: 1581 ident: bib23 article-title: Characteristics and outcomes of 21 critically ill patients with COVID-19 in Washington State publication-title: JAMA contributor: fullname: Klaff – volume: 17 start-page: 204 year: 2013 ident: 10.1016/j.jpeds.2020.05.006_bib11 article-title: Diagnosis, evaluation, and management of acute kidney injury: a KDIGO summary (Part 1) publication-title: Crit Care doi: 10.1186/cc11454 contributor: fullname: Kellum – volume: 140 start-page: 822 year: 2017 ident: 10.1016/j.jpeds.2020.05.006_bib17 article-title: Urban residence, neighborhood poverty, race/ethnicity, and asthma morbidity among children on Medicaid publication-title: J Allergy Clin Immunol doi: 10.1016/j.jaci.2017.01.036 contributor: fullname: Keet – volume: 19 start-page: e585 year: 2018 ident: 10.1016/j.jpeds.2020.05.006_bib18 article-title: Inflammatory and comorbid features of children admitted to a PICU for status asthmaticus publication-title: Pediatr Crit Care Med doi: 10.1097/PCC.0000000000001695 contributor: fullname: Grunwell – volume: 323 start-page: 1574 year: 2020 ident: 10.1016/j.jpeds.2020.05.006_bib23 article-title: Characteristics and outcomes of 21 critically ill patients with COVID-19 in Washington State publication-title: JAMA doi: 10.1001/jama.2020.4326 contributor: fullname: Arentz – volume: 342 start-page: 1301 year: 2000 ident: 10.1016/j.jpeds.2020.05.006_bib9 article-title: Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome publication-title: N Engl J Med doi: 10.1056/NEJM200005043421801 contributor: fullname: Brower – volume: 323 start-page: 1061 year: 2020 ident: 10.1016/j.jpeds.2020.05.006_bib13 article-title: Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China publication-title: JAMA doi: 10.1001/jama.2020.1585 contributor: fullname: Wang – volume: 395 start-page: 507 year: 2020 ident: 10.1016/j.jpeds.2020.05.006_bib14 article-title: Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study publication-title: Lancet doi: 10.1016/S0140-6736(20)30211-7 contributor: fullname: Chen – volume: 323 start-page: 1574 year: 2020 ident: 10.1016/j.jpeds.2020.05.006_bib22 article-title: Baseline characteristics and outcomes of 1591 patients infected with SARS-CoV-2 admitted to ICUs of the Lombardy Region, Italy publication-title: JAMA doi: 10.1001/jama.2020.5394 contributor: fullname: Grasselli – volume: 144 start-page: e20190748 year: 2019 ident: 10.1016/j.jpeds.2020.05.006_bib19 article-title: Neighborhood poverty and pediatric intensive care use publication-title: Pediatrics doi: 10.1542/peds.2019-0748 contributor: fullname: Andrist – volume: 145 start-page: e20200702 year: 2020 ident: 10.1016/j.jpeds.2020.05.006_bib5 article-title: Epidemiological characteristics of 2143 pediatric patients with 2019 coronavirus disease in China publication-title: Pediatrics doi: 10.1542/peds.2020-0702 contributor: fullname: Dong – volume: 8 start-page: 475 year: 2020 ident: 10.1016/j.jpeds.2020.05.006_bib12 article-title: Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study publication-title: Lancet Respir Med doi: 10.1016/S2213-2600(20)30079-5 contributor: fullname: Yang – volume: 307 start-page: 2526 year: 2012 ident: 10.1016/j.jpeds.2020.05.006_bib8 article-title: Acute respiratory distress syndrome: the Berlin definition publication-title: JAMA contributor: fullname: Ranieri – volume: 395 start-page: 497 year: 2020 ident: 10.1016/j.jpeds.2020.05.006_bib1 article-title: Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China publication-title: Lancet doi: 10.1016/S0140-6736(20)30183-5 contributor: fullname: Huang – volume: 28 start-page: 505 year: 2009 ident: 10.1016/j.jpeds.2020.05.006_bib15 article-title: Life course perspectives on the links between poverty and obesity during the transition to young adulthood publication-title: Popul Res Policy Rev doi: 10.1007/s11113-008-9115-4 contributor: fullname: Lee – volume: 382 start-page: 2012 year: 2020 ident: 10.1016/j.jpeds.2020.05.006_bib24 article-title: Covid-19 in critically ill patients in the Seattle region—case series publication-title: N Engl J Med doi: 10.1056/NEJMoa2004500 contributor: fullname: Bhatraju – volume: 382 start-page: 1370 year: 2020 ident: 10.1016/j.jpeds.2020.05.006_bib4 article-title: Detection of 2019-nCoV in children in early January 2020 in Wuhan, China publication-title: N Engl J Med doi: 10.1056/NEJMc2003717 contributor: fullname: Liu – start-page: e200994 year: 2020 ident: 10.1016/j.jpeds.2020.05.006_bib20 article-title: Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China publication-title: JAMA Intern Med contributor: fullname: Wu – volume: 21 start-page: e52 year: 2020 ident: 10.1016/j.jpeds.2020.05.006_bib10 article-title: Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children publication-title: Pediatr Crit Care Med doi: 10.1097/PCC.0000000000002198 contributor: fullname: Weiss – volume: 20 start-page: 689 year: 2020 ident: 10.1016/j.jpeds.2020.05.006_bib6 article-title: Clinical and epidemiological features of 36 children with coronavirus disease 2019 (COVID-19) in Zhejiang, China: an observational cohort study publication-title: Lancet Infect Dis doi: 10.1016/S1473-3099(20)30198-5 contributor: fullname: Qiu – volume: 109 start-page: 40 year: 2002 ident: 10.1016/j.jpeds.2020.05.006_bib16 article-title: Social factors associated with prolonged hospitalization among diabetic children publication-title: Pediatrics doi: 10.1542/peds.109.1.40 contributor: fullname: Keenan – volume: 382 start-page: 1708 year: 2020 ident: 10.1016/j.jpeds.2020.05.006_bib2 article-title: Clinical characteristics of coronavirus disease 2019 in China publication-title: N Engl J Med doi: 10.1056/NEJMoa2002032 contributor: fullname: Guan – start-page: e201346 year: 2020 ident: 10.1016/j.jpeds.2020.05.006_bib7 article-title: Screening and severity of coronavirus disease 2019 (COVID-19) in children in Madrid, Spain publication-title: JAMA Pediatr contributor: fullname: Tagarro – volume: 382 start-page: 1663 year: 2020 ident: 10.1016/j.jpeds.2020.05.006_bib3 article-title: SARS-CoV-2 infection in children publication-title: N Engl J Med doi: 10.1056/NEJMc2005073 contributor: fullname: Lu |
SSID | ssj0009400 |
Score | 2.7170167 |
Snippet | To describe the clinical profiles and risk factors for critical illness in hospitalized children and adolescents with coronavirus disease 2019 (COVID-19).... |
SourceID | pubmedcentral crossref pubmed elsevier |
SourceType | Open Access Repository Aggregation Database Index Database Publisher |
StartPage | 14 |
SubjectTerms | Adenosine Monophosphate - analogs & derivatives Adenosine Monophosphate - therapeutic use Adolescent Alanine - analogs & derivatives Alanine - therapeutic use Antiviral Agents - therapeutic use Asthma - epidemiology Betacoronavirus Blood Urea Nitrogen C-Reactive Protein - analysis Child Child, Preschool children Coronavirus Infections - blood Coronavirus Infections - drug therapy Coronavirus Infections - epidemiology COVID-19 Creatinine - blood critical care Critical Illness Dyspnea - virology Female Hospitalization Hospitals, Pediatric Humans Infant Infant, Newborn Intensive Care Units, Pediatric - statistics & numerical data Male Natriuretic Peptide, Brain - blood New York City - epidemiology Original Pandemics Pediatric Obesity - epidemiology Platelet Count Pneumonia, Viral - blood Pneumonia, Viral - drug therapy Pneumonia, Viral - epidemiology Procalcitonin - blood Respiration, Artificial - statistics & numerical data Retrospective Studies SARS CoV-2 Sepsis - epidemiology Shock, Septic - epidemiology Tertiary Care Centers Young Adult |
Title | Clinical Characteristics and Outcomes of Hospitalized and Critically Ill Children and Adolescents with Coronavirus Disease 2019 at a Tertiary Care Medical Center in New York City |
URI | https://dx.doi.org/10.1016/j.jpeds.2020.05.006 https://www.ncbi.nlm.nih.gov/pubmed/32407719 https://pubmed.ncbi.nlm.nih.gov/PMC7212947 |
Volume | 223 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1LT9wwELYQlapeqr67paA59NiUZGOv4-MqBS2toBeQuEV-qkGrsFqyleiBH8UvZMZJlubSSj0mthU7M57xY-b7GPvkNDpZoV2ST1ORcOeKRDtlE-nRIPuAS5J44HZ6Nltc8G-X4nKHlUMuDIVV9ra_s-nRWvdvDvu_ebiqa8rxRdfGcTKTzhYxh4uLlFgMvtw9hnkQ8fcWMRxrD8hDMcbrauUdYXZP0wjfSbRH__BO48jJP1zR8Qv2vF9Dwrzr5ku245tX7Olpf0v-mt33YJ9LKMdwzKAbBz82LQ7W38B1gIE1pP7tXSwcmA-Wt3CypPZdqncsmz-CPwEd30JJ6Af6V73e3MDX7qIH0NMr0C1oOKeIbb2-BUpxgv5CCOg02a-hbgDNKxBgFJS4EXjDLo6PzstF0nMzJJYL1SbWUwaI5DYXhbFOC547G1TmjFQhk6gCsgg2C0JxH3Cmh44ky1tpTTo1On_Ldpvrxr9nYJThOTc5d1hZOWtmwRdGhhkvstwaMWGfB5lUqw6Coxpi066qKMKKRFilokIRTthskFs10qQKncTfG77rhLv9CoEVSpmpCZMjsW8rEDb3uKSpf0aMbtxYTxWXH_63M3vsGT11oYYf2W673vh9XP605iDq9wF7Mj_5vjh7AJSvCPg |
link.rule.ids | 230,314,780,784,885,4502,24116,27924,27925,45585,45679 |
linkProvider | Elsevier |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lb9swDBaKDth2KfZu9uh42HFe41iKrGPhrUi3prukQG-CnpiLwA1Sp0B32I_aLxzpRzpfVmBXU4JlkyIpivzI2Adv0MgK45NsMhYJ9z5PjFcukQEVcojokjQBt_nZdHbOv16Iix1W9LUwlFbZ6f5Wpzfaunty2P3Nw1VZUo0vmjaOm5lkNqcargdcoPeLQv3p112eB3X-3kKG4_AeeqhJ8rpcBU-g3ZNxg99JfY_uMU_D1Mm_bNHxE7bXOZFw1K7zKdsJ1TP2cN5dkz9nvzu0zyUUQzxmMJWH75savzZcw1WEvm1I-TP4hti3PljewsmS5re13g3t6A79CSh-CwXBH5ibcr25hs_tTQ-gqVdgajCwoJRts74FqnGC7kYIKJwc1lBWgPoVCDEKCjwJvGDnx18WxSzpmjMkjgtVJy5QCYjkLhO5dd4InnkXVeqtVDGVKAMyjy6NQvEQcavHtktWcNLZ8cSa7CXbra6qsM_AKsszbjPucbDyzk5jyK2MU56nmbNixD72PNGrFoND98lpl7phoSYW6rHQyMIRm_Z80wNR0mgl_j3xVcvc7VsIrVDKVI2YHLB9O4DAuYeUqvzRgHTjyXqiuHz9v4t5zx7NFvNTfXpy9u0Ne0yUNu_wLdut15vwDn2h2h40sv4HsnAKlQ |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Clinical+Characteristics+and+Outcomes+of+Hospitalized+and+Critically+Ill+Children+and+Adolescents+with+Coronavirus+Disease+2019+at+a+Tertiary+Care+Medical+Center+in+New+York+City&rft.jtitle=The+Journal+of+pediatrics&rft.au=Chao%2C+Jerry+Y.&rft.au=Derespina%2C+Kim+R.&rft.au=Herold%2C+Betsy+C.&rft.au=Goldman%2C+David+L.&rft.date=2020-08-01&rft.issn=0022-3476&rft.volume=223&rft.spage=14&rft.epage=19.e2&rft_id=info:doi/10.1016%2Fj.jpeds.2020.05.006&rft.externalDBID=n%2Fa&rft.externalDocID=10_1016_j_jpeds_2020_05_006 |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0022-3476&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0022-3476&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0022-3476&client=summon |