Understanding the Renal Fibrotic Process in Leptospirosis

• Published in: International journal of molecular sciences Vol. 22; no. 19; p. 10779
• Main Authors: Prado, Luan, Barbosa, Angela
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 01.10.2021; MDPI
• Subjects: Bacteria; Communicable diseases; Cytokines; Extracellular matrix; Growth factors; Health aspects; Kidney diseases; Leptospirosis; Ligands; Mutation; Phosphorylation; Proteins; Review; Risk factors; Signal transduction

Leptospirosis is a neglected infectious disease caused by pathogenic species of the genus Leptospira. The acute disease is well-described, and, although it resembles other tropical diseases, it can be diagnosed through the use of serological and molecular methods. While the chronic renal disease, ca...