Extracellular Signal-Regulated Kinase Regulates RhoA Activation and Tumor Cell Plasticity by Inhibiting Guanine Exchange Factor H1 Activity

• Published in: Molecular and Cellular Biology Vol. 33; no. 22; pp. 4526 - 4537
• Main Authors: von Thun, Anne, Preisinger, Christian, Rath, Oliver, Schwarz, Juliane P., Ward, Chris, Monsefi, Naser, Rodríguez, Javier, Garcia-Munoz, Amaya, Birtwistle, Marc, Bienvenut, Willy, Anderson, Kurt I., Kolch, Walter, von Kriegsheim, Alex
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 01.11.2013; Taylor & Francis
• Subjects: Amino Acid Sequence; Animals; Cell Line, Tumor; Cell Movement; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases - metabolism; HEK293 Cells; Humans; Molecular Sequence Data; Mutation; Neoplasm Invasiveness - genetics; Neoplasm Invasiveness - pathology; Neoplasms - genetics; Neoplasms - metabolism; Neoplasms - pathology; Phosphorylation; Proto-Oncogene Proteins c-fos - metabolism; Rats; Rho Guanine Nucleotide Exchange Factors - chemistry; Rho Guanine Nucleotide Exchange Factors - genetics; Rho Guanine Nucleotide Exchange Factors - metabolism; rhoA GTP-Binding Protein - metabolism; RNA Interference; Signal Transduction

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