Early high volume lung lavage for acute severe smoke inhalation injury in dogs

• Published in: Molecular medicine reports Vol. 9; no. 3; pp. 863 - 871
• Main Authors: NIE, FACHUAN, SU, DONG, SHI, YING, CHEN, JINMEI, WANG, HAIHUI, QIN, WANXIANG, WANG, SUXIA, CHEN, YAOHUA
• Format: Journal Article
• Language: English
• Published: Greece D.A. Spandidos 01.03.2014; Spandidos Publications; Spandidos Publications UK Ltd
• Subjects: Acute Disease; Animals; Anti-Inflammatory Agents - therapeutic use; Bronchoalveolar Lavage Fluid; Carbon monoxide; Carboxyhemoglobin - analysis; Care and treatment; Causes of; Disease Models, Animal; Dogs; Experiments; Fluorocarbons - chemistry; Fluorocarbons - therapeutic use; Free Radicals - chemistry; Free Radicals - metabolism; Health aspects; Hemodynamics; Inflammation; Inhalation; inhalation injury; Laboratory animals; Lung diseases; lung lavage; Lungs; Male; Medical research; Metabolites; Mortality; Oxygen - blood; perfluorodecalin; pulmonary function; Pulmonary Gas Exchange; Respiration; Saline Solution, Hypertonic - therapeutic use; Sawdust; secondary inflammatory response; Sheep; Short term; Smoke; Smoke inhalation; Smoke inhalation injuries; Smoke Inhalation Injury - pathology; Smoke Inhalation Injury - therapy; Time Factors; Ventilation; Ventilators; China

The aim of the present study was to investigate the safety and short-term results of early high volume lung lavage in the treatment of acute severe smoke inhalation injuries in dogs. A high-volume normal saline complex solution lavage in the left lung was performed 1 h subsequent to bilateral pulmon...