The Image Biomarker Standardization Initiative: Standardized Quantitative Radiomics for High-Throughput Image-based Phenotyping

• Published in: Radiology Vol. 295; no. 2; pp. 328 - 338
• Main Authors: Zwanenburg, Alex, Vallières, Martin, Abdalah, Mahmoud A., Aerts, Hugo J. W. L., Andrearczyk, Vincent, Apte, Aditya, Ashrafinia, Saeed, Bakas, Spyridon, Beukinga, Roelof J., Boellaard, Ronald, Bogowicz, Marta, Boldrini, Luca, Buvat, Irène, Cook, Gary J. R., Davatzikos, Christos, Depeursinge, Adrien, Desseroit, Marie-Charlotte, Dinapoli, Nicola, Dinh, Cuong Viet, Echegaray, Sebastian, El Naqa, Issam, Fedorov, Andriy Y., Gatta, Roberto, Gillies, Robert J., Goh, Vicky, Götz, Michael, Guckenberger, Matthias, Ha, Sung Min, Hatt, Mathieu, Isensee, Fabian, Lambin, Philippe, Leger, Stefan, Leijenaar, Ralph T.H., Lenkowicz, Jacopo, Lippert, Fiona, Losnegård, Are, Maier-Hein, Klaus H., Morin, Olivier, Müller, Henning, Napel, Sandy, Nioche, Christophe, Orlhac, Fanny, Pati, Sarthak, Pfaehler, Elisabeth A.G., Rahmim, Arman, Rao, Arvind U.K., Scherer, Jonas, Siddique, Muhammad Musib, Sijtsema, Nanna M., Socarras Fernandez, Jairo, Spezi, Emiliano, Steenbakkers, Roel J.H.M., Tanadini-Lang, Stephanie, Thorwarth, Daniela, Troost, Esther G.C., Upadhaya, Taman, Valentini, Vincenzo, van Dijk, Lisanne V., van Griethuysen, Joost, van Velden, Floris H.P., Whybra, Philip, Richter, Christian, Löck, Steffen
• Format: Journal Article
• Language: English
• Published: United States Radiological Society of North America 01.05.2020
• Subjects: Bioengineering; Biomarkers - analysis; Calibration; Fluorodeoxyglucose F18; Humans; Image Processing, Computer-Assisted - standards; Imaging; Life Sciences; Lung Neoplasms - diagnostic imaging; Magnetic Resonance Imaging; Original Research; Phantoms, Imaging; Phenotype; Positron-Emission Tomography; Radiopharmaceuticals; Reproducibility of Results; Sarcoma - diagnostic imaging; Software; Tomography, X-Ray Computed

Background Radiomic features may quantify characteristics present in medical imaging. However, the lack of standardized definitions and validated reference values have hampered clinical use. Purpose To standardize a set of 174 radiomic features. Materials and Methods Radiomic features were assessed...