Antagonizing CD105 and androgen receptor to target stromal-epithelial interactions for clinical benefit - Smith, Bethany N.; Mishra, Rajeev; Billet, Sandrine; Placencio-Hickok, Veronica R.; Kim, Minhyung; Zhang, Le; Duong, Frank; Madhav, Anisha; Scher, Kevin; Moldawer, Nancy; Oppenheim, Amy; Angara, Bryan; et al. (Molecular therapy, 2023)
Keywords: Androgen Receptor Antagonists - therapeutic use; androgen receptor splice variants; Antibodies, Neutralizing - therapeutic use; cancer-associated fibroblasts; CD105; Drug Resistance, Neoplasm; endoglin; Endoglin - antagonists & inhibitors; Humans; Male; Neoplastic Cells, Circulating - metabolism; Original; PCa; Prostatic Neoplasms, Castration-Resistant - drug therapy; Prostatic Neoplasms, Castration-Resistant - metabolism; Protein Isoforms; Receptors, Androgen - genetics; Receptors, Androgen - metabolism; RNA-Binding Proteins; androgen receptor splice variants; cancer-associated fibroblasts; CD105; endoglin; PCa