Resting state functional connectivity changes after MR-guided focused ultrasound mediated blood-brain barrier opening in patients with Alzheimer's disease - Meng, Ying; MacIntosh, Bradley J.; Shirzadi, Zahra; Kiss, Alex; Bethune, Allison; Heyn, Chinthaka; Mithani, Karim; Hamani, Clement; Black, Sandra E.; Hynynen, Kullervo; Lipsman, Nir (NeuroImage (Orlando, Fla.), 2019)
Keywords: Aged; Alzheimer Disease - diagnostic imaging; Alzheimer Disease - physiopathology; Alzheimer's disease; Animal cognition; Blood-brain barrier; Blood-Brain Barrier - diagnostic imaging; Blood-Brain Barrier - physiopathology; Blood-brain barrier opening; Brain research; Central nervous system; Clinical Trials, Phase I as Topic; Cognitive ability; Connectome; Drug delivery; Female; Frontal lobe; Functional connectivity; Functional magnetic resonance imaging; Functional morphology; Humans; Magnetic Resonance Imaging; Male; Medical imaging; Middle Aged; MR-Guided focused ultrasound; Nerve Net - diagnostic imaging; Nerve Net - physiopathology; Neural networks; Neurodegenerative diseases; Neuroimaging; Neuromodulation; Parietal Lobe - diagnostic imaging; Parietal Lobe - physiopathology; Prefrontal Cortex - diagnostic imaging; Prefrontal Cortex - physiopathology; Resting state functional MRI; Studies; Time Factors; Ultrasonic imaging; Ultrasonography, Doppler, Transcranial; Ultrasound; Functional connectivity; GLUT1; Resting state functional MRI; BBB; Blood-brain barrier; FUS; MR-Guided focused ultrasound; Blood-brain barrier opening; MRgFUS