Update on Advances in Research on Idiosyncratic Drug-Induced Liver Injury

• Published in: Allergy, asthma & immunology research Vol. 8; no. 1; pp. 3 - 11
• Main Authors: Kim, Seung-Hyun, Naisbitt, Dean J.
• Format: Journal Article
• Language: English
• Published: Korea (South) The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 01.01.2016; 대한천식알레르기학회
• Subjects: Review; 내과학; Drug-induced liver injury; T-cell; biomarker; hapten; human leukocyte antigen; immune response

Drug-induced liver injury (DILI) is a major concern for public health, as well as for drug development in the pharmaceutical industry, since it can cause liver failure and lead to drug withdrawal from the market and black box warnings. Thus, it is important to identify biomarkers for early predictio...