Precision medicine: In vivo CAR therapy as a showcase for receptor-targeted vector platforms

Chimeric antigen receptor (CAR) T cells are a cancer immunotherapy of extremes. Unprecedentedly effective, but complex and costly to manufacture, they are not yet a therapeutic option for all who would benefit. This disparity has motivated worldwide efforts to simplify treatment. Among the proposed...

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Bibliographic Details
Published inMolecular therapy Vol. 30; no. 7; pp. 2401 - 2415
Main Authors Michels, Alexander, Ho, Naphang, Buchholz, Christian J.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 06.07.2022
American Society of Gene & Cell Therapy
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