Vibrio vulnificus detected in the spleen leads to fatal outcome in a mouse oral infection model

• Published in: FEMS microbiology letters Vol. 362; no. 7
• Main Authors: Kashimoto, Takashige, Iwasaki, Chiemi, Gojo, Masanori, Sugiyama, Hiroyuki, Yoshioka, Kazuki, Yamamoto, Yuji, Okamura, Masashi, Susa, Nobuyuki, Ueno, Shunji
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 01.04.2015
• Subjects: Animal models; Animals; Bacterial diseases; Bile; Bile ducts; Bile Ducts - surgery; Chronic infection; Disease Models, Animal; Hepatitis; Hepatitis - complications; Infections; Inoculum; Intestine; Intestines - microbiology; Liver; Liver - chemistry; Liver - microbiology; Liver - ultrastructure; Liver diseases; Mice; Microbiology; Mouth - microbiology; Oral infection; Pathogens; Risk analysis; Risk Factors; Sepsis; Septicemia; Spleen; Spleen - microbiology; Survival; Vibrio Infections - microbiology; Vibrio vulnificus; Vibrio vulnificus - growth & development; Vibrio vulnificus - pathogenicity; Waterborne diseases; risk factor; liver diseases; sepsis; Vibrio vulnificus

Vibrio vulnificus causes rapid disseminating septicemia by oral infection in infected individuals who have an underlying disease, especially chronic liver diseases. Although the elucidation of specific risk factors for V. vulnificus infection in patients with liver diseases is of urgent importance,...