Reactive Oxygen Species (ROS), Intimal Thickening, and Subclinical Atherosclerotic Disease

• Published in: Frontiers in cardiovascular medicine Vol. 6; p. 89
• Main Authors: Burtenshaw, Denise, Kitching, Michael, Redmond, Eileen M., Megson, Ian L., Cahill, Paul A.
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 02.08.2019
• Subjects: adventitial cells; Cardiovascular Medicine; endothelial cells; NAPDH oxidase; NOX; smooth muscle (physiology); stem cells; stem cells; arteriosclerosis; endothelial cells; NAPDH oxidase; NOX; intimal thickening; smooth muscle (physiology); adventitial cells

Arteriosclerosis causes significant morbidity and mortality worldwide. Central to this process is the development of subclinical non-atherosclerotic intimal lesions before the appearance of pathologic intimal thickening and advanced atherosclerotic plaques. Intimal thickening is associated with seve...