Neural correlates of pupil dilation during human fear learning

• Published in: NeuroImage (Orlando, Fla.) Vol. 147; pp. 186 - 197
• Main Authors: Leuchs, Laura, Schneider, Max, Czisch, Michael, Spoormaker, Victor I.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 15.02.2017; Elsevier Limited
• Subjects: Anxiety; Arousal; Baas; Brain mapping; Cognitive ability; Conditioned response; Conductance; Data processing; Dorsal anterior cingulate cortex; Electromyography; Emotions; Expectancy; Extinction behavior; Eye; Fear conditioning; Fear extinction; fMRI; Functional magnetic resonance imaging; Habituation; Learning; Light; Neuroimaging; Pain; Physiology; Post traumatic stress disorder; Pupillometry; Reflexes; Salience network; Skin; Startle response; Unconditioned stimulus; Fear extinction; Dorsal anterior cingulate cortex; fMRI; Salience network; Pupillometry; Fear conditioning

Fear conditioning and extinction are prevailing experimental and etiological models for normal and pathological anxiety. Pupil dilations in response to conditioned stimuli are increasingly used as a robust psychophysiological readout of fear learning, but their neural correlates remain unknown. We a...