Noninvasive Prediction of Elevated Wedge Pressure in Pulmonary Hypertension Patients Without Clear Signs of Left-Sided Heart Disease: External Validation of the OPTICS Risk Score

• Published in: Journal of the American Heart Association Vol. 9; no. 15; p. e015992
• Main Authors: Jansen, Samara M A, Huis In 't Veld, Anna E, Jacobs, Wouter, Grotjohan, Hans P, Waskowsky, Marc, van der Maten, Jan, van der Weerdt, Arno, Hoekstra, Romke, Overbeek, Maria J, Mollema, Sjoerd A, Tolen, Peter Hans C G, Hassan El Bouazzaoui, Lahssan H, Vriend, Joris W J, Roorda, J Milena M, de Nooijer, Ramon, van der Lee, Ivo, Voogel, Bart A J, Peels, Kathinka, Macken, Thomas, Aerts, Jacqueline M, Vonk Noordegraaf, Anton, Handoko, M Louis, de Man, Frances S, Bogaard, Harm Jan
• Format: Journal Article
• Language: English
• Published: England John Wiley and Sons Inc 04.08.2020; Wiley
• Subjects: Aged; diagnosis; Female; heart failure; Humans; Hypertension, Pulmonary - diagnosis; Hypertension, Pulmonary - physiopathology; Logistic Models; Male; Middle Aged; Original Research; prediction models; pulmonary vasculature; Pulmonary Wedge Pressure; Retrospective Studies; Risk Assessment - methods; Risk Factors; ROC Curve; validation study; Ventricular Dysfunction, Left - diagnosis; Ventricular Dysfunction, Left - physiopathology; heart failure; prediction models; diagnosis; validation study; pulmonary vasculature

Background Although most newly presenting patients with pulmonary hypertension (PH) have elevated pulmonary artery wedge pressure, identification of so-called postcapillary PH can be challenging. A noninvasive tool predicting elevated pulmonary artery wedge pressure in patients with incident PH may...