Aging, inflammation and the environment

• Published in: Experimental gerontology Vol. 105; pp. 10 - 18
• Main Authors: Bektas, Arsun, Schurman, Shepherd H., Sen, Ranjan, Ferrucci, Luigi
• Format: Journal Article
• Language: English
• Published: England Elsevier Inc 01.05.2018
• Subjects: Aged; Aging; Aging - physiology; Cognition; Environment; Frail Elderly - psychology; Humans; Inflammaging; Inflammation; Inflammation - physiopathology; Longitudinal Studies; Risk Factors; Aging; Environment; Inflammaging; Inflammation; Longitudinal studies

The aging process is driven by interrelated mechanisms that lead to the emergence of characteristic phenotypes that include changes in body composition, energy production and utilization imbalance, homeostatic dysregulation, and neurodegeneration and loss of neuroplasticity. Mainstream theories of a...