Chimeric lipoproteins for leptospirosis vaccine: immunogenicity and protective potential - Tapajóz, Rafael Carracena de Souza; Santos, Francisco Denis Souza; de Oliveira, Natasha Rodrigues; Maia, Mara Andrade Colares; Seixas Neto, Amilton Clair Pinto; Maiocchi, Laura de Vargas; Souza, Pedro Henrique Filgueiras Coelho; Oliveira, Thaís Larré; Dellagostin, Odir Antônio (Applied microbiology and biotechnology, 2024)
Keywords: Adjuvants; Adjuvants, Immunologic - administration & dosage; Aluminum; Aluminum hydroxide; Animals; Antibodies, Bacterial - blood; Antibodies, Bacterial - immunology; B-lymphocytes; Bacterial Outer Membrane Proteins - genetics; Bacterial Outer Membrane Proteins - immunology; Bacterial Vaccines - genetics; Bacterial Vaccines - immunology; Biomedical and Life Sciences; Biotechnological Products and Process Engineering; Biotechnology; Conserved sequence; Cricetinae; E coli; Epitopes; Epitopes, B-Lymphocyte - genetics; Epitopes, B-Lymphocyte - immunology; Epitopes, T-Lymphocyte - genetics; Epitopes, T-Lymphocyte - immunology; Escherichia coli; genes; genus; Hamsters; humoral immunity; Immune response; Immune response (humoral); Immune system; Immunity, Humoral; Immunization; Immunodominance; Immunogenicity; Immunogenicity, Vaccine; Immunoglobulin G; Immunoglobulin G - blood; Leptospira; Leptospira - genetics; Leptospira - immunology; Leptospira interrogans - genetics; Leptospira interrogans - immunology; Leptospirosis; Leptospirosis - immunology; Leptospirosis - prevention & control; Life Sciences; Lipoproteins; Lipoproteins - genetics; Lipoproteins - immunology; Lymphocytes B; Microbial Genetics and Genomics; Microbiology; Morbidity; mortality; Protein biosynthesis; Proteins; recombinant fusion proteins; Recombinant Fusion Proteins - genetics; Recombinant Fusion Proteins - immunology; Robust control; Spirochetes; Vaccination; Vaccines; virulence; Zoonoses; Adjuvants; vaccine; Chimeric protein; Recombinant subunit vaccine; Recombinant inactivated; Recombinant bacterin; Recombinant inactivated E. coli vaccine; Leptospira