Computer-controlled infusion of ORG 21465, a water soluble steroid i.v. anaesthetic agent, into human volunteers - Sneyd, J R; Wright, P M; Harris, D; Taylor, P A; Vijn, P C; Cross, M; Dale, H; Voortman, G; Boen, P (British journal of anaesthesia : BJA, 1997)
Keywords: Adult; Anesthesia, Intravenous; Anesthetics, Intravenous - administration & dosage; Anesthetics, Intravenous - pharmacokinetics; Anesthetics, Intravenous - pharmacology; Anesthetics. Neuromuscular blocking agents; Biological and medical sciences; Drug Therapy, Computer-Assisted; Electroencephalography - drug effects; Electromyography - drug effects; Humans; Infusions, Intravenous; Male; Medical sciences; Neuropharmacology; Pharmacology. Drug treatments; Pregnanediones - pharmacokinetics; Pregnanediones - pharmacology; Solubility; Water; Human; Steroid; Intravenous administration; General anesthetic; Activity concentration relation; General anesthesia; Sedation; Normal; Pharmacokinetics; Computer aid; Monitoring