Identification of Immunoglobulin E-Binding Proteins of the Xerophilic Fungus Aspergillus penicillioides Crude Mycelial Mat Extract and Serological Reactivity Assessment in Subjects with Different Allergen Reactivity Profiles

• Published in: International archives of allergy and immunology Vol. 175; no. 3; p. 147
• Main Authors: González De León, Joenice, González Méndez, Ricardo, Cadilla, Carmen L, Rivera-Mariani, Félix E, Bolaños-Rosero, Benjamín
• Format: Journal Article
• Language: English
• Published: Switzerland 01.03.2018
• Subjects: Allergens - immunology; Antibodies, Fungal - immunology; Antigens, Fungal - immunology; Aspergillus - immunology; Blotting, Western; Carrier Proteins; Case-Control Studies; Enzyme-Linked Immunosorbent Assay; Humans; Immunoglobulin E - immunology; Mass Spectrometry; Pilot Projects; Principal Component Analysis; Aspergillus penicillioides; Allergy; Xerophilic fungi; Immunoglobulin E-binding proteins; Serologic reactivity

Aspergillus penicillioides is a very common indoor xerophilic fungus and potential causative agent of respiratory conditions. Although people are constantly exposed to A. penicillioides, no proteins with allergenic potential have been described. Therefore, we aim to confirm allergic sensitization to...