Effects of aprepitant on cytochrome P450 3A4 activity using midazolam as a probe - Majumdar, Anup K; McCrea, Jacqueline B; Panebianco, Deborah L; Hesney, Michael; Dru, James; Constanzer, Marvin; Goldberg, Michael R; Murphy, Gail; Gottesdiener, Keith M; Lines, Christopher R; Petty, Kevin J; Blum, Robert A (Clinical pharmacology and therapeutics, 2003)
Keywords: Adult; Anti-Anxiety Agents - pharmacokinetics; Antiemetics - pharmacology; Aprepitant; Area Under Curve; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Drug Interactions; Half-Life; Humans; Male; Midazolam - pharmacokinetics; Morpholines - pharmacology; Neurokinin-1 Receptor Antagonists