Dendritic cells in Th2 immune responses and allergic sensitization

• Published in: Immunology and cell biology Vol. 98; no. 10; p. 807
• Main Authors: Lamiable, Olivier, Mayer, Johannes U, Munoz-Erazo, Luis, Ronchese, Franca
• Format: Journal Article
• Language: English
• Published: United States 01.11.2020
• Subjects: allergy; conventional dendritic cells; Adaptive immunity; antigen presentation; T-helper 2 cells

Allergic responses are characterized by the activation of a specific subset of effector CD4 T cells, the T-helper type 2 (Th2) cells, that respond to harmless environmental antigens causing inflammation and pathology. Th2 cells are also found in the context of parasite infections, where they can med...