Impact of early statin therapy in patients with ischemic stroke or transient ischemic attack

• Published in: Acta neurologica Scandinavica Vol. 129; no. 1; pp. 41 - 48
• Main Authors: Chen, P.-S., Cheng, C.-L., Kao Yang, Y.-H., Yeh, P.-S., Li, Y.-H.
• Format: Journal Article
• Language: English
• Published: Denmark Blackwell Publishing Ltd 01.01.2014; Hindawi Limited
• Subjects: Acute Coronary Syndrome - epidemiology; Acute Coronary Syndrome - etiology; Aged; Anticholesteremic Agents - administration & dosage; Anticholesteremic Agents - adverse effects; Anticholesteremic Agents - therapeutic use; Brain Ischemia - drug therapy; Cerebral Hemorrhage - chemically induced; Cerebral Hemorrhage - epidemiology; Cholesterol - blood; Comorbidity; Drug Administration Schedule; Female; Follow-Up Studies; Genetic Predisposition to Disease; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage; Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects; Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use; Incidence; Inpatients; Ischemic Attack, Transient - drug therapy; ischemic stroke; Male; Middle Aged; Outpatients; Polypharmacy; statin; Taiwan - epidemiology; transient ischemic attack; Treatment Outcome; Taiwan; statin; transient ischemic attack; ischemic stroke

Background Statin therapy has demonstrated benefits in ischemic stroke patients. However, little is known about whether the timing of statin initiation affects clinical outcomes. The possible association of statin use and cerebral hemorrhage is also a concern for early statin therapy after stroke. T...