Acute Change in Vascular Tone Alters Intima-Media Thickness

• Published in: Hypertension (Dallas, Tex. 1979) Vol. 58; no. 2; pp. 240 - 246
• Main Authors: Thijssen, Dick H.J., Scholten, Ralph R., van den Munckhof, Inge C.L., Benda, Nathalie, Green, Daniel J., Hopman, Maria T.E.
• Format: Journal Article
• Language: English
• Published: Hagerstown, MD American Heart Association, Inc 01.08.2011; Lippincott Williams & Wilkins
• Subjects: Adult; Aged; Arterial hypertension. Arterial hypotension; Biological and medical sciences; Blood and lymphatic vessels; Blood vessels and receptors; Cardiology. Vascular system; Carotid Arteries - diagnostic imaging; Carotid Arteries - drug effects; Femoral Artery - diagnostic imaging; Femoral Artery - drug effects; Fundamental and applied biological sciences. Psychology; Humans; Male; Medical sciences; Middle Aged; Nitroglycerin - pharmacology; Tunica Intima - diagnostic imaging; Tunica Intima - drug effects; Tunica Media - diagnostic imaging; Tunica Media - drug effects; Ultrasonography; Vasodilation - drug effects; Vasodilator Agents - pharmacology; Vertebrates: cardiovascular system; Vascular disease; Hypertension; Senescence; Atherosclerosis; Risk factor; wall characteristics; Cardiovascular disease; aging; arterial remodeling; cardiovascular risk

Atherosclerosis is a lifelong process involving artery wall thickening. Increased wall thickness has been widely adopted as a preclinical surrogate marker of atherosclerosis. A prerequisite for such a surrogate marker is that it is a structural characteristic of the vessel wall that is not subject t...