Cannabinoid pharmacology in cancer research: A new hope for cancer patients?

• Published in: European journal of pharmacology Vol. 775; pp. 1 - 14
• Main Authors: Javid, Farideh A., Phillips, Roger M., Afshinjavid, S., Verde, Roberta, Ligresti, Alessia
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 15.03.2016
• Subjects: Animals; Antineoplastic Agents - therapeutic use; Cancer; Cannabinoid receptors; Cannabinoids; Cannabinoids - therapeutic use; Humans; Neoplasms - drug therapy; FAAH; PR; Gi/o; TIMP-1; TRB3; AKt; Cdk; PRLr; HU-210; JWH-133; NF-κB; PI3K; TRPVA1; AM251; CB1IR; mTOR; TrK A; Src gene; Th1; AEA; PSA; Th2; Cannabinoid receptors; ABCC1; AC; PKA; JWH-015; NGF; ER; AR; MMP-2; PyMT; 2-AG; ROS; AMPK; SC58236; MMP-9; ERK; PCNA; RXRα; CBD; LPI; CXCR4; SB203580; EGFR; AM630; HIF-α; Cannabinoids; GBM; GTPγS; WIN 55,212–2; PD98059; COX2; MAGL; TRPM8; SR141716; ATF-4; PGE2; MRP1; ICAM; VEGF; siRNA; TRPV1; PPARs; FAK; CXCL12; Chk 1; Δ9-THC; LAK; RAF-1; HER2; Cancer

Cannabinoids have been used for many centuries to ease pain and in the past decade, the endocannabinoid system has been implicated in a number of pathophysiological conditions, such as mood and anxiety disorders, movement disorders such as Parkinson's and Huntington's disease, neuropathic...