Selection Effects May Explain Smoking-related Outcome Differences After Radical Cystectomy

• Published in: European urology focus Vol. 4; no. 3; pp. 395 - 398
• Main Authors: Froehner, Michael, Koch, Rainer, Hübler, Matthias, Heberling, Ulrike, Novotny, Vladimir, Zastrow, Stefan, Baretton, Gustavo B., Wirth, Manfred P.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.05.2018
• Subjects: Aged; Bladder cancer; Competing risks analysis; Cystectomy - methods; Disease-Free Survival; Female; Humans; Lung cancer; Male; Middle Aged; Mortality; Neoplasms, Second Primary - epidemiology; Neoplasms, Second Primary - mortality; Outcome Assessment (Health Care); Proportional hazards model; Radical cystectomy; Risk Factors; Second cancer; Smoking; Smoking - adverse effects; Urinary Bladder Neoplasms - epidemiology; Urinary Bladder Neoplasms - mortality; Urinary Bladder Neoplasms - surgery; Urologic neoplasms; Urology; Competing risks analysis; Second cancer; Lung cancer; Mortality; Urologic neoplasms; Bladder cancer; Radical cystectomy; Smoking; Proportional hazards model

The impact of smoking on mortality among patients with bladder cancer is subject to controversy. We investigated 1000 patients who consecutively underwent radical cystectomy between 1993 and 2013. Proportional hazards models for competing risks were used to study the combined effects of variables on...