Orbital frontal cortex functional connectivity during gain anticipation linking the rumination and non-suicidal self-injury in late adolescence

• Published in: Journal of affective disorders Vol. 350; pp. 673 - 680
• Main Authors: Lin, Lin, Liu, Yu, Qiu, Shaojie, Yang, Yanan, Yang, Yang, Tian, Mingyangjia, Wang, Song, Zhang, Jie, Bai, Xuejun, Xu, Zhansheng
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.04.2024
• Subjects: Adolescent; Biomarkers; Brain; Brain Mapping; Gain anticipation; Humans; Late adolescence; Magnetic Resonance Imaging; Non-suicidal self-injury; PPI; Prefrontal Cortex - diagnostic imaging; Psychiatric/Mental Health; Rumination; Self-Injurious Behavior - psychology; PPI; Late adolescence; Rumination; Non-suicidal self-injury; Gain anticipation

Non-suicidal self-injury (NSSI) is prevalent and especially among the adolescence population. It has been argued that abnormal brain activations in reward processing could be regarded as objective biomarkers in NSSI, but the evidence is mixed. This study aims to explore the reward processing mechani...