Parsing the heterogeneity of depression: An exploratory factor analysis across commonly used depression rating scales

• Published in: Journal of affective disorders Vol. 231; pp. 51 - 57
• Main Authors: Ballard, Elizabeth D., Yarrington, Julia S., Farmer, Cristan A., Lener, Marc S., Kadriu, Bashkim, Lally, Níall, Williams, Deonte, Machado-Vieira, Rodrigo, Niciu, Mark J., Park, Lawrence, Zarate, Carlos A.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 15.04.2018
• Subjects: Adult; Antidepressive Agents - therapeutic use; Bipolar Disorder - diagnosis; Bipolar Disorder - drug therapy; Bipolar Disorder - psychology; Clinical trials; Depression; Depressive Disorder, Major - diagnosis; Depressive Disorder, Major - drug therapy; Depressive Disorder, Major - psychology; Factor analysis; Factor Analysis, Statistical; Female; Humans; Ketamine; Ketamine - therapeutic use; Male; Middle Aged; Psychiatric Status Rating Scales - statistics & numerical data; Psychometrics; Psychotropic Drugs - therapeutic use; Symptom Assessment - methods; Symptom Assessment - statistics & numerical data; Young Adult; Clinical trials; Depression; Psychometrics; Ketamine; Factor analysis

Due to the heterogeneity of depressive symptoms—which can include depressed mood, anhedonia, negative cognitive biases, and altered activity levels—researchers often use a combination of depression rating scales to assess symptoms. This study sought to identify unidimensional constructs measured acr...