Efficacy and Safety of Low-field Synchronized Transcranial Magnetic Stimulation (sTMS) for Treatment of Major Depression

• Published in: Brain stimulation Vol. 8; no. 4; pp. 787 - 794
• Main Authors: Leuchter, Andrew F., Cook, Ian A., Feifel, David, Goethe, John W., Husain, Mustafa, Carpenter, Linda L., Thase, Michael E., Krystal, Andrew D., Philip, Noah S., Bhati, Mahendra T., Burke, William J., Howland, Robert H., Sheline, Yvette I., Aaronson, Scott T., Iosifescu, Dan V., O'Reardon, John P., Gilmer, William S., Jain, Rakesh, Burgoyne, Karl S., Phillips, Bill, Manberg, Paul J., Massaro, Joseph, Hunter, Aimee M., Lisanby, Sarah H., George, Mark S.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.07.2015
• Subjects: Alpha oscillations; Clinical treatment trial; Depressive Disorder, Major - therapy; Double-Blind Method; Electroencephalogram (EEG); Female; Humans; Individual Alpha Frequency (IAF); Low-intensity magnetic field; Major Depressive Disorder; Male; Middle Aged; Neurology; Neuromodulation; Oscillatory synchrony; Psychiatric Status Rating Scales; Static magnet; Synchronized Transcranial Magnetic Stimulation (sTMS); Transcranial Magnetic Stimulation - adverse effects; Transcranial Magnetic Stimulation - methods; Treatment Outcome; Static magnet; Clinical treatment trial; Individual Alpha Frequency (IAF); Electroencephalogram (EEG); Synchronized Transcranial Magnetic Stimulation (sTMS); Neuromodulation; Alpha oscillations; Low-intensity magnetic field; Oscillatory synchrony; Major Depressive Disorder

Transcranial Magnetic Stimulation (TMS) customarily uses high-field electromagnets to achieve therapeutic efficacy in Major Depressive Disorder (MDD). Low-field magnetic stimulation also may be useful for treatment of MDD, with fewer treatment-emergent adverse events. To examine efficacy, safety, an...