Large-scale comparative metagenomics of Blastocystis, a common member of the human gut microbiome

• Published in: The ISME Journal Vol. 11; no. 12; pp. 2848 - 2863
• Main Authors: Beghini, Francesco, Pasolli, Edoardo, Truong, Tin Duy, Putignani, Lorenza, Cacciò, Simone M, Segata, Nicola
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.12.2017; Oxford University Press; Nature Publishing Group
• Subjects: 45; 45/23; 631/208/457; 631/326/107; Bacteria; Biomedical and Life Sciences; Body mass index; Body size; Colonization; Colorectal cancer; Colorectal carcinoma; Crohn's disease; Digestive system; Dysbacteriosis; Ecological monitoring; Ecology; Epidemiology; Evolutionary Biology; Genomes; Genomic analysis; Intestinal microflora; Life Sciences; Microbial Ecology; Microbial Genetics and Genomics; Microbiology; Microbiota; Microorganisms; Original; original-article; Parasites

The influence of unicellular eukaryotic microorganisms on human gut health and disease is still largely unexplored. Blastocystis spp. commonly colonize the gut, but its clinical significance and ecological role are currently unsettled. We have developed a high-sensitivity bioinformatic pipeline to d...