An opinion on the 'delayed spikes' in human motoneurons
This is a note challenging the claim by Kudina and Andreeva’s recent publication in Experimental Brain Research. In that publication, Kudina and Andreeva (Exp Brain Res 239:719–730, 2021) put forward a new idea about discovering two spiking modes in human motoneurons. We suggest that what they have...
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Published in | Experimental brain research Vol. 240; no. 1; pp. 1 - 3 |
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Main Author | |
Format | Journal Article |
Language | English |
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Berlin/Heidelberg
Springer Berlin Heidelberg
2022
Springer Springer Nature B.V |
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Abstract | This is a note challenging the claim by Kudina and Andreeva’s recent publication in Experimental Brain Research. In that publication, Kudina and Andreeva (Exp Brain Res 239:719–730, 2021) put forward a new idea about discovering two spiking modes in human motoneurons. We suggest that what they have shown in their publication maybe is the motor unit firing indicating the end of a net synaptic potential. We reason this challenge from our previous publication in the same journal. In that publication, we have shown that the "second spiking mode" after the H-reflex was a return to the regular prestimulus discharge rate. |
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AbstractList | This is a note challenging the claim by Kudina and Andreeva's recent publication in Experimental Brain Research. In that publication, Kudina and Andreeva (Exp Brain Res 239:719-730, 2021) put forward a new idea about discovering two spiking modes in human motoneurons. We suggest that what they have shown in their publication maybe is the motor unit firing indicating the end of a net synaptic potential. We reason this challenge from our previous publication in the same journal. In that publication, we have shown that the "second spiking mode" after the H-reflex was a return to the regular prestimulus discharge rate. This is a note challenging the claim by Kudina and Andreeva’s recent publication in Experimental Brain Research. In that publication, Kudina and Andreeva (Exp Brain Res 239:719–730, 2021) put forward a new idea about discovering two spiking modes in human motoneurons. We suggest that what they have shown in their publication maybe is the motor unit firing indicating the end of a net synaptic potential. We reason this challenge from our previous publication in the same journal. In that publication, we have shown that the "second spiking mode" after the H-reflex was a return to the regular prestimulus discharge rate. |
Audience | Academic |
Author | Türker, Kemal S. |
Author_xml | – sequence: 1 givenname: Kemal S. orcidid: 0000-0001-9962-075X surname: Türker fullname: Türker, Kemal S. email: turker.77@gmail.com organization: Faculty of Dentistry, Istanbul Gelisim University |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/35028693$$D View this record in MEDLINE/PubMed |
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Cites_doi | 10.1007/s00221-020-05998-2 10.1152/jn.1992.68.3.964 10.1113/jphysiol.1966.sp008097 10.1093/brain/awn050 10.1152/jn.1999.82.2.829 10.1371/journal.pone.0225535 10.1007/s00221-008-1536-0 10.1016/j.tins.2005.05.007 10.1016/0006-8993(73)90278-3 10.1113/jphysiol.2003.044982 10.1007/s00221-011-2779-8 |
ContentType | Journal Article |
Copyright | The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2021 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature. COPYRIGHT 2022 Springer The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2021. |
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References | Granit, Kernell, Lamarre (CR2) 1966; 187 Türker, Powers (CR10) 2003; 551 Kudina, Andreeva (CR3) 2021; 239 Schwindt, Calvin (CR8) 1973; 59 Powers, Robinson, Konodi, Binder (CR6) 1992; 68 Özyurt, Haavik, Nedergaard, Topkara, Şenocak, Göztepe, Niazi, Türker (CR5) 2019; 14 Binboğa, Prasartwuth, Pehlivan, Türker (CR1) 2011; 213 Türker, Powers (CR11) 2005; 28 Prasartwuth, Binboğa, Türker (CR7) 2008; 191 Norton, Bennett, Knash, Murray, Gorassini (CR4) 2008; 131 Türker, Powers (CR9) 1999; 82 RK Powers (6290_CR6) 1992; 68 E Binboğa (6290_CR1) 2011; 213 MG Özyurt (6290_CR5) 2019; 14 KS Türker (6290_CR9) 1999; 82 R Granit (6290_CR2) 1966; 187 JA Norton (6290_CR4) 2008; 131 PC Schwindt (6290_CR8) 1973; 59 LP Kudina (6290_CR3) 2021; 239 KS Türker (6290_CR11) 2005; 28 O Prasartwuth (6290_CR7) 2008; 191 KS Türker (6290_CR10) 2003; 551 |
References_xml | – volume: 239 start-page: 719 issue: 3 year: 2021 end-page: 730 ident: CR3 article-title: Evidence of two modes of spiking evoked in human firing motoneurones by Ia afferent electrical stimulation publication-title: Exp Brain Res doi: 10.1007/s00221-020-05998-2 contributor: fullname: Andreeva – volume: 68 start-page: 964 issue: 3 year: 1992 end-page: 968 ident: CR6 article-title: Effective synaptic current can be estimated from measurements of neuronal discharge publication-title: J Neurophysiol doi: 10.1152/jn.1992.68.3.964 contributor: fullname: Binder – volume: 187 start-page: 379 issue: 2 year: 1966 end-page: 399 ident: CR2 article-title: Algebraical summation in synaptic activation of motoneurones firing within the ‘primary range’ to injected currents publication-title: J Physiol doi: 10.1113/jphysiol.1966.sp008097 contributor: fullname: Lamarre – volume: 131 start-page: 1478 issue: Pt 6 year: 2008 end-page: 1491 ident: CR4 article-title: Changes in sensory-evoked synaptic activation of motoneurons after spinal cord injury in man publication-title: Brain doi: 10.1093/brain/awn050 contributor: fullname: Gorassini – volume: 82 start-page: 829 issue: 2 year: 1999 end-page: 840 ident: CR9 article-title: Effects of large excitatory and inhibitory inputs on motoneuron discharge rate and probability publication-title: J Neurophysiol doi: 10.1152/jn.1999.82.2.829 contributor: fullname: Powers – volume: 14 start-page: e0225535 issue: 12 year: 2019 ident: CR5 article-title: Transcranial magnetic stimulation-induced early silent period and rebound activity re-examined publication-title: PLoS ONE doi: 10.1371/journal.pone.0225535 contributor: fullname: Türker – volume: 191 start-page: 465 issue: 4 year: 2008 end-page: 472 ident: CR7 article-title: A study of synaptic connection between low threshold afferent fibres in common peroneal nerve and motoneurones in human tibialis anterior publication-title: Exp Brain Res doi: 10.1007/s00221-008-1536-0 contributor: fullname: Türker – volume: 28 start-page: 379 issue: 7 year: 2005 end-page: 386 ident: CR11 article-title: Black box revisited: a technique for estimating postsynaptic potentials in neurons publication-title: Trends Neurosci doi: 10.1016/j.tins.2005.05.007 contributor: fullname: Powers – volume: 59 start-page: 389 year: 1973 end-page: 394 ident: CR8 article-title: Equivalence of synaptic and injected current in determining the membrane potential trajectory during motoneuron rhythmic firing publication-title: Brain Res doi: 10.1016/0006-8993(73)90278-3 contributor: fullname: Calvin – volume: 551 start-page: 419 issue: Pt 2 year: 2003 end-page: 431 ident: CR10 article-title: Estimation of postsynaptic potentials in rat hypoglossal motoneurones: insights for human work publication-title: J Physiol doi: 10.1113/jphysiol.2003.044982 contributor: fullname: Powers – volume: 213 start-page: 73 issue: 1 year: 2011 end-page: 86 ident: CR1 article-title: Responses of human soleus motor units to low-threshold stimulation of the tibial nerve publication-title: Exp Brain Res doi: 10.1007/s00221-011-2779-8 contributor: fullname: Türker – volume: 213 start-page: 73 issue: 1 year: 2011 ident: 6290_CR1 publication-title: Exp Brain Res doi: 10.1007/s00221-011-2779-8 contributor: fullname: E Binboğa – volume: 131 start-page: 1478 issue: Pt 6 year: 2008 ident: 6290_CR4 publication-title: Brain doi: 10.1093/brain/awn050 contributor: fullname: JA Norton – volume: 191 start-page: 465 issue: 4 year: 2008 ident: 6290_CR7 publication-title: Exp Brain Res doi: 10.1007/s00221-008-1536-0 contributor: fullname: O Prasartwuth – volume: 82 start-page: 829 issue: 2 year: 1999 ident: 6290_CR9 publication-title: J Neurophysiol doi: 10.1152/jn.1999.82.2.829 contributor: fullname: KS Türker – volume: 187 start-page: 379 issue: 2 year: 1966 ident: 6290_CR2 publication-title: J Physiol doi: 10.1113/jphysiol.1966.sp008097 contributor: fullname: R Granit – volume: 28 start-page: 379 issue: 7 year: 2005 ident: 6290_CR11 publication-title: Trends Neurosci doi: 10.1016/j.tins.2005.05.007 contributor: fullname: KS Türker – volume: 239 start-page: 719 issue: 3 year: 2021 ident: 6290_CR3 publication-title: Exp Brain Res doi: 10.1007/s00221-020-05998-2 contributor: fullname: LP Kudina – volume: 68 start-page: 964 issue: 3 year: 1992 ident: 6290_CR6 publication-title: J Neurophysiol doi: 10.1152/jn.1992.68.3.964 contributor: fullname: RK Powers – volume: 14 start-page: e0225535 issue: 12 year: 2019 ident: 6290_CR5 publication-title: PLoS ONE doi: 10.1371/journal.pone.0225535 contributor: fullname: MG Özyurt – volume: 59 start-page: 389 year: 1973 ident: 6290_CR8 publication-title: Brain Res doi: 10.1016/0006-8993(73)90278-3 contributor: fullname: PC Schwindt – volume: 551 start-page: 419 issue: Pt 2 year: 2003 ident: 6290_CR10 publication-title: J Physiol doi: 10.1113/jphysiol.2003.044982 contributor: fullname: KS Türker |
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Snippet | This is a note challenging the claim by Kudina and Andreeva’s recent publication in Experimental Brain Research. In that publication, Kudina and Andreeva (Exp... This is a note challenging the claim by Kudina and Andreeva's recent publication in Experimental Brain Research. In that publication, Kudina and Andreeva (Exp... |
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SubjectTerms | Action Potentials Biomedical and Life Sciences Biomedicine H-Reflex Humans Letter to the Editor Motor Neurons Neurology Neurosciences |
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Title | An opinion on the 'delayed spikes' in human motoneurons |
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