Identification and characterization of a new pair of immunoglobulin-like receptors LMIR1 and 2 derived from murine bone marrow-derived mast cells

• Published in: Biochemical and biophysical research communications Vol. 307; no. 3; pp. 719 - 729
• Main Authors: Kumagai, Hidetoshi, Oki, Toshihiko, Tamitsu, Kaori, Feng, Si-Zhou, Ono, Masao, Nakajima, Hideaki, Bao, Ying-Chun, Kawakami, Yuko, Nagayoshi, Kazunari, Copeland, Neal G, Gilbert, Debra J, Jenkins, Nancy A, Kawakami, Toshiaki, Kitamura, Toshio
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.08.2003
• Subjects: Amino Acid Sequence; Animals; Base Sequence; Cell Line; Chromosome Mapping; Cloning, Molecular; Hematopoietic Stem Cells - physiology; Mast Cells - immunology; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Phosphoric Monoester Hydrolases - metabolism; Phosphorylation; Protein Structure, Tertiary; Protein Tyrosine Phosphatases - metabolism; Receptors, Immunologic - chemistry; Receptors, Immunologic - genetics; Receptors, Immunologic - metabolism; RNA, Messenger - biosynthesis; Tyrosine - metabolism

We have identified and characterized two mouse cDNAs in a mouse antigen-stimulated bone marrow-derived mast cell cDNA library, both of which encode type I transmembrane proteins. The genes were closely mapped in the distal region of mouse chromosome 11 and expressed not only in mast cells but also w...