Novel Roles of RNA m6A Methylation Regulators in the Occurrence of Alzheimer’s Disease and the Subtype Classification

• Published in: International journal of molecular sciences Vol. 23; no. 18; p. 10766
• Main Authors: Li, Min, Cheng, Wenli, Zhang, Luyun, Zhou, Cheng, Peng, Xinyue, Yu, Susu, Zhang, Wenjuan
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 15.09.2022; MDPI
• Subjects: Alzheimer's disease; Bioinformatics; biomarker; Classification; Clustering; consensus clustering; Datasets; Dementia disorders; Epigenetics; Gene expression; Genes; Immune system; m6A methylation; Methylation; N6-methyladenosine; Pathogenesis; Proteins; RNA modification; Systems development

Alzheimer’s disease (AD) is one of the most common forms of dementia, closely related to epigenetic factors. N6-methyladenosine (m6A) is the most abundant RNA modification, affecting the pathogenesis and development of neurodegenerative diseases. This study was the first exploration of the combined...