An overview on polyurethane-degrading enzymes
Polyurethanes (PUR) are durable synthetic polymers widely used in various industries, contributing significantly to global plastic consumption. PUR pose unique challenges in terms of degradability and recyclability, as they are characterised by intricate compositions and diverse formulations. Additi...
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Published in | Biotechnology advances Vol. 77; p. 108439 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
England
Elsevier Inc
01.12.2024
Elsevier |
Subjects | |
Online Access | Get full text |
ISSN | 0734-9750 1873-1899 1873-1899 |
DOI | 10.1016/j.biotechadv.2024.108439 |
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Abstract | Polyurethanes (PUR) are durable synthetic polymers widely used in various industries, contributing significantly to global plastic consumption. PUR pose unique challenges in terms of degradability and recyclability, as they are characterised by intricate compositions and diverse formulations. Additives and proprietary structures used in commercial PUR formulations further complicate recycling efforts, making the effective management of PUR waste a daunting task.
In this review, we delve into the complex challenge of enzymatic degradation of PUR, focusing on the structural and functional attributes of both enzymes and PUR. We also present documented native enzymes with reported efficacy in hydrolysing specific bonds within PUR, analysis of these enzyme structures, reaction mechanisms, substrate specificity, and binding site architecture. Furthermore, we propose essential features for the future redesign of enzymes to optimise PUR biodegradation efficiency. By outlining prospective research directions aimed at advancing the field of enzymatic biodegradation of PUR, we aim to contribute to the development of sustainable solutions for managing PUR waste and reducing environmental pollution. |
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AbstractList | Polyurethanes (PUR) are durable synthetic polymers widely used in various industries, contributing significantly to global plastic consumption. PUR pose unique challenges in terms of degradability and recyclability, as they are characterised by intricate compositions and diverse formulations. Additives and proprietary structures used in commercial PUR formulations further complicate recycling efforts, making the effective management of PUR waste a daunting task.
In this review, we delve into the complex challenge of enzymatic degradation of PUR, focusing on the structural and functional attributes of both enzymes and PUR. We also present documented native enzymes with reported efficacy in hydrolysing specific bonds within PUR, analysis of these enzyme structures, reaction mechanisms, substrate specificity, and binding site architecture. Furthermore, we propose essential features for the future redesign of enzymes to optimise PUR biodegradation efficiency. By outlining prospective research directions aimed at advancing the field of enzymatic biodegradation of PUR, we aim to contribute to the development of sustainable solutions for managing PUR waste and reducing environmental pollution. Polyurethanes (PUR) are durable synthetic polymers widely used in various industries, contributing significantly to global plastic consumption. PUR pose unique challenges in terms of degradability and recyclability, as they are characterised by intricate compositions and diverse formulations. Additives and proprietary structures used in commercial PUR formulations further complicate recycling efforts, making the effective management of PUR waste a daunting task.In this review, we delve into the complex challenge of enzymatic degradation of PUR, focusing on the structural and functional attributes of both enzymes and PUR. We also present documented native enzymes with reported efficacy in hydrolysing specific bonds within PUR, analysis of these enzyme structures, reaction mechanisms, substrate specificity, and binding site architecture. Furthermore, we propose essential features for the future redesign of enzymes to optimise PUR biodegradation efficiency. By outlining prospective research directions aimed at advancing the field of enzymatic biodegradation of PUR, we aim to contribute to the development of sustainable solutions for managing PUR waste and reducing environmental pollution. Polyurethanes (PUR) are durable synthetic polymers widely used in various industries, contributing significantly to global plastic consumption. PUR pose unique challenges in terms of degradability and recyclability, as they are characterised by intricate compositions and diverse formulations. Additives and proprietary structures used in commercial PUR formulations further complicate recycling efforts, making the effective management of PUR waste a daunting task. In this review, we delve into the complex challenge of enzymatic degradation of PUR, focusing on the structural and functional attributes of both enzymes and PUR. We also present documented native enzymes with reported efficacy in hydrolysing specific bonds within PUR, analysis of these enzyme structures, reaction mechanisms, substrate specificity, and binding site architecture. Furthermore, we propose essential features for the future redesign of enzymes to optimise PUR biodegradation efficiency. By outlining prospective research directions aimed at advancing the field of enzymatic biodegradation of PUR, we aim to contribute to the development of sustainable solutions for managing PUR waste and reducing environmental pollution.Polyurethanes (PUR) are durable synthetic polymers widely used in various industries, contributing significantly to global plastic consumption. PUR pose unique challenges in terms of degradability and recyclability, as they are characterised by intricate compositions and diverse formulations. Additives and proprietary structures used in commercial PUR formulations further complicate recycling efforts, making the effective management of PUR waste a daunting task. In this review, we delve into the complex challenge of enzymatic degradation of PUR, focusing on the structural and functional attributes of both enzymes and PUR. We also present documented native enzymes with reported efficacy in hydrolysing specific bonds within PUR, analysis of these enzyme structures, reaction mechanisms, substrate specificity, and binding site architecture. Furthermore, we propose essential features for the future redesign of enzymes to optimise PUR biodegradation efficiency. By outlining prospective research directions aimed at advancing the field of enzymatic biodegradation of PUR, we aim to contribute to the development of sustainable solutions for managing PUR waste and reducing environmental pollution. |
ArticleNumber | 108439 |
Author | André, Isabelle Góra, Artur Raczyńska, Agata |
Author_xml | – sequence: 1 givenname: Agata surname: Raczyńska fullname: Raczyńska, Agata organization: Tunneling Group, Biotechnology Centre, Silesian University of Technology, ul. Krzywoustego 8, 44-100 Gliwice, Poland – sequence: 2 givenname: Artur surname: Góra fullname: Góra, Artur email: a.gora@tunnelinggroup.pl organization: Tunneling Group, Biotechnology Centre, Silesian University of Technology, ul. Krzywoustego 8, 44-100 Gliwice, Poland – sequence: 3 givenname: Isabelle surname: André fullname: André, Isabelle email: isabelle.andre@insa-toulouse.fr organization: Toulouse Biotechnology Institute, TBI, Université de Toulouse, CNRS, INRAE, INSA, 135 avenue de Rangueil, F-31077 Toulouse Cedex, France |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/39241969$$D View this record in MEDLINE/PubMed https://hal.science/hal-04739428$$DView record in HAL |
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CitedBy_id | crossref_primary_10_1002_ange_202419535 crossref_primary_10_1016_j_jhazmat_2024_136659 crossref_primary_10_1002_anie_202419535 crossref_primary_10_1021_acssuschemeng_4c10512 crossref_primary_10_3390_polym17020169 crossref_primary_10_1016_j_csbj_2024_12_004 |
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Keywords | Biodegradation Hydrolysis Enzyme structure Biocatalysis Polymer recycling Synthetic polymers Enzymatic degradation Polyurethanes Environmental biotechnology |
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Snippet | Polyurethanes (PUR) are durable synthetic polymers widely used in various industries, contributing significantly to global plastic consumption. PUR pose unique... |
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SubjectTerms | Biocatalysis Biodegradation Biodegradation, Environmental Environmental biotechnology Enzymatic degradation Enzyme structure Enzymes - chemistry Enzymes - metabolism Hydrolysis Life Sciences Polymer recycling Polyurethanes Polyurethanes - chemistry Substrate Specificity Synthetic polymers |
Title | An overview on polyurethane-degrading enzymes |
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