miR‑203a‑3p.1 is involved in the regulation of osteogenic differentiation by directly targeting Smad9 in MM‑MSCs

• Published in: Oncology letters Vol. 18; no. 6; pp. 6339 - 6346
• Main Authors: Fan, Fang‑Yi, Deng, Rui, Qiu, Ling, Wen, Qin, Zeng, Yunjing, Gao, Li, Zhang, Chen, Kong, Peiyan, Zhong, Jiangfan, Zeng, Ningyu, Li, Zhengyu, Su, Yi, Zhang, Xi
• Format: Journal Article
• Language: English
• Published: Athens Spandidos Publications UK Ltd 17.10.2019; D.A. Spandidos
• Subjects: Biological products; Bone marrow; Immunoglobulins; Multiple myeloma; Oncology; Proteins; Stem cells; Studies; China

MicroRNAs (miRNAs) have emerged as important regulators of bone development and regeneration. The aim of the present study was to determine whether miR-203a-3p.1 is involved in osteogenic differentiation of multiple myeloma (MM)-mesenchymal stem cells (MSCs) and the potential underlying mechanism. M...