Microcomputed tomography-based structural analysis of various bone tissue regeneration models

• Published in: Nature protocols Vol. 6; no. 1; pp. 105 - 110
• Main Authors: Gazit, Dan, Kallai, Ilan, Mizrahi, Olga, Tawackoli, Wafa, Gazit, Zulma, Pelled, Gadi
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.01.2011; Nature Publishing Group
• Subjects: Analytical Chemistry; Animals; Biological Techniques; Biomedical and Life Sciences; Bone and Bones - pathology; Bone and Bones - physiology; Bone and Bones - ultrastructure; Bone Regeneration; Bones; Computational Biology/Bioinformatics; Design; Fractures; Health aspects; Life Sciences; Mechanical properties; Medical research; Methods; Mice; Microarrays; Models, Biological; Organic Chemistry; Protocol; Regenerative medicine; Skeletal system; Stem cells; Structural analysis; Technology application; Tissue engineering; Tissues; Tomography; X-Ray Microtomography - methods; United States

Microcomputed tomography (microCT) analysis is a powerful tool for the evaluation of bone tissue because it provides access to the 3D microarchitecture of the bone. It is invaluable for regenerative medicine as it provides the researcher with the opportunity to explore the skeletal system both in vi...