PKCα: Prospects in Regulating Insulin Resistance and AD

• Published in: Trends in endocrinology and metabolism Vol. 32; no. 6; pp. 341 - 350
• Main Authors: Mishra, Devanshi, Dey, Chinmoy Sankar
• Format: Journal Article
• Language: English
• Published: United States Elsevier Ltd 01.06.2021
• Subjects: Alzheimer Disease; Alzheimer’s disease; Endocrinology and Metabolism; Humans; Insulin; Insulin Resistance; insulin signaling; PKCα; Protein Kinase C-alpha - metabolism; Signal Transduction; insulin signaling; Alzheimer’s disease; PKCα; insulin resistance

Protein kinase C alpha (PKCα) is known to participate in various signaling pathways due to its ubiquitous and dynamic characteristics. Previous studies report that PKCα abrogates peripheral insulin resistance, and recent publications show that it takes part in regulating Alzheimer’s disease (AD). Ba...