Zooming in on common immune evasion mechanisms of pathogens in phagolysosomes: potential broad-spectrum therapeutic targets against infectious diseases

Abstract The intracellular viral, bacterial, or parasitic pathogens evade the host immune challenges to propagate and cause fatal diseases. The microbes overpower host immunity at various levels including during entry into host cells, phagosome formation, phagosome maturation, phagosome–lysosome fus...

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Published inFEMS microbiology reviews Vol. 47; no. 1; pp. 1 - 18
Main Authors Selvapandiyan, Angamuthu, Puri, Niti, Kumar, Pankaj, Alam, Anwar, Ehtesham, Nasreen Zafar, Griffin, George, Hasnain, Seyed Ehtesham
Format Journal Article
LanguageEnglish
Published England Oxford University Press 01.01.2023
Subjects
Acidification
Agonists
Antigen presentation
Antigens
Apoptosis
Autophagy
BCG
BCG vaccines
Communicable diseases
Communicable Diseases - metabolism
Cytosol
Development and progression
Drug development
Health aspects
Humans
Immune Evasion
Immune system
Infectious diseases
Inflammation
Inflammatory response
Intracellular
Lymphocytes T
Macrophages - metabolism
Macrophages - microbiology
Parasitic diseases
Pathogenic microorganisms
Pathogens
Phagocytosis
Phagolysosomes
Phagosomes
Phagosomes - metabolism
Phagosomes - microbiology
Reactive oxygen species
Therapeutic applications
Therapeutic targets
Zooming
India
apoptosis
agonist
phagosomes
antagonist
drug target
intracellular pathogens
Online AccessGet full text
ISSN1574-6976
0168-6445
1574-6976
DOI10.1093/femsre/fuac041

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Abstract Abstract The intracellular viral, bacterial, or parasitic pathogens evade the host immune challenges to propagate and cause fatal diseases. The microbes overpower host immunity at various levels including during entry into host cells, phagosome formation, phagosome maturation, phagosome–lysosome fusion forming phagolysosomes, acidification of phagolysosomes, and at times after escape into the cytosol. Phagolysosome is the final organelle in the phagocyte with sophisticated mechanisms to degrade the pathogens. The immune evasion strategies by the pathogens include the arrest of host cell apoptosis, decrease in reactive oxygen species, the elevation of Th2 anti-inflammatory response, avoidance of autophagy and antigen cross-presentation pathways, and escape from phagolysosomal killing. Since the phagolysosome organelle in relation to infection/cure is seldom discussed in the literature, we summarize here the common host as well as pathogen targets manipulated or utilized by the pathogens established in phagosomes and phagolysosomes, to hijack the host immune system for their benefit. These common molecules or pathways can be broad-spectrum therapeutic targets for drug development for intervention against infectious diseases caused by different intracellular pathogens. Broad-spectrum therapeutic phagolysosomal targets against various types of pathogens and the available therapeicstics.
AbstractList The intracellular viral, bacterial, or parasitic pathogens evade the host immune challenges to propagate and cause fatal diseases. The microbes overpower host immunity at various levels including during entry into host cells, phagosome formation, phagosome maturation, phagosome-lysosome fusion forming phagolysosomes, acidification of phagolysosomes, and at times after escape into the cytosol. Phagolysosome is the final organelle in the phagocyte with sophisticated mechanisms to degrade the pathogens. The immune evasion strategies by the pathogens include the arrest of host cell apoptosis, decrease in reactive oxygen species, the elevation of Th2 anti-inflammatory response, avoidance of autophagy and antigen cross-presentation pathways, and escape from phagolysosomal killing. Since the phagolysosome organelle in relation to infection/cure is seldom discussed in the literature, we summarize here the common host as well as pathogen targets manipulated or utilized by the pathogens established in phagosomes and phagolysosomes, to hijack the host immune system for their benefit. These common molecules or pathways can be broad-spectrum therapeutic targets for drug development for intervention against infectious diseases caused by different intracellular pathogens.
The intracellular viral, bacterial, or parasitic pathogens evade the host immune challenges to propagate and cause fatal diseases. The microbes overpower host immunity at various levels including during entry into host cells, phagosome formation, phagosome maturation, phagosome-lysosome fusion forming phagolysosomes, acidification of phagolysosomes, and at times after escape into the cytosol. Phagolysosome is the final organelle in the phagocyte with sophisticated mechanisms to degrade the pathogens. The immune evasion strategies by the pathogens include the arrest of host cell apoptosis, decrease in reactive oxygen species, the elevation of Th2 anti-inflammatory response, avoidance of autophagy and antigen cross-presentation pathways, and escape from phagolysosomal killing. Since the phagolysosome organelle in relation to infection/cure is seldom discussed in the literature, we summarize here the common host as well as pathogen targets manipulated or utilized by the pathogens established in phagosomes and phagolysosomes, to hijack the host immune system for their benefit. These common molecules or pathways can be broad-spectrum therapeutic targets for drug development for intervention against infectious diseases caused by different intracellular pathogens. Keywords: agonist, antagonist, apoptosis, drug target, intracellular pathogens, phagosomes
Abstract The intracellular viral, bacterial, or parasitic pathogens evade the host immune challenges to propagate and cause fatal diseases. The microbes overpower host immunity at various levels including during entry into host cells, phagosome formation, phagosome maturation, phagosome–lysosome fusion forming phagolysosomes, acidification of phagolysosomes, and at times after escape into the cytosol. Phagolysosome is the final organelle in the phagocyte with sophisticated mechanisms to degrade the pathogens. The immune evasion strategies by the pathogens include the arrest of host cell apoptosis, decrease in reactive oxygen species, the elevation of Th2 anti-inflammatory response, avoidance of autophagy and antigen cross-presentation pathways, and escape from phagolysosomal killing. Since the phagolysosome organelle in relation to infection/cure is seldom discussed in the literature, we summarize here the common host as well as pathogen targets manipulated or utilized by the pathogens established in phagosomes and phagolysosomes, to hijack the host immune system for their benefit. These common molecules or pathways can be broad-spectrum therapeutic targets for drug development for intervention against infectious diseases caused by different intracellular pathogens. Broad-spectrum therapeutic phagolysosomal targets against various types of pathogens and the available therapeicstics.
The intracellular viral, bacterial, or parasitic pathogens evade the host immune challenges to propagate and cause fatal diseases. The microbes overpower host immunity at various levels including during entry into host cells, phagosome formation, phagosome maturation, phagosome-lysosome fusion forming phagolysosomes, acidification of phagolysosomes, and at times after escape into the cytosol. Phagolysosome is the final organelle in the phagocyte with sophisticated mechanisms to degrade the pathogens. The immune evasion strategies by the pathogens include the arrest of host cell apoptosis, decrease in reactive oxygen species, the elevation of Th2 anti-inflammatory response, avoidance of autophagy and antigen cross-presentation pathways, and escape from phagolysosomal killing. Since the phagolysosome organelle in relation to infection/cure is seldom discussed in the literature, we summarize here the common host as well as pathogen targets manipulated or utilized by the pathogens established in phagosomes and phagolysosomes, to hijack the host immune system for their benefit. These common molecules or pathways can be broad-spectrum therapeutic targets for drug development for intervention against infectious diseases caused by different intracellular pathogens.The intracellular viral, bacterial, or parasitic pathogens evade the host immune challenges to propagate and cause fatal diseases. The microbes overpower host immunity at various levels including during entry into host cells, phagosome formation, phagosome maturation, phagosome-lysosome fusion forming phagolysosomes, acidification of phagolysosomes, and at times after escape into the cytosol. Phagolysosome is the final organelle in the phagocyte with sophisticated mechanisms to degrade the pathogens. The immune evasion strategies by the pathogens include the arrest of host cell apoptosis, decrease in reactive oxygen species, the elevation of Th2 anti-inflammatory response, avoidance of autophagy and antigen cross-presentation pathways, and escape from phagolysosomal killing. Since the phagolysosome organelle in relation to infection/cure is seldom discussed in the literature, we summarize here the common host as well as pathogen targets manipulated or utilized by the pathogens established in phagosomes and phagolysosomes, to hijack the host immune system for their benefit. These common molecules or pathways can be broad-spectrum therapeutic targets for drug development for intervention against infectious diseases caused by different intracellular pathogens.
Audience Academic
Author Selvapandiyan, Angamuthu
Alam, Anwar
Kumar, Pankaj
Griffin, George
Puri, Niti
Ehtesham, Nasreen Zafar
Hasnain, Seyed Ehtesham
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  surname: Selvapandiyan
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  givenname: Niti
  surname: Puri
  fullname: Puri, Niti
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  givenname: Pankaj
  surname: Kumar
  fullname: Kumar, Pankaj
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  surname: Alam
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  givenname: Nasreen Zafar
  surname: Ehtesham
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  fullname: Griffin, George
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  surname: Hasnain
  fullname: Hasnain, Seyed Ehtesham
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Cites_doi 10.1371/journal.ppat.1006165
10.1016/j.tube.2016.02.001
10.3389/fcimb.2018.00330
10.3389/fcimb.2017.00038
10.1016/j.ijid.2020.09.1429
10.1084/jem.20051239
10.1016/j.imlet.2004.12.007
10.3389/fphar.2022.806568
10.1038/s41598-017-12753-1
10.1002/iid3.295
10.1371/journal.pntd.0007424
10.1016/S2213-2600(20)30104-1
10.1128/IAI.74.5.2613-2618.2006
10.1371/journal.ppat.1000628
10.1021/jm010066k
10.3389/fcimb.2017.00347
10.1016/j.bmcl.2019.06.048
10.1074/jbc.M111.286120
10.1083/jcb.202110151
10.1007/s10875-021-01163-8
10.1111/j.1600-0854.2010.01050.x
10.1242/jcs.114.7.1283
10.1007/s11302-016-9544-1
10.1046/j.1365-3083.2000.00808.x
10.1046/j.1365-2958.2003.03657.x
10.1074/jbc.M116.716514
10.1080/07391102.2019.1595150
10.4049/jimmunol.1000702
10.1016/j.fsi.2016.05.028
10.1016/j.intimp.2022.108536
10.1186/s12879-017-2473-y
10.1078/0171-9335-00247
10.1016/j.vaccine.2014.05.009
10.1016/j.mam.2006.08.005
10.4049/jimmunol.180.5.3148
10.1165/rcmb.2005-0140OC
10.1046/j.1462-5822.2001.00127.x
10.3390/microorganisms8071013
10.1016/j.micinf.2008.11.007
10.1016/j.ajpath.2011.05.053
10.1111/j.1469-0691.2010.03237.x
10.2174/1570163817666200121143036
10.3389/fimmu.2021.636078
10.1016/j.molbiopara.2007.12.010
10.1016/j.chom.2017.04.004
10.1038/srep14854
10.1016/j.devcel.2021.10.006
10.1016/j.micinf.2015.05.005
10.3389/fimmu.2022.864031
10.1093/emboj/17.11.3124
10.3389/fmicb.2020.00242
10.1016/j.cell.2011.11.021
10.1038/srep40418
10.1016/j.bjid.2016.10.011
10.3389/fmicb.2019.01173
10.1371/journal.pbio.1001246
10.2147/DDDT.S353494
10.1155/2016/3845247
10.1074/jbc.M111.316125
10.1016/j.csbj.2022.04.002
10.1039/C7MT00284J
10.3389/fmicb.2018.02617
10.1111/jnc.15118
10.1016/j.tube.2010.09.001
10.1038/s41591-021-01397-4
10.1371/journal.ppat.1006551
10.1038/srep16320
10.1016/j.intimp.2015.07.020
10.1016/j.chom.2015.05.005
10.1038/14075
10.1016/S0092-8674(00)80754-0
10.1371/journal.pone.0008769
10.3389/fimmu.2020.598444
10.1111/cmi.12311
10.1128/JVI.00709-20
10.1016/j.cell.2020.10.039
10.1073/pnas.2016650117
10.1080/00325481.2020.1855921
10.1177/1753425919881176
10.3389/fcimb.2021.624094
10.1038/sj.onc.1203084
10.2147/IDR.S346869
10.1038/srep39492
10.1038/mt.2014.31
10.1038/s41421-021-00268-z
10.1128/IAI.68.5.2671-2684.2000
10.1038/s41586-021-03269-w
10.1074/mcp.RA119.001841
10.1371/journal.ppat.1004471
10.1016/j.meegid.2021.105202
10.1016/j.bbrc.2009.06.152
10.1016/j.cell.2005.06.043
10.1126/science.1227026
10.1074/jbc.M402794200
10.1074/jbc.M109.091645
10.1038/nrd4088
10.1165/rcmb.2010-0319OC
10.1007/s10753-016-0417-0
10.1111/febs.15166
10.7554/eLife.23905
10.1021/acs.jmedchem.2c00614
10.1073/pnas.0737613100
10.4049/jimmunol.1101231
10.1139/o02-142
10.1074/jbc.M204232200
10.1016/j.mehy.2020.110380
10.1074/jbc.M304546200
10.1038/srep35917
10.1038/nrmicro2128
10.1016/j.chom.2015.05.004
10.1016/j.chom.2015.05.003
10.1016/j.tube.2010.03.006
10.1073/pnas.160257897
10.1371/journal.ppat.1007982
10.7164/antibiotics.25.343
10.1111/j.1462-5822.2012.01767.x
10.1186/s12967-020-02339-3
10.1074/jbc.M104550200
10.1016/j.ijmm.2018.08.008
10.1016/j.csbj.2021.01.034
10.1111/cmi.13253
10.1371/journal.pntd.0004570
10.1128/IAI.00222-19
10.1155/2019/1356540
10.1107/S2059798321011219
10.3389/fimmu.2020.00962
10.1159/000319864
10.1111/j.1462-5822.2009.01337.x
10.1016/j.ijtb.2018.08.004
10.1371/journal.ppat.1009576
10.1038/s41418-021-00781-4
10.1016/j.metop.2021.100116
10.1002/jmv.26728
10.4049/jimmunol.0900276
10.1016/S0140-6736(00)02727-6
10.1371/journal.pone.0190490
10.4049/jimmunol.181.4.2651
10.1111/j.1348-0421.1998.tb02354.x
10.1016/S1473-3099(20)30132-8
10.3389/fcimb.2018.00084
10.1038/ncb1526
10.1038/s41598-019-45800-0
10.1038/s41598-017-03514-1
10.1016/B978-0-12-394390-3.00003-3
10.1002/jmv.27405
10.3389/fnmol.2020.00093
10.3390/cancers13071511
10.1016/j.apsb.2022.02.011
10.1186/s12964-017-0177-y
10.1046/j.1365-2958.2000.02021.x
10.1038/labinvest.2017.137
10.1038/s41598-019-42687-9
10.1111/j.1365-3083.2011.02663.x
10.3390/pathogens11030310
10.3389/fcimb.2017.00350
10.1128/AAC.01498-21
10.1186/s13578-022-00770-1
10.1038/aps.2015.91
10.1016/j.micinf.2015.03.010
10.1016/j.atherosclerosis.2014.01.014
10.1038/s41577-020-0285-6
10.1016/j.exphem.2010.04.003
10.1042/EBC20220001
10.1007/s00281-020-00794-0
10.1046/j.1365-2958.1998.00846.x
10.1038/s41467-022-30654-4
10.1371/journal.pone.0224239
10.1016/j.cell.2016.08.017
10.1073/pnas.0800404105
10.1128/IAI.67.8.4055-4063.1999
10.1111/cmi.12260
10.1016/j.cbpa.2009.03.021
10.1016/j.celrep.2020.107746
10.1371/journal.ppat.1006459
10.1016/j.smim.2015.03.009
10.1080/15548627.2022.2153569
10.1093/infdis/jiaa445
10.1074/jbc.RA120.012491
10.1016/j.devcel.2020.12.010
10.1155/2021/8874339
10.1128/IAI.01589-06
10.1128/iai.56.2.363-369.1988
10.1016/j.cell.2006.01.034
10.1371/journal.ppat.1003499
10.1016/j.dci.2021.104257
10.1515/hsz-2016-0274
10.1038/s41467-021-27426-x
10.1111/imr.13065
10.1016/j.celrep.2021.109126
10.1016/j.bmc.2020.115940
10.1073/pnas.1902788117
10.1371/journal.pone.0069619
10.1111/pim.12521
10.1111/cmi.13003
10.1016/j.celrep.2022.111282
10.3389/fimmu.2018.01161
10.1016/j.micres.2017.09.001
10.1242/jcs.113.19.3531
10.1111/j.1462-5822.2008.01239.x
10.1016/j.immuni.2016.02.026
10.1007/s00294-021-01198-9
10.1038/sj.emboj.7601511
10.4049/jimmunol.157.8.3559
10.1016/j.cellimm.2007.02.001
10.3389/fmicb.2015.00946
10.1016/j.bbagen.2006.11.016
10.3389/fcimb.2014.00180
10.1016/j.cell.2007.04.043
10.1016/j.cell.2015.05.009
10.1016/j.imbio.2013.03.003
10.1021/acsinfecdis.7b00268
10.1016/j.ejmech.2016.10.028
10.1371/journal.pone.0206459
ContentType Journal Article
Copyright The Author(s) 2022. Published by Oxford University Press on behalf of FEMS. 2022
The Author(s) 2022. Published by Oxford University Press on behalf of FEMS.
COPYRIGHT 2023 Oxford University Press
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0168-6445
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IsPeerReviewed true
IsScholarly true
Issue 1
Keywords apoptosis
agonist
phagosomes
antagonist
drug target
intracellular pathogens
Language English
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References Arango Duque (2023011615070897700_bib6) 2019; 15
Flannagan (2023011615070897700_bib52) 2009; 7
Miao (2023011615070897700_bib120) 2015; 161
Wei (2023011615070897700_bib204) 2020; 94
Mottola (2023011615070897700_bib123) 2014; 4
Muccini (2023011615070897700_bib126) 2022; 40
Gerry (2023011615070897700_bib60) 2014; 233
Madan (2023011615070897700_bib114) 2012; 287
Drevinek (2023011615070897700_bib41) 2010; 16
Kang (2023011615070897700_bib89) 2005; 202
Garcia-Rodriguez (2023011615070897700_bib58) 2020; 8
Selvapandiyan (2023011615070897700_bib168) 2004; 279
Chang (2023011615070897700_bib23) 2022; 12
Elahi (2023011615070897700_bib45) 2022; 105
Canton (2023011615070897700_bib17) 2012; 14
Gupta (2023011615070897700_bib70) 2020; 38
Cui (2023011615070897700_bib31) 2020; 21
Parapini (2023011615070897700_bib143) 2022; 66
Seto (2023011615070897700_bib171) 2009; 387
Naqvi (2023011615070897700_bib131) 2017; 7
Negi (2023011615070897700_bib132) 2019; 10
Miao (2023011615070897700_bib119) 2021; 56
Ranatunga (2023011615070897700_bib149) 2020; 287
Singh (2023011615070897700_bib176) 2019; 14
Gordon (2023011615070897700_bib67) 2016; 44
Soe-Lin (2023011615070897700_bib178) 2010; 38
Zhang (2023011615070897700_bib216) 2021; 7
Dey (2023011615070897700_bib39) 2020; 88
Philips (2023011615070897700_bib146) 2008; 10
Das (2023011615070897700_bib34) 1998; 42
Yin (2023011615070897700_bib213) 2022; 126
Alphonse (2023011615070897700_bib5) 2021; 11
Volchenkov (2023011615070897700_bib198) 2012; 75
Sun (2023011615070897700_bib183) 2013; 9
Yimcharoen (2023011615070897700_bib212) 2022; 15
Yu (2023011615070897700_bib214) 2017; 205
Vaca (2023011615070897700_bib192) 2021; 156
Luo (2023011615070897700_bib112) 2017; 21
Gomez Barroso (2023011615070897700_bib64) 2022; 78
Sharma (2023011615070897700_bib173) 2018; 308
Kim (2023011615070897700_bib93) 2005; 99
Kruger (2023011615070897700_bib100) 2002; 277
Churina (2023011615070897700_bib28) 2012; 2012
Polando (2023011615070897700_bib148) 2018; 40
Pandey (2023011615070897700_bib142) 2017; 7
Chen (2023011615070897700_bib25) 2016; 6
Ismail (2023011615070897700_bib82) 2022; 13
Ho (2023011615070897700_bib76) 2008; 180
Vannier-Santos (2023011615070897700_bib193) 1995; 67
Miorin (2023011615070897700_bib122) 2020; 117
Placido (2023011615070897700_bib147) 2006; 244
Jindani (2023011615070897700_bib87) 2010; 90
Figliuolo (2023011615070897700_bib50) 2017; 13
Wardini (2023011615070897700_bib201) 2019; 9
Chen (2023011615070897700_bib24) 2021; 56
Singh (2023011615070897700_bib177) 2021; 27
Muefong (2023011615070897700_bib127) 2020; 11
Hilda (2023011615070897700_bib75) 2020; 26
Winberg (2023011615070897700_bib207) 2009; 11
Sharma (2023011615070897700_bib174) 2017; 7
Wannigama (2023011615070897700_bib200) 2020; 101
Kifle (2023011615070897700_bib92) 2021; 11
Watson (2023011615070897700_bib203) 2015; 17
Duan (2023011615070897700_bib42) 2016; 55
Choy (2023011615070897700_bib27) 2012; 338
Levy (2023011615070897700_bib106) 2020; 117
Acharya (2023011615070897700_bib3) 2022; 307
Wang (2023011615070897700_bib199) 2018; 13
Kong (2023011615070897700_bib98) 2017; 13
Banerjee (2023011615070897700_bib8) 2020; 22
Vidal (2023011615070897700_bib195) 1996; 157
Gutierrez (2023011615070897700_bib71) 2008; 181
Kolli (2023011615070897700_bib96) 2008; 158
Patel (2023011615070897700_bib144) 2008; 105
Hayn (2023011615070897700_bib74) 2021; 35
Das (2023011615070897700_bib35) 2000; 52
Kolyvushko (2023011615070897700_bib97) 2020; 8
Liu (2023011615070897700_bib110) 2017; 7
Arasaki (2023011615070897700_bib7) 2010; 11
Adam (2023011615070897700_bib4) 2021; 12
Gordon (2023011615070897700_bib66) 2016; 166
Real (2023011615070897700_bib151) 2014; 16
Kushawaha (2023011615070897700_bib101) 2022
Mubin (2023011615070897700_bib125) 2018; 13
Osanya (2023011615070897700_bib139) 2011; 179
Song (2023011615070897700_bib180) 2022; 20
Jang (2023011615070897700_bib83) 2021; 28
Cebrian (2023011615070897700_bib18) 2011; 147
Kircheis (2023011615070897700_bib94) 2020; 11
Black (2023011615070897700_bib10) 2000; 37
Gandhi (2023011615070897700_bib56) 2020; 18
Magnet (2023011615070897700_bib115) 2010; 90
Chen (2023011615070897700_bib26) 2016; 39
Danelishvili (2023011615070897700_bib33) 2015; 17
Satarker (2023011615070897700_bib163) 2021; 133
Boissan (2023011615070897700_bib12) 2018; 98
Dhiman (2023011615070897700_bib40) 2007; 1770
Khalil (2023011615070897700_bib91) 2021; 19
Sun (2023011615070897700_bib184) 2010; 5
Tigano (2023011615070897700_bib190) 2021; 591
McCluskey (2023011615070897700_bib118) 2002; 45
Spath (2023011615070897700_bib181) 2000; 97
Yang (2023011615070897700_bib210) 2017; 6
Duell (2023011615070897700_bib44) 2012; 188
Selvapandiyan (2023011615070897700_bib169) 2014; 32
Jayachandran (2023011615070897700_bib85) 2007; 130
Pahari (2023011615070897700_bib140) 2016; 6
Das (2023011615070897700_bib36) 2019; 9
Gupta (2023011615070897700_bib69) 2021; 68
Huo (2023011615070897700_bib79) 2022; 16
Lenne (2023011615070897700_bib104) 2018; 9
Deng (2023011615070897700_bib37) 2022
Gogulamudi (2023011615070897700_bib63) 2015; 6
Thakur (2023011615070897700_bib188) 2019; 2019
Kreykenbohm (2023011615070897700_bib99) 2002; 81
Kuznik (2023011615070897700_bib102) 2011; 186
Rigano (2023011615070897700_bib155) 2014; 16
Garcia-Aguilar (2023011615070897700_bib57) 2016; 2016
Jiang (2023011615070897700_bib86) 2021; 30
Liu (2023011615070897700_bib111) 2018; 8
Huynh (2023011615070897700_bib81) 2010; 2
O'Leary (2023011615070897700_bib136) 2011; 45
Greene (2023011615070897700_bib68) 2022; 13
Hottiger (2023011615070897700_bib78) 1998; 17
Tsoi (2023011615070897700_bib191) 2021; 13
Zhao (2023011615070897700_bib217) 2012; 69
Campillo-Navarro (2023011615070897700_bib16) 2018; 9
Saeki (2023011615070897700_bib161) 1972; 25
Omahdi (2023011615070897700_bib138) 2020; 295
Schor (2023011615070897700_bib165) 2018; 4
Holm (2023011615070897700_bib77) 2001; 3
Huynh (2023011615070897700_bib80) 2007; 26
Macedo (2023011615070897700_bib113) 2015; 28
Gidon (2023011615070897700_bib62) 2017; 13
Ohashi (2023011615070897700_bib137) 2012; 287
Bowen (2023011615070897700_bib14) 2002; 277
Nairz (2023011615070897700_bib129) 2009; 11
Seif (2023011615070897700_bib166) 2017; 15
Baska (2023011615070897700_bib9) 2022; 11
da Silva Escada (2023011615070897700_bib32) 2017; 17
Fratti (2023011615070897700_bib53) 2003; 100
Reuter (2023011615070897700_bib153) 2020; 19
Nguyen (2023011615070897700_bib134) 2021; 12
Li (2023011615070897700_bib108) 2016; 124
Xu (2023011615070897700_bib209) 2022
Karam (2023011615070897700_bib90) 2021; 93
Verma (2023011615070897700_bib194) 2017; 13
Lerm (2023011615070897700_bib105) 2006; 74
Zhu (2023011615070897700_bib219) 2021; 223
Fu (2023011615070897700_bib54) 2020; 18
Chahar (2023011615070897700_bib19) 2018; 65
Rickard (2023011615070897700_bib154) 2013; 8
Brazier (2023011615070897700_bib15) 2020; 42
La (2023011615070897700_bib103) 2018; 10
Tanaka (2023011615070897700_bib186) 2005; 33
Rink (2023011615070897700_bib156) 2005; 122
Wu (2023011615070897700_bib208) 2015; 36
Fernandez-Figueroa (2023011615070897700_bib48) 2016; 10
Li (2023011615070897700_bib109) 2022; 98
Manik (2023011615070897700_bib117) 2022; 94
Finlay (2023011615070897700_bib51) 2006; 124
Rodrigues (2023011615070897700_bib158) 2019; 21
Naik (2023011615070897700_bib128) 2022; 13
Chakrabarty (2023011615070897700_bib21) 1998; 28
Eskelinen (2023011615070897700_bib46) 2006; 27
Nielsen (2023011615070897700_bib135) 1999; 1
Miklossy (2023011615070897700_bib121) 2013; 12
Santos (2023011615070897700_bib162) 2013; 218
Ferrari (2023011615070897700_bib49) 1999; 97
Sellge (2023011615070897700_bib167) 2015; 27
Stebbing (2023011615070897700_bib182) 2020; 20
Klatt (2023011615070897700_bib95) 2019; 13
Regli (2023011615070897700_bib152) 2020; 31
Zhang (2023011615070897700_bib215) 2022; 65
Fung (2023011615070897700_bib55) 2022; 12
Thepaut (2023011615070897700_bib189) 2021; 17
Netea (2023011615070897700_bib133) 2020; 20
Tasker (2023011615070897700_bib187) 2019; 29
Selvapandiyan (2023011615070897700_bib170) 2009; 183
Zhu (2023011615070897700_bib218) 2015; 5
Ruiz-Ruiz (2023011615070897700_bib159) 2020; 13
Chakaya (2023011615070897700_bib20) 2020; 8
Handa (2023011615070897700_bib72) 2007; 9
Wilson (2023011615070897700_bib206) 1988; 56
Muangsombut (2023011615070897700_bib124) 2017; 7
Wassermann (2023011615070897700_bib202) 2015; 17
Aboudounya (2023011615070897700_bib2) 2021; 2021
Gargouri (2023011615070897700_bib59) 2021; 146
Fan (2023011615070897700_bib47) 2016; 98
Dey (2023011615070897700_bib38) 2007; 75
Man (2023011615070897700_bib116) 2022; 66
Shukla (2023011615070897700_bib175) 2014; 10
Pan (2023011615070897700_bib141) 2014; 22
Whitworth (2023011615070897700_bib205) 2000; 356
Ghosh (2023011615070897700_bib61) 2020; 183
Solvik (2023011615070897700_bib179) 2022; 221
Vintonyak (2023011615070897700_bib197) 2009; 13
Yang (2023011615070897700_bib211) 2017; 2017
Collins (2023011615070897700_bib30) 2015; 17
Harrison (2023011615070897700_bib73) 2002; 80
Schnettger (2023011615070897700_bib164) 2017; 21
Clemens (2023011615070897700_bib29) 2000; 68
Johnson (2023011615070897700_bib88) 2015; 17
Li (2023011615070897700_bib107) 2020; 11
Shang (2023011615070897700_bib172) 1999; 18
Nandan (2023011615070897700_bib130) 1999; 67
Bloomfield (2023011615070897700_bib11) 2022; 42
Rastogi (2023011615070897700_bib150) 2016; 291
Abhishek (2023011615070897700_bib1) 2018; 8
Chandra (2023011615070897700_bib22) 2015; 5
Rupper (2023011615070897700_bib160) 2001; 114
Jani (2023011615070897700_bib84) 2010; 285
Takada (2023011615070897700_bib185) 2004; 279
Boitel (2023011615070897700_bib13) 2003; 49
Goody (2023011615070897700_bib65) 2017; 398
Petit-Jentreau (2023011615070897700_bib145) 2017; 7
Vinet (2023011615070897700_bib196) 2009; 5
Duclos (2023011615070897700_bib43) 2000; 113 Pt 19
Robinson (2023011615070897700_bib157) 2012; 10
References_xml – volume: 13
  start-page: e1006165
  year: 2017
  ident: 2023011615070897700_bib98
  article-title: Transcriptional profiling in experimental visceral leishmaniasis reveals a broad splenic inflammatory environment that conditions macrophages toward a disease-promoting phenotype
  publication-title: PLoS Pathog
  doi: 10.1371/journal.ppat.1006165
– volume: 98
  start-page: 13
  year: 2016
  ident: 2023011615070897700_bib47
  article-title: Impaired NK cells' activity and increased numbers of CD4 + CD25+ regulatory T cells in multidrug-resistant Mycobacterium tuberculosis patients
  publication-title: Tuberculosis
  doi: 10.1016/j.tube.2016.02.001
– volume: 8
  start-page: 330
  year: 2018
  ident: 2023011615070897700_bib1
  article-title: Transcriptional profile of Mycobacterium tuberculosis in an in vitro model of intraocular tuberculosis
  publication-title: Front Cell Infect Microbiol
  doi: 10.3389/fcimb.2018.00330
– volume: 7
  start-page: 38
  year: 2017
  ident: 2023011615070897700_bib142
  article-title: Mycobacterium tuberculosis peptidyl-prolyl isomerases are immunogenic, alter cytokine profile and aid in intracellular survival
  publication-title: Front Cell Infect Microbiol
  doi: 10.3389/fcimb.2017.00038
– volume: 101
  start-page: 52
  year: 2020
  ident: 2023011615070897700_bib200
  article-title: NOD2-dependent BCG-induced trained immunity: a way to regulate innate responses to SARS-COV2?
  publication-title: Int J Infect Dis
  doi: 10.1016/j.ijid.2020.09.1429
– volume: 202
  start-page: 987
  year: 2005
  ident: 2023011615070897700_bib89
  article-title: The human macrophage mannose receptor directs Mycobacterium tuberculosis lipoarabinomannan-mediated phagosome biogenesis
  publication-title: J Exp Med
  doi: 10.1084/jem.20051239
– volume: 99
  start-page: 45
  year: 2005
  ident: 2023011615070897700_bib93
  article-title: LY294002 inhibits LPS-induced no production through a inhibition of NF-KappaB activation: independent mechanism of phosphatidylinositol 3-kinase
  publication-title: Immunol Lett
  doi: 10.1016/j.imlet.2004.12.007
– volume: 13
  start-page: 806568
  year: 2022
  ident: 2023011615070897700_bib128
  article-title: Kinase inhibitors as potential therapeutic agents in the treatment of COVID-19
  publication-title: Front Pharmacol
  doi: 10.3389/fphar.2022.806568
– volume: 7
  start-page: 13240
  year: 2017
  ident: 2023011615070897700_bib131
  article-title: Role of mast cells in clearance of Leishmania through extracellular trap formation
  publication-title: Sci Rep
  doi: 10.1038/s41598-017-12753-1
– volume: 8
  start-page: 198
  year: 2020
  ident: 2023011615070897700_bib58
  article-title: Human mast cells exhibit an individualized pattern of antimicrobial responses
  publication-title: Immun Inflamm Dis
  doi: 10.1002/iid3.295
– volume: 13
  start-page: e0007424
  year: 2019
  ident: 2023011615070897700_bib95
  article-title: Leishmania tarentolae: taxonomic classification and its application as a promising biotechnological expression host
  publication-title: PLoS NeglTrop Dis
  doi: 10.1371/journal.pntd.0007424
– volume: 8
  start-page: 334
  year: 2020
  ident: 2023011615070897700_bib20
  article-title: Programmatic versus personalised approaches to managing the global epidemic of multidrug-resistant tuberculosis
  publication-title: Lancet Respir Med
  doi: 10.1016/S2213-2600(20)30104-1
– volume: 74
  start-page: 2613
  year: 2006
  ident: 2023011615070897700_bib105
  article-title: Leishmania donovani requires functional Cdc42 and Rac1 to prevent phagosomal maturation
  publication-title: Infect Immun
  doi: 10.1128/IAI.74.5.2613-2618.2006
– volume: 5
  start-page: e1000628
  year: 2009
  ident: 2023011615070897700_bib196
  article-title: The Leishmania donovani lipophosphoglycan excludes the vesicular proton-ATPase from phagosomes by impairing the recruitment of synaptotagmin V
  publication-title: PLoS Pathog
  doi: 10.1371/journal.ppat.1000628
– volume: 45
  start-page: 1151
  year: 2002
  ident: 2023011615070897700_bib118
  article-title: Serine-threonine protein phosphatase inhibitors: development of potential therapeutic strategies
  publication-title: J Med Chem
  doi: 10.1021/jm010066k
– volume: 7
  start-page: 347
  year: 2017
  ident: 2023011615070897700_bib145
  article-title: Purinergic signaling: a common path in the macrophage response against Mycobacterium tuberculosis and Toxoplasma gondii
  publication-title: Front Cell Infect Microbiol
  doi: 10.3389/fcimb.2017.00347
– volume: 29
  start-page: 2008
  year: 2019
  ident: 2023011615070897700_bib187
  article-title: Tapping the therapeutic potential of protein tyrosine phosphatase 4A with small molecule inhibitors
  publication-title: Bioorg Med Chem Lett
  doi: 10.1016/j.bmcl.2019.06.048
– volume: 287
  start-page: 5574
  year: 2012
  ident: 2023011615070897700_bib114
  article-title: Salmonella acquires lysosome-associated membrane protein 1 (LAMP1) on phagosomes from Golgi via SipC protein-mediated recruitment of host Syntaxin6
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M111.286120
– volume: 221
  start-page: e202110151
  year: 2022
  ident: 2023011615070897700_bib179
  article-title: Secretory autophagy maintains proteostasis upon lysosome inhibition
  publication-title: J Cell Biol
  doi: 10.1083/jcb.202110151
– volume: 42
  start-page: 266
  year: 2022
  ident: 2023011615070897700_bib11
  article-title: Immunogenicity and safety of COVID-19 mRNA vaccine in STAT1 GOF patients
  publication-title: J Clin Immunol
  doi: 10.1007/s10875-021-01163-8
– volume: 11
  start-page: 587
  year: 2010
  ident: 2023011615070897700_bib7
  article-title: Legionella pneumophila promotes functional interactions between plasma membrane syntaxins and Sec22b
  publication-title: Traffic
  doi: 10.1111/j.1600-0854.2010.01050.x
– volume: 114
  start-page: 1283
  year: 2001
  ident: 2023011615070897700_bib160
  article-title: P110-related PI 3-kinases regulate phagosome-phagosome fusion and phagosomal ph through a PKB/Akt dependent pathway in Dictyostelium
  publication-title: J Cell Sci
  doi: 10.1242/jcs.114.7.1283
– volume: 13
  start-page: 143
  year: 2017
  ident: 2023011615070897700_bib50
  article-title: The role of the P2×7 receptor in murine cutaneous leishmaniasis: aspects of inflammation and parasite control
  publication-title: Purinergic Sig
  doi: 10.1007/s11302-016-9544-1
– volume: 52
  start-page: 515
  year: 2000
  ident: 2023011615070897700_bib35
  article-title: Th1-specific bystander costimulation imparts resistance against Mycobacterium tuberculosis infection
  publication-title: Scand J Immunol
  doi: 10.1046/j.1365-3083.2000.00808.x
– start-page: 105457
  volume-title: Microb Pathog
  year: 2022
  ident: 2023011615070897700_bib101
  article-title: Leishmania donovani secretory protein nucleoside diphosphate kinase B localizes in its nucleus and prevents ATP mediated cytolysis of macrophages
– volume: 49
  start-page: 1493
  year: 2003
  ident: 2023011615070897700_bib13
  article-title: PknB kinase activity is regulated by phosphorylation in two Thr residues and dephosphorylation by PstP, the cognate phospho-Ser/Thr phosphatase, in Mycobacterium tuberculosis
  publication-title: Mol Microbiol
  doi: 10.1046/j.1365-2958.2003.03657.x
– volume: 291
  start-page: 14732
  year: 2016
  ident: 2023011615070897700_bib150
  article-title: Rab5 isoforms specifically regulate different modes of endocytosis in Leishmania
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M116.716514
– volume: 38
  start-page: 1083
  year: 2020
  ident: 2023011615070897700_bib70
  article-title: Mycobacterium tuberculosis nucleoside diphosphate kinase shows interaction with putative ATP binding cassette (ABC) transporter, Rv1273c
  publication-title: J Biomol Struct Dyn
  doi: 10.1080/07391102.2019.1595150
– volume: 186
  start-page: 4794
  year: 2011
  ident: 2023011615070897700_bib102
  article-title: Mechanism of endosomal tlr inhibition by antimalarial drugs and imidazoquinolines
  publication-title: J Immunol
  doi: 10.4049/jimmunol.1000702
– volume: 55
  start-page: 123
  year: 2016
  ident: 2023011615070897700_bib42
  article-title: Characterization of ADP ribosylation factor 1 gene from Exopalaemon carinicauda and its immune response to pathogens challenge and ammonia-N stress
  publication-title: Fish Shellfish Immunol
  doi: 10.1016/j.fsi.2016.05.028
– volume: 105
  start-page: 108536
  year: 2022
  ident: 2023011615070897700_bib45
  article-title: An updated overview of recent advances, challenges, and clinical considerations of IL-6 signaling blockade in severe coronavirus disease 2019 (COVID-19)
  publication-title: Int Immunopharmacol
  doi: 10.1016/j.intimp.2022.108536
– volume: 17
  start-page: 373
  year: 2017
  ident: 2023011615070897700_bib32
  article-title: Mortality in patients with HIV-1 and tuberculosis co-infection in Rio de Janeiro, Brazil - associated factors and causes of death
  publication-title: BMC Infect Dis
  doi: 10.1186/s12879-017-2473-y
– volume: 81
  start-page: 273
  year: 2002
  ident: 2023011615070897700_bib99
  article-title: The SNAREs vti1a and vti1b have distinct localization and snare complex partners
  publication-title: Eur J Cell Biol
  doi: 10.1078/0171-9335-00247
– volume: 32
  start-page: 3895
  year: 2014
  ident: 2023011615070897700_bib169
  article-title: Generation of growth arrested leishmania amastigotes: a tool to develop live attenuated vaccine candidates against visceral leishmaniasis
  publication-title: Vaccine
  doi: 10.1016/j.vaccine.2014.05.009
– volume: 27
  start-page: 495
  year: 2006
  ident: 2023011615070897700_bib46
  article-title: Roles of LAMP-1 and LAMP-2 in lysosome biogenesis and autophagy
  publication-title: Mol Aspects Med
  doi: 10.1016/j.mam.2006.08.005
– volume: 180
  start-page: 3148
  year: 2008
  ident: 2023011615070897700_bib76
  article-title: Vesicle-associated membrane protein-8/endobrevin negatively regulates phagocytosis of bacteria in dendritic cells
  publication-title: J Immunol
  doi: 10.4049/jimmunol.180.5.3148
– volume: 33
  start-page: 406
  year: 2005
  ident: 2023011615070897700_bib186
  article-title: Interleukin-10 induces inhibitory C/EBPpbeta through STAT-3 and represses HIV-1 transcription in macrophages
  publication-title: Am J Respir Cell Mol Biol
  doi: 10.1165/rcmb.2005-0140OC
– volume: 3
  start-page: 439
  year: 2001
  ident: 2023011615070897700_bib77
  article-title: Leishmania donovani lipophosphoglycan causes periphagosomal actin accumulation: correlation with impaired translocation of PKCalpha and defective phagosome maturation
  publication-title: Cell Microbiol
  doi: 10.1046/j.1462-5822.2001.00127.x
– volume: 8
  start-page: 1013
  year: 2020
  ident: 2023011615070897700_bib97
  article-title: Equine alphaherpesviruses require activation of the small gtpases Rac1 and Cdc for intracellular transport
  publication-title: Microorganisms
  doi: 10.3390/microorganisms8071013
– volume: 11
  start-page: 215
  year: 2009
  ident: 2023011615070897700_bib207
  article-title: Leishmania donovani lipophosphoglycan inhibits phagosomal maturation via action on membrane rafts
  publication-title: Microbes Infect
  doi: 10.1016/j.micinf.2008.11.007
– volume: 179
  start-page: 1329
  year: 2011
  ident: 2023011615070897700_bib139
  article-title: Pathogen-derived oligosaccharides improve innate immune response to intracellular parasite infection
  publication-title: Am J Pathol
  doi: 10.1016/j.ajpath.2011.05.053
– volume: 16
  start-page: 821
  year: 2010
  ident: 2023011615070897700_bib41
  article-title: Burkholderia cenocepacia in cystic fibrosis: epidemiology and molecular mechanisms of virulence
  publication-title: Clin Microbiol Infect
  doi: 10.1111/j.1469-0691.2010.03237.x
– volume: 18
  start-page: 307
  year: 2020
  ident: 2023011615070897700_bib56
  article-title: Collocating novel targets for tuberculosis (TB) drug discovery
  publication-title: Curr Drug Discov Technol
  doi: 10.2174/1570163817666200121143036
– volume: 12
  start-page: 636078
  year: 2021
  ident: 2023011615070897700_bib134
  article-title: Better together: current insights into phagosome-lysosome fusion
  publication-title: Front Immunol
  doi: 10.3389/fimmu.2021.636078
– volume: 158
  start-page: 163
  year: 2008
  ident: 2023011615070897700_bib96
  article-title: Leishmania-released nucleoside diphosphate kinase prevents ATP-mediated cytolysis of macrophages
  publication-title: Mol Biochem Parasitol
  doi: 10.1016/j.molbiopara.2007.12.010
– volume: 21
  start-page: 619
  year: 2017
  ident: 2023011615070897700_bib164
  article-title: A Rab20-dependent membrane trafficking pathway controls M. tuberculosis replication by regulating phagosome spaciousness and integrity
  publication-title: Cell Host Microbe
  doi: 10.1016/j.chom.2017.04.004
– volume: 5
  start-page: 14854
  year: 2015
  ident: 2023011615070897700_bib218
  article-title: Role of JAK-STAT signaling in maturation of phagosomes containing Staphylococcus aureus
  publication-title: Sci Rep
  doi: 10.1038/srep14854
– volume: 56
  start-page: 3250
  year: 2021
  ident: 2023011615070897700_bib24
  article-title: ORF3a of SARS-CoV-2 promotes lysosomal exocytosis-mediated viral egress
  publication-title: Dev Cell
  doi: 10.1016/j.devcel.2021.10.006
– volume: 17
  start-page: 628
  year: 2015
  ident: 2023011615070897700_bib33
  article-title: Mycobacterium avium MAV_2941 mimics phosphoinositol-3-kinase to interfere with macrophage phagosome maturation
  publication-title: Microbes Infect
  doi: 10.1016/j.micinf.2015.05.005
– volume: 13
  start-page: 864031
  year: 2022
  ident: 2023011615070897700_bib82
  article-title: Leishmania major centrin gene-deleted parasites generate skin resident memory T-cell immune response analogous to leishmanization
  publication-title: Front Immunol
  doi: 10.3389/fimmu.2022.864031
– volume: 17
  start-page: 3124
  year: 1998
  ident: 2023011615070897700_bib78
  article-title: Modulation of cytokine-induced HIV gene expression by competitive binding of transcription factors to the coactivator p300
  publication-title: EMBO J
  doi: 10.1093/emboj/17.11.3124
– volume: 11
  start-page: 242
  year: 2020
  ident: 2023011615070897700_bib107
  article-title: Characterization of Zika virus endocytic pathways in human glioblastoma cells
  publication-title: Front Microbiol
  doi: 10.3389/fmicb.2020.00242
– volume: 147
  start-page: 1355
  year: 2011
  ident: 2023011615070897700_bib18
  article-title: Sec22b regulates phagosomal maturation and antigen crosspresentation by dendritic cells
  publication-title: Cell
  doi: 10.1016/j.cell.2011.11.021
– volume: 2012
  start-page: 931291
  year: 2012
  ident: 2023011615070897700_bib28
  article-title: The role of Foxp3-expressing regulatory T cells and T helpers in immunopathogenesis of multidrug resistant pulmonary tuberculosis
  publication-title: Tuberc Res Treat
– volume: 7
  start-page: 40418
  year: 2017
  ident: 2023011615070897700_bib110
  article-title: Nf-KappaB activation is critical for bacterial lipoprotein tolerance-enhanced bactericidal activity in macrophages during microbial infection
  publication-title: Sci Rep
  doi: 10.1038/srep40418
– volume: 67
  start-page: 112
  year: 1995
  ident: 2023011615070897700_bib193
  article-title: Leishmanial protein kinase C modulates host cell infection via secreted acid phosphatase
  publication-title: Eur J Cell Biol
– volume: 21
  start-page: 155
  year: 2017
  ident: 2023011615070897700_bib112
  article-title: Imbalance of Th17 and Treg in peripheral blood mononuclear cells of active tuberculosis patients
  publication-title: Braz J Infect Dis
  doi: 10.1016/j.bjid.2016.10.011
– volume: 10
  start-page: 1173
  year: 2019
  ident: 2023011615070897700_bib132
  article-title: Curdlan limits Mycobacterium tuberculosis survival through STAT-1 regulated nitric oxide production
  publication-title: Front Microbiol
  doi: 10.3389/fmicb.2019.01173
– volume: 10
  start-page: e1001246
  year: 2012
  ident: 2023011615070897700_bib157
  article-title: Rise and fall, and rise again: phagosome maturation is controlled by two kinases and one phosphatase
  publication-title: PLoS Biol
  doi: 10.1371/journal.pbio.1001246
– volume: 16
  start-page: 991
  year: 2022
  ident: 2023011615070897700_bib79
  article-title: Therapeutic potential of janus kinase inhibitors for the management of interstitial lung disease
  publication-title: Drug Des Dev Ther
  doi: 10.2147/DDDT.S353494
– volume: 2016
  start-page: 3845247
  year: 2016
  ident: 2023011615070897700_bib57
  article-title: The mannose receptor is involved in the phagocytosis of mycobacteria-induced apoptotic cells
  publication-title: J Immunol Res
  doi: 10.1155/2016/3845247
– volume: 287
  start-page: 3885
  year: 2012
  ident: 2023011615070897700_bib137
  article-title: AMF-26, a novel inhibitor of the Golgi system, targeting ADP-ribosylation factor 1 (ARF1) with potential for cancer therapy
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M111.316125
– volume: 20
  start-page: 1785
  year: 2022
  ident: 2023011615070897700_bib180
  article-title: M(6)A-mediated modulation coupled with transcriptional regulation shapes long noncoding RNA repertoire of the cGAS-STING signaling
  publication-title: Comput Struct Biotechnol J
  doi: 10.1016/j.csbj.2022.04.002
– volume: 10
  start-page: 154
  year: 2018
  ident: 2023011615070897700_bib103
  article-title: Mobilization of iron from ferritin: new steps and details
  publication-title: Metall Integr Biometal Sci
  doi: 10.1039/C7MT00284J
– volume: 9
  start-page: 2617
  year: 2018
  ident: 2023011615070897700_bib104
  article-title: Characterization of a protein phosphatase type-1 and a kinase anchoring protein in Plasmodium falciparum
  publication-title: Front Microbiol
  doi: 10.3389/fmicb.2018.02617
– volume: 156
  start-page: 379
  year: 2021
  ident: 2023011615070897700_bib192
  article-title: Therapeutic potential of novel cell division cycle kinase 7 inhibitors on TDP-43-related pathogenesis such as frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS)
  publication-title: J Neurochem
  doi: 10.1111/jnc.15118
– volume: 90
  start-page: 354
  year: 2010
  ident: 2023011615070897700_bib115
  article-title: Leads for antitubercular compounds from kinase inhibitor library screens
  publication-title: Tuberculosis
  doi: 10.1016/j.tube.2010.09.001
– volume: 27
  start-page: 1131
  year: 2021
  ident: 2023011615070897700_bib177
  article-title: SARS-COV-2 variants of concern are emerging in India
  publication-title: Nat Med
  doi: 10.1038/s41591-021-01397-4
– volume: 13
  start-page: e1006551
  year: 2017
  ident: 2023011615070897700_bib62
  article-title: Persistent mycobacteria evade an antibacterial program mediated by phagolysosomal TLR7/8/MYD88 in human primary macrophages
  publication-title: PLoS Pathog
  doi: 10.1371/journal.ppat.1006551
– volume: 5
  start-page: 16320
  year: 2015
  ident: 2023011615070897700_bib22
  article-title: Mycobacterium tuberculosis inhibits RAB7 recruitment to selectively modulate autophagy flux in macrophages
  publication-title: Sci Rep
  doi: 10.1038/srep16320
– start-page: 1
  year: 2022
  ident: 2023011615070897700_bib37
  article-title: TRAF6 autophagic degradation by avibirnavirus VP3 inhibits antiviral innate immunity via blocking NFKB/NF-KappaB activation
  publication-title: Autophagy
– volume: 28
  start-page: 554
  year: 2015
  ident: 2023011615070897700_bib113
  article-title: The pentavalent antimonial therapy against experimental Leishmania amazonensis infection is more effective under the inhibition of the NF-KappaB pathway
  publication-title: Int Immunopharmacol
  doi: 10.1016/j.intimp.2015.07.020
– volume: 17
  start-page: 820
  year: 2015
  ident: 2023011615070897700_bib30
  article-title: Cyclic GMP-AMP synthase is an innate immune DNA sensor for Mycobacterium tuberculosis
  publication-title: Cell Host Microbe
  doi: 10.1016/j.chom.2015.05.005
– volume: 1
  start-page: 376
  year: 1999
  ident: 2023011615070897700_bib135
  article-title: Rab5 regulates motility of early endosomes on microtubules
  publication-title: Nat Cell Biol
  doi: 10.1038/14075
– volume: 97
  start-page: 435
  year: 1999
  ident: 2023011615070897700_bib49
  article-title: A coat protein on phagosomes involved in the intracellular survival of mycobacteria
  publication-title: Cell
  doi: 10.1016/S0092-8674(00)80754-0
– volume: 5
  start-page: e8769
  year: 2010
  ident: 2023011615070897700_bib184
  article-title: Mycobacterial nucleoside diphosphate kinase blocks phagosome maturation in murine raw 264.7 macrophages
  publication-title: PLoS ONE
  doi: 10.1371/journal.pone.0008769
– volume: 11
  start-page: 598444
  year: 2020
  ident: 2023011615070897700_bib94
  article-title: NF-KappaB pathway as a potential target for treatment of critical stage COVID-19 patients
  publication-title: Front Immunol
  doi: 10.3389/fimmu.2020.598444
– volume: 16
  start-page: 1549
  year: 2014
  ident: 2023011615070897700_bib151
  article-title: Cell-to-cell transfer of Leishmania amazonensis amastigotes is mediated by immunomodulatory LAMP-rich parasitophorous extrusions
  publication-title: Cell Microbiol
  doi: 10.1111/cmi.12311
– volume: 94
  start-page: e00709
  year: 2020
  ident: 2023011615070897700_bib204
  article-title: Porcine reproductive and respiratory syndrome virus utilizes viral apoptotic mimicry as an alternative pathway to infect host cells
  publication-title: J Virol
  doi: 10.1128/JVI.00709-20
– volume: 183
  start-page: 1520
  year: 2020
  ident: 2023011615070897700_bib61
  article-title: Beta-coronaviruses use lysosomes for egress instead of the biosynthetic secretory pathway
  publication-title: Cell
  doi: 10.1016/j.cell.2020.10.039
– volume: 117
  start-page: 28344
  year: 2020
  ident: 2023011615070897700_bib122
  article-title: SARS-COV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling
  publication-title: Proc Nat Acad Sci USA
  doi: 10.1073/pnas.2016650117
– volume: 133
  start-page: 489
  year: 2021
  ident: 2023011615070897700_bib163
  article-title: JAK-STAT pathway inhibition and their implications in COVID-19 therapy
  publication-title: Postgrad Med
  doi: 10.1080/00325481.2020.1855921
– volume: 26
  start-page: 240
  year: 2020
  ident: 2023011615070897700_bib75
  article-title: Role of neutrophils in tuberculosis: a bird's eye view
  publication-title: Innate Immun
  doi: 10.1177/1753425919881176
– volume: 11
  start-page: 624094
  year: 2021
  ident: 2023011615070897700_bib5
  article-title: Interferons: tug of war between bacteria and their host
  publication-title: Front Cell Infect Microbiol
  doi: 10.3389/fcimb.2021.624094
– volume: 18
  start-page: 6725
  year: 1999
  ident: 2023011615070897700_bib172
  article-title: The induction and activation of STAT1 by all-trans-retinoic acid are mediated by RAR beta signaling pathways in breast cancer cells
  publication-title: Oncogene
  doi: 10.1038/sj.onc.1203084
– volume: 15
  start-page: 399
  year: 2022
  ident: 2023011615070897700_bib212
  article-title: The regulation of ManLAM-related gene expression in Mycobacterium tuberculosis with different drug resistance profiles following isoniazid treatment
  publication-title: Infect Drug Resist
  doi: 10.2147/IDR.S346869
– volume: 6
  start-page: 39492
  year: 2016
  ident: 2023011615070897700_bib140
  article-title: Infergen stimulated macrophages restrict Mycobacterium tuberculosis growth by autophagy and release of nitric oxide
  publication-title: Sci Rep
  doi: 10.1038/srep39492
– volume: 22
  start-page: 940
  year: 2014
  ident: 2023011615070897700_bib141
  article-title: Aptamer against mannose-capped lipoarabinomannan inhibits virulent Mycobacterium tuberculosis infection in mice and rhesus monkeys
  publication-title: Mol Ther J Amer Soc Gene Ther
  doi: 10.1038/mt.2014.31
– volume: 7
  start-page: 31
  year: 2021
  ident: 2023011615070897700_bib216
  article-title: The SARS-COV-2 protein ORF3a inhibits fusion of autophagosomes with lysosomes
  publication-title: Cell Discov
  doi: 10.1038/s41421-021-00268-z
– volume: 68
  start-page: 2671
  year: 2000
  ident: 2023011615070897700_bib29
  article-title: Deviant expression of Rab5 on phagosomes containing the intracellular pathogens Mycobacterium tuberculosis and Legionella pneumophila is associated with altered phagosomal fate
  publication-title: Infect Immun
  doi: 10.1128/IAI.68.5.2671-2684.2000
– volume: 591
  start-page: 477
  year: 2021
  ident: 2023011615070897700_bib190
  article-title: Nuclear sensing of breaks in mitochondrial DNA enhances immune surveillance
  publication-title: Nature
  doi: 10.1038/s41586-021-03269-w
– volume: 19
  start-page: 900
  year: 2020
  ident: 2023011615070897700_bib153
  article-title: Proteomic analysis of Salmonella-modified membranes reveals adaptations to macrophage hosts
  publication-title: Mol Cell Proteomics
  doi: 10.1074/mcp.RA119.001841
– volume: 10
  start-page: e1004471
  year: 2014
  ident: 2023011615070897700_bib175
  article-title: Mycobacterium tuberculosis lipoprotein LprG binds lipoarabinomannan and determines its cell envelope localization to control phagolysosomal fusion
  publication-title: PLoS Pathog
  doi: 10.1371/journal.ppat.1004471
– volume: 98
  start-page: 105202
  year: 2022
  ident: 2023011615070897700_bib109
  article-title: Polymorphisms of SLC11A1(NRAMP1) rs17235409 associated with and susceptibility to spinal tuberculosis in a southern Han Chinese population
  publication-title: Infect Infect Genet Evol
  doi: 10.1016/j.meegid.2021.105202
– volume: 387
  start-page: 272
  year: 2009
  ident: 2023011615070897700_bib171
  article-title: Dissection of Rab7 localization on Mycobacterium tuberculosis phagosome
  publication-title: Biochem Biophys Res Commun
  doi: 10.1016/j.bbrc.2009.06.152
– volume: 122
  start-page: 735
  year: 2005
  ident: 2023011615070897700_bib156
  article-title: Rab conversion as a mechanism of progression from early to late endosomes
  publication-title: Cell
  doi: 10.1016/j.cell.2005.06.043
– volume: 21
  start-page: 1633
  year: 2020
  ident: 2023011615070897700_bib31
  article-title: Protective effect of GYY4137, a watersoluble hydrogen sulfidereleasing molecule, on intestinal ischemiareperfusion
  publication-title: Mol Med Rep
– volume: 338
  start-page: 1072
  year: 2012
  ident: 2023011615070897700_bib27
  article-title: The legionella effector RavZ inhibits host autophagy through irreversible Atg8 deconjugation
  publication-title: Science
  doi: 10.1126/science.1227026
– volume: 279
  start-page: 25703
  year: 2004
  ident: 2023011615070897700_bib168
  article-title: Centrin gene disruption impairs stage-specific basal body duplication and cell cycle progression in leishmania
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M402794200
– volume: 285
  start-page: 19162
  year: 2010
  ident: 2023011615070897700_bib84
  article-title: Inhibition of NF-KappaB signaling by quinacrine is cytotoxic to human colon carcinoma cell lines and is synergistic in combination with tumor necrosis factor-related apoptosis-inducing ligand (trail) or oxaliplatin
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M109.091645
– volume: 12
  start-page: 611
  year: 2013
  ident: 2023011615070897700_bib121
  article-title: Therapeutic modulators of STAT signalling for human diseases
  publication-title: Nat Rev Drug Discov
  doi: 10.1038/nrd4088
– volume: 45
  start-page: 172
  year: 2011
  ident: 2023011615070897700_bib136
  article-title: IL-10 blocks phagosome maturation in Mycobacterium tuberculosis-infected human macrophages
  publication-title: Am J Respir Cell Mol Biol
  doi: 10.1165/rcmb.2010-0319OC
– volume: 39
  start-page: 1814
  year: 2016
  ident: 2023011615070897700_bib26
  article-title: The P2×7 receptor involved in gp120-induced cell injury in BV2 microglia
  publication-title: Inflammation
  doi: 10.1007/s10753-016-0417-0
– volume: 287
  start-page: 1777
  year: 2020
  ident: 2023011615070897700_bib149
  article-title: Leishmania aethiopica cell-to-cell spreading involves caspase-3, AkT, and NF-KappaB but not PKC-delta activation and involves uptake of LAMP-1-positive bodies containing parasites
  publication-title: FEBS J
  doi: 10.1111/febs.15166
– volume: 6
  start-page: e23905
  year: 2017
  ident: 2023011615070897700_bib210
  article-title: Elucidation of the anti-autophagy mechanism of the Legionella effector ravz using semisynthetic LC3 proteins
  publication-title: Elife
  doi: 10.7554/eLife.23905
– volume: 65
  start-page: 10133
  year: 2022
  ident: 2023011615070897700_bib215
  article-title: Polo-like kinase 1 inhibitors in human cancer therapy: development and therapeutic potential
  publication-title: J Med Chem
  doi: 10.1021/acs.jmedchem.2c00614
– volume: 100
  start-page: 5437
  year: 2003
  ident: 2023011615070897700_bib53
  article-title: Mycobacterium tuberculosis glycosylated phosphatidylinositol causes phagosome maturation arrest
  publication-title: Proc Natl Acad Sci
  doi: 10.1073/pnas.0737613100
– volume: 188
  start-page: 781
  year: 2012
  ident: 2023011615070897700_bib44
  article-title: Innate transcriptional networks activated in bladder in response to uropathogenic Escherichia coli drive diverse biological pathways and rapid synthesis of IL-10 for defense against bacterial urinary tract infection
  publication-title: J Immunol
  doi: 10.4049/jimmunol.1101231
– volume: 80
  start-page: 509
  year: 2002
  ident: 2023011615070897700_bib73
  article-title: Phagocytosis and the microtubule cytoskeleton
  publication-title: Biochem Cell Biol
  doi: 10.1139/o02-142
– volume: 277
  start-page: 34997
  year: 2002
  ident: 2023011615070897700_bib14
  article-title: C-Myc represses and Miz-1 activates the murine natural resistance-associated protein 1 promoter
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M204232200
– volume: 146
  start-page: 110380
  year: 2021
  ident: 2023011615070897700_bib59
  article-title: Cyclin dependent kinase inhibitors as a new potential therapeutic option in management of COVID-19
  publication-title: Med Hypotheses
  doi: 10.1016/j.mehy.2020.110380
– volume: 279
  start-page: 4750
  year: 2004
  ident: 2023011615070897700_bib185
  article-title: Flavopiridol inhibits NF-KappaB activation induced by various carcinogens and inflammatory agents through inhibition of IkappaBalpha kinase and p65 phosphorylation: abrogation of cyclin D1, cyclooxygenase-2, and matrix metalloprotease-9
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M304546200
– volume: 6
  start-page: 35917
  year: 2016
  ident: 2023011615070897700_bib25
  article-title: HBV core promoter mutations and AKT upregulate S-phase kinase-associated protein 2 to promote postoperative hepatocellular carcinoma progression
  publication-title: Sci Rep
  doi: 10.1038/srep35917
– volume: 7
  start-page: 355
  year: 2009
  ident: 2023011615070897700_bib52
  article-title: Antimicrobial mechanisms of phagocytes and bacterial evasion strategies
  publication-title: Nat Rev Microbiol
  doi: 10.1038/nrmicro2128
– volume: 17
  start-page: 811
  year: 2015
  ident: 2023011615070897700_bib203
  article-title: The cytosolic sensor cGAS etects Mycobacterium tuberculosis DNA to induce type I interferons and activate autophagy
  publication-title: Cell Host Microbe
  doi: 10.1016/j.chom.2015.05.004
– volume: 17
  start-page: 799
  year: 2015
  ident: 2023011615070897700_bib202
  article-title: Mycobacterium tuberculosis differentially activates cGAS- and inflammasome-dependent intracellular immune responses through ESX-1
  publication-title: Cell Host Microbe
  doi: 10.1016/j.chom.2015.05.003
– volume: 90
  start-page: 168
  year: 2010
  ident: 2023011615070897700_bib87
  article-title: Challenges to the development of new drugs and regimens for tuberculosis
  publication-title: Tuberculosis
  doi: 10.1016/j.tube.2010.03.006
– volume: 97
  start-page: 9258
  year: 2000
  ident: 2023011615070897700_bib181
  article-title: Lipophosphoglycan is a virulence factor distinct from related glycoconjugates in the protozoan parasite Leishmania major
  publication-title: Proc Nat Acad Sci USA
  doi: 10.1073/pnas.160257897
– volume: 15
  start-page: e1007982
  year: 2019
  ident: 2023011615070897700_bib6
  article-title: The host cell secretory pathway mediates the export of Leishmania virulence factors out of the parasitophorous vacuole
  publication-title: PLoS Pathog
  doi: 10.1371/journal.ppat.1007982
– volume: 25
  start-page: 343
  year: 1972
  ident: 2023011615070897700_bib161
  article-title: Cyclamidomycin (desdanine), an inhibitor of nucleoside diphosphokinase of Escherichia coli
  publication-title: J Antibiot
  doi: 10.7164/antibiotics.25.343
– volume: 14
  start-page: 937
  year: 2012
  ident: 2023011615070897700_bib17
  article-title: Disruption of the fusion of Leishmania parasitophorous vacuoles with ER vesicles results in the control of the infection
  publication-title: Cell Microbiol
  doi: 10.1111/j.1462-5822.2012.01767.x
– volume: 18
  start-page: 164
  year: 2020
  ident: 2023011615070897700_bib54
  article-title: Why tocilizumab could be an effective treatment for severe COVID-19?
  publication-title: J Transl Med
  doi: 10.1186/s12967-020-02339-3
– volume: 277
  start-page: 2620
  year: 2002
  ident: 2023011615070897700_bib100
  article-title: Protein-tyrosine phosphatase MEG2 is expressed by human neutrophils. Localization to the phagosome and activation by polyphosphoinositides
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M104550200
– volume: 308
  start-page: 1000
  year: 2018
  ident: 2023011615070897700_bib173
  article-title: Mycobacterium indicus pranii protein MIP_05962 induces Th1 cell mediated immune response in mice
  publication-title: Int J Med Microbiol
  doi: 10.1016/j.ijmm.2018.08.008
– volume: 19
  start-page: 976
  year: 2021
  ident: 2023011615070897700_bib91
  article-title: Chemokines and chemokine receptors during COVID-19 infection
  publication-title: Computat Struct Biotechnol J
  doi: 10.1016/j.csbj.2021.01.034
– volume: 22
  start-page: e13253
  year: 2020
  ident: 2023011615070897700_bib8
  article-title: Leishmania infection triggers hepcidin-mediated proteasomal degradation of Nramp1 to increase phagolysosomal iron availability
  publication-title: Cell Microbiol
  doi: 10.1111/cmi.13253
– volume: 10
  start-page: e0004570
  year: 2016
  ident: 2023011615070897700_bib48
  article-title: Down-regulation of TLR and JAK/STAT pathway genes is associated with diffuse cutaneous leishmaniasis: a gene expression analysis in NK cells from patients infected with Leishmania mexicana
  publication-title: PLoS NeglTrop Dis
  doi: 10.1371/journal.pntd.0004570
– volume: 88
  start-page: e00222
  year: 2020
  ident: 2023011615070897700_bib39
  article-title: Combination of Mycobacterium indicus pranii and heat-induced promastigotes cures drug-resistant Leishmania infection: critical role of Interleukin-6-producing classical dendritic cells
  publication-title: Infect Immun
  doi: 10.1128/IAI.00222-19
– volume: 2019
  start-page: 1356540
  year: 2019
  ident: 2023011615070897700_bib188
  article-title: Intracellular pathogens: host immunity and microbial persistence strategies
  publication-title: J Immunol Res
  doi: 10.1155/2019/1356540
– volume: 78
  start-page: 30
  year: 2022
  ident: 2023011615070897700_bib64
  article-title: X-ray diffraction and in vivo studies reveal the quinary structure of Trypanosoma cruzi nucleoside diphosphate kinase 1: a novel helical oligomer structure
  publication-title: Acta Crystallogr Sect D Struct Biol
  doi: 10.1107/S2059798321011219
– volume: 11
  start-page: 962
  year: 2020
  ident: 2023011615070897700_bib127
  article-title: Neutrophils in tuberculosis-associated inflammation and lung pathology
  publication-title: Front Immunol
  doi: 10.3389/fimmu.2020.00962
– volume: 2
  start-page: 522
  year: 2010
  ident: 2023011615070897700_bib81
  article-title: Inactivation of macrophage Rab7 by Burkholderia cenocepacia
  publication-title: J Innate Immun
  doi: 10.1159/000319864
– volume: 11
  start-page: 1365
  year: 2009
  ident: 2023011615070897700_bib129
  article-title: SLC11A1 limits intracellular growth of Salmonella enterica sv. Typhimurium by promoting macrophage immune effector functions and impairing bacterial iron acquisition
  publication-title: Cell Microbiol
  doi: 10.1111/j.1462-5822.2009.01337.x
– volume: 65
  start-page: 335
  year: 2018
  ident: 2023011615070897700_bib19
  article-title: Potential of adjunctive Mycobacterium W (MIP) immunotherapy in reducing the duration of standard chemotherapy against tuberculosis
  publication-title: Indian J Tuberc
  doi: 10.1016/j.ijtb.2018.08.004
– volume: 17
  start-page: e1009576
  year: 2021
  ident: 2023011615070897700_bib189
  article-title: DC/L-sign recognition of spike glycoprotein promotes SARS-COV-2 trans-infection and can be inhibited by a glycomimetic antagonist
  publication-title: PLoS Pathog
  doi: 10.1371/journal.ppat.1009576
– volume: 28
  start-page: 2745
  year: 2021
  ident: 2023011615070897700_bib83
  article-title: PLK1/vimentin signaling facilitates immune escape by recruiting SMAD2/3 to PD-L1 promoter in metastatic lung adenocarcinoma
  publication-title: Cell Death Differ
  doi: 10.1038/s41418-021-00781-4
– volume: 11
  start-page: 100116
  year: 2021
  ident: 2023011615070897700_bib92
  article-title: Bruton tyrosine kinase inhibitors as potential therapeutic agents for COVID-19: a review
  publication-title: Metabol Open
  doi: 10.1016/j.metop.2021.100116
– volume: 93
  start-page: 1843
  year: 2021
  ident: 2023011615070897700_bib90
  article-title: Mtor inhibition in COVID-19: a commentary and review of efficacy in RNA viruses
  publication-title: J Med Virol
  doi: 10.1002/jmv.26728
– volume: 183
  start-page: 1813
  year: 2009
  ident: 2023011615070897700_bib170
  article-title: Intracellular replication-deficient Leishmania donovani induces long lasting protective immunity against visceral leishmaniasis
  publication-title: J Immunol
  doi: 10.4049/jimmunol.0900276
– volume: 356
  start-page: 1051
  year: 2000
  ident: 2023011615070897700_bib205
  article-title: Effect of HIV-1 and increasing immunosuppression on malaria parasitaemia and clinical episodes in adults in rural Uganda: a cohort study
  publication-title: Lancet
  doi: 10.1016/S0140-6736(00)02727-6
– volume: 13
  start-page: e0190490
  year: 2018
  ident: 2023011615070897700_bib199
  article-title: The expression profiles of immune genes in Mus musculus macrophages during Staphylococcus aureus infection
  publication-title: PLoS ONE
  doi: 10.1371/journal.pone.0190490
– volume: 181
  start-page: 2651
  year: 2008
  ident: 2023011615070897700_bib71
  article-title: Nf-Kappa B activation controls phagolysosome fusion-mediated killing of mycobacteria by macrophages
  publication-title: J Immunol
  doi: 10.4049/jimmunol.181.4.2651
– volume: 42
  start-page: 795
  year: 1998
  ident: 2023011615070897700_bib34
  article-title: Leishmania donovani infection of a susceptible host results in apoptosis of Th1-like cells: rescue of anti-leishmanial CMI by providing Th1-specific bystander costimulation
  publication-title: Microbiol Immunol
  doi: 10.1111/j.1348-0421.1998.tb02354.x
– volume: 20
  start-page: 400
  year: 2020
  ident: 2023011615070897700_bib182
  article-title: COVID-19: combining antiviral and anti-inflammatory treatments
  publication-title: Lancet Infect Dis
  doi: 10.1016/S1473-3099(20)30132-8
– volume: 8
  start-page: 84
  year: 2018
  ident: 2023011615070897700_bib111
  article-title: The ATP-P2×7 signaling axis is an essential sentinel for intracellular Clostridium difficile pathogen-induced inflammasome activation
  publication-title: Front Cell Infect Microbiol
  doi: 10.3389/fcimb.2018.00084
– volume: 9
  start-page: 121
  year: 2007
  ident: 2023011615070897700_bib72
  article-title: Shigella ipgb1 promotes bacterial entry through the ELMO-Dock180 machinery
  publication-title: Nat Cell Biol
  doi: 10.1038/ncb1526
– volume: 9
  start-page: 9825
  year: 2019
  ident: 2023011615070897700_bib36
  article-title: Nucleic acid sensing activates the innate cytosolic surveillance pathway and promotes parasite survival in visceral leishmaniasis
  publication-title: Sci Rep
  doi: 10.1038/s41598-019-45800-0
– volume: 7
  start-page: 3354
  year: 2017
  ident: 2023011615070897700_bib174
  article-title: Efficacy and safety of Mycobacterium indicus pranii as an adjunct therapy in category II pulmonary tuberculosis in a randomized trial
  publication-title: Sci Rep
  doi: 10.1038/s41598-017-03514-1
– volume: 69
  start-page: 67
  year: 2012
  ident: 2023011615070897700_bib217
  article-title: Iron transport machinery of human cells: players and their interactions
  publication-title: Curr Top Membr
  doi: 10.1016/B978-0-12-394390-3.00003-3
– volume: 94
  start-page: 869
  year: 2022
  ident: 2023011615070897700_bib117
  article-title: Role of toll-like receptors in modulation of cytokine storm signaling in SARS-COV-2-induced COVID-19
  publication-title: J Med Virol
  doi: 10.1002/jmv.27405
– volume: 13
  start-page: 93
  year: 2020
  ident: 2023011615070897700_bib159
  article-title: P2×7 receptor antagonism as a potential therapy in amyotrophic lateral sclerosis
  publication-title: Front Mol Neurosci
  doi: 10.3389/fnmol.2020.00093
– volume: 13
  start-page: 1511
  year: 2021
  ident: 2023011615070897700_bib191
  article-title: Targeting the IL-6/STAT3 signalling cascade to reverse tamoxifen resistance in estrogen receptor positive breast cancer
  publication-title: Cancers
  doi: 10.3390/cancers13071511
– volume: 12
  start-page: 2619
  year: 2022
  ident: 2023011615070897700_bib23
  article-title: Discovery of ARF1-targeting inhibitor demethylzeylasteral as a potential agent against breast cancer
  publication-title: Acta Pharmaceut Sin B
  doi: 10.1016/j.apsb.2022.02.011
– volume: 15
  start-page: 23
  year: 2017
  ident: 2023011615070897700_bib166
  article-title: The role of JAK-STAT signaling pathway and its regulators in the fate of T helper cells
  publication-title: Cell Commun Signal
  doi: 10.1186/s12964-017-0177-y
– volume: 37
  start-page: 515
  year: 2000
  ident: 2023011615070897700_bib10
  article-title: The RhoGAP activity of the Yersinia pseudotuberculosis cytotoxin yope is required for antiphagocytic function and virulence
  publication-title: Mol Microbiol
  doi: 10.1046/j.1365-2958.2000.02021.x
– volume: 98
  start-page: 164
  year: 2018
  ident: 2023011615070897700_bib12
  article-title: The NDPK/NME superfamily: state of the art
  publication-title: Lab Invest
  doi: 10.1038/labinvest.2017.137
– volume: 9
  start-page: 6247
  year: 2019
  ident: 2023011615070897700_bib201
  article-title: Neutrophil properties in healthy and Leishmania infantum-naturally infected dogs
  publication-title: Sci Rep
  doi: 10.1038/s41598-019-42687-9
– volume: 75
  start-page: 1
  year: 2012
  ident: 2023011615070897700_bib198
  article-title: The 2011 Nobel Prize in physiology or medicine
  publication-title: Scand J Immunol
  doi: 10.1111/j.1365-3083.2011.02663.x
– volume: 11
  start-page: 310
  year: 2022
  ident: 2023011615070897700_bib9
  article-title: The role of nuclear factor Kappa B (NF-KappaB) in the immune response against parasites
  publication-title: Pathogens
  doi: 10.3390/pathogens11030310
– volume: 7
  start-page: 350
  year: 2017
  ident: 2023011615070897700_bib124
  article-title: Burkholderia pseudomallei evades NRAMP1 (SLS11A1)- and NADPH oxidase-mediated killing in macrophages and exhibits NRAMP1-dependent virulence gene expression
  publication-title: Front Cell Infect Microbiol
  doi: 10.3389/fcimb.2017.00350
– volume: 66
  start-page: e0149821
  year: 2022
  ident: 2023011615070897700_bib143
  article-title: In vitro antimalarial activity of inhibitors of the human gtpase Rac1
  publication-title: Antimicrob Agents Chemother
  doi: 10.1128/AAC.01498-21
– volume: 12
  start-page: 36
  year: 2022
  ident: 2023011615070897700_bib55
  article-title: SARS-COV-2 NSP13 helicase suppresses interferon signaling by perturbing JAK1 phosphorylation of STAT1
  publication-title: Cell Bioscience
  doi: 10.1186/s13578-022-00770-1
– volume: 36
  start-page: 1395
  year: 2015
  ident: 2023011615070897700_bib208
  article-title: Toll-like receptors: potential targets for lupus treatment
  publication-title: Acta Pharmacol Sin
  doi: 10.1038/aps.2015.91
– volume: 17
  start-page: 369
  year: 2015
  ident: 2023011615070897700_bib88
  article-title: Porphyromonas gingivalis attenuates ATP-mediated inflammasome activation and HMGB1 release through expression of a nucleoside-diphosphate kinase
  publication-title: Microbes Infect
  doi: 10.1016/j.micinf.2015.03.010
– volume: 233
  start-page: 537
  year: 2014
  ident: 2023011615070897700_bib60
  article-title: Effect of low extracellular ph on NF-KappaB activation in macrophages
  publication-title: Atherosclerosis
  doi: 10.1016/j.atherosclerosis.2014.01.014
– volume: 20
  start-page: 375
  year: 2020
  ident: 2023011615070897700_bib133
  article-title: Defining trained immunity and its role in health and disease
  publication-title: Nat Rev Immunol
  doi: 10.1038/s41577-020-0285-6
– volume: 38
  start-page: 609
  year: 2010
  ident: 2023011615070897700_bib178
  article-title: Both NRAMP1 and DMT1 are necessary for efficient macrophage iron recycling
  publication-title: Exp Hematol
  doi: 10.1016/j.exphem.2010.04.003
– volume: 66
  start-page: 371
  year: 2022
  ident: 2023011615070897700_bib116
  article-title: Mechanisms of resistance to tyrosine kinase inhibitors in liver cancer stem cells and potential therapeutic approaches
  publication-title: Essays Biochem
  doi: 10.1042/EBC20220001
– volume: 42
  start-page: 315
  year: 2020
  ident: 2023011615070897700_bib15
  article-title: Towards new TB vaccines
  publication-title: Semin Immunopathol
  doi: 10.1007/s00281-020-00794-0
– volume: 28
  start-page: 875
  year: 1998
  ident: 2023011615070897700_bib21
  article-title: Nucleoside diphosphate kinase: role in bacterial growth, virulence, cell signalling and polysaccharide synthesis
  publication-title: Mol Microbiol
  doi: 10.1046/j.1365-2958.1998.00846.x
– volume: 13
  start-page: 3072
  year: 2022
  ident: 2023011615070897700_bib68
  article-title: Macrophages disseminate pathogen associated molecular patterns through the direct extracellular release of the soluble content of their phagolysosomes
  publication-title: Nat Commun
  doi: 10.1038/s41467-022-30654-4
– volume: 14
  start-page: e0224239
  year: 2019
  ident: 2023011615070897700_bib176
  article-title: Lipoarabinomannan from Mycobacterium indicus pranii shows immunostimulatory activity and induces autophagy in macrophages
  publication-title: PLoS ONE
  doi: 10.1371/journal.pone.0224239
– volume: 166
  start-page: 1065
  year: 2016
  ident: 2023011615070897700_bib66
  article-title: Phagocytosis: the legacy of Metchnikoff
  publication-title: Cell
  doi: 10.1016/j.cell.2016.08.017
– volume: 105
  start-page: 3980
  year: 2008
  ident: 2023011615070897700_bib144
  article-title: Leishmania requires Rab7-mediated degradation of endocytosed hemoglobin for their growth
  publication-title: Proc Natl Acad Sci
  doi: 10.1073/pnas.0800404105
– volume: 67
  start-page: 4055
  year: 1999
  ident: 2023011615070897700_bib130
  article-title: Activation of phosphotyrosine phosphatase activity attenuates mitogen-activated protein kinase signaling and inhibits c-FOS and nitric oxide synthase expression in macrophages infected with Leishmania donovani
  publication-title: Infect Immun
  doi: 10.1128/IAI.67.8.4055-4063.1999
– volume: 16
  start-page: 1068
  year: 2014
  ident: 2023011615070897700_bib155
  article-title: Listeria monocytogenes antagonizes the human gtpase Cdc42 to promote bacterial spread
  publication-title: Cell Microbiol
  doi: 10.1111/cmi.12260
– volume: 13
  start-page: 272
  year: 2009
  ident: 2023011615070897700_bib197
  article-title: The therapeutic potential of phosphatase inhibitors
  publication-title: Curr Opin Chem Biol
  doi: 10.1016/j.cbpa.2009.03.021
– volume: 31
  start-page: 107746
  year: 2020
  ident: 2023011615070897700_bib152
  article-title: Tlr7 sensing by neutrophils is critical for the control of cutaneous leishmaniasis
  publication-title: Cell Rep
  doi: 10.1016/j.celrep.2020.107746
– volume: 13
  start-page: e1006459
  year: 2017
  ident: 2023011615070897700_bib194
  article-title: Leishmania donovani resides in modified early endosomes by upregulating RAB5a expression via the downregulation of miR-494
  publication-title: PLoS Pathog
  doi: 10.1371/journal.ppat.1006459
– volume: 27
  start-page: 75
  year: 2015
  ident: 2023011615070897700_bib167
  article-title: PRR-signaling pathways: learning from microbial tactics
  publication-title: Semin Immunol
  doi: 10.1016/j.smim.2015.03.009
– start-page: 1
  year: 2022
  ident: 2023011615070897700_bib209
  article-title: Chloroquine treatment induces secretion of autophagy-related proteins and inclusion of Atg8-family proteins in distinct extracellular vesicle populations
  publication-title: Autophagy
  doi: 10.1080/15548627.2022.2153569
– volume: 223
  start-page: 854
  year: 2021
  ident: 2023011615070897700_bib219
  article-title: Signaling lymphocytic activation molecule family-7 alleviates corneal inflammation by promoting M2 polarization
  publication-title: J Infect Dis
  doi: 10.1093/infdis/jiaa445
– volume: 2017
  start-page: 5103803
  year: 2017
  ident: 2023011615070897700_bib211
  article-title: Analysis of differentially expressed proteins in Mycobacterium avium-infected macrophages comparing with Mycobacterium tuberculosis-infected macrophages
  publication-title: Biomed Res Int
– volume: 295
  start-page: 5807
  year: 2020
  ident: 2023011615070897700_bib138
  article-title: Structural insight into the recognition of pathogen-derived phosphoglycolipids by C-type lectin receptor DCAR
  publication-title: J Biol Chem
  doi: 10.1074/jbc.RA120.012491
– volume: 56
  start-page: 427
  year: 2021
  ident: 2023011615070897700_bib119
  article-title: ORF3a of the COVID-19 virus SARS-COV-2 blocks hops complex-mediated assembly of the snare complex required for autolysosome formation
  publication-title: Dev Cell
  doi: 10.1016/j.devcel.2020.12.010
– volume: 2021
  start-page: 8874339
  year: 2021
  ident: 2023011615070897700_bib2
  article-title: Covid-19 and toll-like receptor 4 (TLR4): Sars-CoV-2 may bind and activate TLR4 to increase ACE2 expression, facilitating entry and causing hyperinflammation
  publication-title: Mediat Inflamm
  doi: 10.1155/2021/8874339
– volume: 75
  start-page: 2136
  year: 2007
  ident: 2023011615070897700_bib38
  article-title: Leishmania donovani-induced ceramide as the key mediator of AKT dephosphorylation in murine macrophages: role of protein kinase Czeta and phosphatase
  publication-title: Infect Immun
  doi: 10.1128/IAI.01589-06
– volume: 56
  start-page: 363
  year: 1988
  ident: 2023011615070897700_bib206
  article-title: Roles of CR3 and mannose receptors in the attachment and ingestion of Leishmania donovani by human mononuclear phagocytes
  publication-title: Infect Immun
  doi: 10.1128/iai.56.2.363-369.1988
– volume: 124
  start-page: 767
  year: 2006
  ident: 2023011615070897700_bib51
  article-title: Anti-immunology: evasion of the host immune system by bacterial and viral pathogens
  publication-title: Cell
  doi: 10.1016/j.cell.2006.01.034
– volume: 9
  start-page: e1003499
  year: 2013
  ident: 2023011615070897700_bib183
  article-title: Mycobacterium tuberculosis nucleoside diphosphate kinase inactivates small GTPases leading to evasion of innate immunity
  publication-title: PLoS Pathog
  doi: 10.1371/journal.ppat.1003499
– volume: 126
  start-page: 104257
  year: 2022
  ident: 2023011615070897700_bib213
  article-title: Expression and functional characterization of the mannose receptor (MR) from Nile tilapia (Oreochromis niloticus) in response to bacterial infection
  publication-title: Dev Comp Immunol
  doi: 10.1016/j.dci.2021.104257
– volume: 398
  start-page: 565
  year: 2017
  ident: 2023011615070897700_bib65
  article-title: Mechanisms of action of Rab proteins, key regulators of intracellular vesicular transport
  publication-title: Biol Chem
  doi: 10.1515/hsz-2016-0274
– volume: 12
  start-page: 7115
  year: 2021
  ident: 2023011615070897700_bib4
  article-title: Acetoacetate protects macrophages from lactic acidosis-induced mitochondrial dysfunction by metabolic reprograming
  publication-title: Nat Commun
  doi: 10.1038/s41467-021-27426-x
– volume: 307
  start-page: 66
  year: 2022
  ident: 2023011615070897700_bib3
  article-title: Regulatory strategies limiting endosomal toll-like receptor activation in B cells
  publication-title: Immunol Rev
  doi: 10.1111/imr.13065
– volume: 35
  start-page: 109126
  year: 2021
  ident: 2023011615070897700_bib74
  article-title: Systematic functional analysis of SARS-COV-2 proteins uncovers viral innate immune antagonists and remaining vulnerabilities
  publication-title: Cell Rep
  doi: 10.1016/j.celrep.2021.109126
– volume: 30
  start-page: 115940
  year: 2021
  ident: 2023011615070897700_bib86
  article-title: Discovery of potent glycogen synthase kinase 3/cholinesterase inhibitors with neuroprotection as potential therapeutic agent for Alzheimer's disease
  publication-title: Bioorg Med Chem
  doi: 10.1016/j.bmc.2020.115940
– volume: 117
  start-page: 1994
  year: 2020
  ident: 2023011615070897700_bib106
  article-title: Innate immune receptor NOD2 mediates LGR5(+) intestinal stem cell protection against ROS cytotoxicity via mitophagy stimulation
  publication-title: Proc Nat Acad Sci USA
  doi: 10.1073/pnas.1902788117
– volume: 8
  start-page: e69619
  year: 2013
  ident: 2023011615070897700_bib154
  article-title: Identification of benzimidazole diamides as selective inhibitors of the nucleotide-binding oligomerization domain 2 (NOD2) signaling pathway
  publication-title: PLoS ONE
  doi: 10.1371/journal.pone.0069619
– volume: 40
  start-page: e12521
  year: 2018
  ident: 2023011615070897700_bib148
  article-title: Mannose receptor (MR) and toll-like receptor 2 (TLR2) influence phagosome maturation during Leishmania infection
  publication-title: Parasite Immunol
  doi: 10.1111/pim.12521
– volume: 21
  start-page: e13003
  year: 2019
  ident: 2023011615070897700_bib158
  article-title: Host cell protein LAMP-2 is the receptor for Trypanosoma cruzi surface molecule gp82 that mediates invasion
  publication-title: Cell Microbiol
  doi: 10.1111/cmi.13003
– volume: 40
  start-page: 111282
  year: 2022
  ident: 2023011615070897700_bib126
  article-title: Structural basis for activation of ARF1 at the Golgi complex
  publication-title: Cell Rep
  doi: 10.1016/j.celrep.2022.111282
– volume: 9
  start-page: 1161
  year: 2018
  ident: 2023011615070897700_bib16
  article-title: Mycobacterium tuberculosis catalase inhibits the formation of mast cell extracellular traps
  publication-title: Front Immunol
  doi: 10.3389/fimmu.2018.01161
– volume: 205
  start-page: 125
  year: 2017
  ident: 2023011615070897700_bib214
  article-title: Nucleoside diphosphate kinase (NDK): a pleiotropic effector manipulating bacterial virulence and adaptive responses
  publication-title: Microbiol Res
  doi: 10.1016/j.micres.2017.09.001
– volume: 113 Pt 19
  start-page: 3531
  year: 2000
  ident: 2023011615070897700_bib43
  article-title: Rab5 regulates the kiss and run fusion between phagosomes and endosomes and the acquisition of phagosome leishmanicidal properties in raw 264.7 macrophages
  publication-title: J Cell Sci
  doi: 10.1242/jcs.113.19.3531
– volume: 10
  start-page: 2408
  year: 2008
  ident: 2023011615070897700_bib146
  article-title: Mycobacterial manipulation of vacuolar sorting
  publication-title: Cell Microbiol
  doi: 10.1111/j.1462-5822.2008.01239.x
– volume: 44
  start-page: 463
  year: 2016
  ident: 2023011615070897700_bib67
  article-title: Phagocytosis: an immunobiologic process
  publication-title: Immunity
  doi: 10.1016/j.immuni.2016.02.026
– volume: 68
  start-page: 15
  year: 2021
  ident: 2023011615070897700_bib69
  article-title: NDK/NME proteins: a host-pathogen interface perspective towards therapeutics
  publication-title: Curr Genet
  doi: 10.1007/s00294-021-01198-9
– volume: 26
  start-page: 313
  year: 2007
  ident: 2023011615070897700_bib80
  article-title: Lamp proteins are required for fusion of lysosomes with phagosomes
  publication-title: EMBO J
  doi: 10.1038/sj.emboj.7601511
– volume: 157
  start-page: 3559
  year: 1996
  ident: 2023011615070897700_bib195
  article-title: Natural resistance to intracellular infections: Nramp1 encodes a membrane phosphoglycoprotein absent in macrophages from susceptible (Nramp1 D169) mouse strains
  publication-title: J Immunol
  doi: 10.4049/jimmunol.157.8.3559
– volume: 244
  start-page: 10
  year: 2006
  ident: 2023011615070897700_bib147
  article-title: P2x(7) purinergic receptors and extracellular ATP mediate apoptosis of human monocytes/macrophages infected with Mycobacterium tuberculosis reducing the intracellular bacterial viability
  publication-title: Cell Immunol
  doi: 10.1016/j.cellimm.2007.02.001
– volume: 6
  start-page: 946
  year: 2015
  ident: 2023011615070897700_bib63
  article-title: Downregulation of host tryptophan-aspartate containing coat (TACO) gene restricts the entry and survival of Leishmania donovani in human macrophage model
  publication-title: Front Microbiol
  doi: 10.3389/fmicb.2015.00946
– volume: 1770
  start-page: 649
  year: 2007
  ident: 2023011615070897700_bib40
  article-title: Differential expression of NF-KappaB in Mycobacteria infected Thp-1 affects apoptosis
  publication-title: Biochim Biophys Acta
  doi: 10.1016/j.bbagen.2006.11.016
– volume: 4
  start-page: 180
  year: 2014
  ident: 2023011615070897700_bib123
  article-title: The complexity of Rab5 to Rab7 transition guarantees specificity of pathogen subversion mechanisms
  publication-title: Front Cell Infect Microbiol
  doi: 10.3389/fcimb.2014.00180
– volume: 130
  start-page: 37
  year: 2007
  ident: 2023011615070897700_bib85
  article-title: Survival of mycobacteria in macrophages is mediated by coronin 1-dependent activation of calcineurin
  publication-title: Cell
  doi: 10.1016/j.cell.2007.04.043
– volume: 161
  start-page: 1306
  year: 2015
  ident: 2023011615070897700_bib120
  article-title: A TRP channel senses lysosome neutralization by pathogens to trigger their expulsion
  publication-title: Cell
  doi: 10.1016/j.cell.2015.05.009
– volume: 218
  start-page: 1104
  year: 2013
  ident: 2023011615070897700_bib162
  article-title: Implication of purinergic P2×7 receptor in M. tuberculosis infection and host interaction mechanisms: a mouse model study
  publication-title: Immunobiology
  doi: 10.1016/j.imbio.2013.03.003
– volume: 4
  start-page: 88
  year: 2018
  ident: 2023011615070897700_bib165
  article-title: Combating intracellular pathogens with repurposed host-targeted drugs
  publication-title: ACS Infect Dis
  doi: 10.1021/acsinfecdis.7b00268
– volume: 124
  start-page: 1006
  year: 2016
  ident: 2023011615070897700_bib108
  article-title: Discovery of oral-available resveratrol-caffeic acid based hybrids inhibiting acetylated and phosphorylated STAT3 protein
  publication-title: Eur J Med Chem
  doi: 10.1016/j.ejmech.2016.10.028
– volume: 13
  start-page: e0206459
  year: 2018
  ident: 2023011615070897700_bib125
  article-title: Mycobacterium tuberculosis host cell interaction: role of latency associated protein ACR-1 in differential modulation of macrophages
  publication-title: PLoS ONE
  doi: 10.1371/journal.pone.0206459
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Snippet Abstract The intracellular viral, bacterial, or parasitic pathogens evade the host immune challenges to propagate and cause fatal diseases. The microbes...
The intracellular viral, bacterial, or parasitic pathogens evade the host immune challenges to propagate and cause fatal diseases. The microbes overpower host...
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SubjectTerms Acidification
Agonists
Antigen presentation
Antigens
Apoptosis
Autophagy
BCG
BCG vaccines
Communicable diseases
Communicable Diseases - metabolism
Cytosol
Development and progression
Drug development
Health aspects
Humans
Immune Evasion
Immune system
Infectious diseases
Inflammation
Inflammatory response
Intracellular
Lymphocytes T
Macrophages - metabolism
Macrophages - microbiology
Parasitic diseases
Pathogenic microorganisms
Pathogens
Phagocytosis
Phagolysosomes
Phagosomes
Phagosomes - metabolism
Phagosomes - microbiology
Reactive oxygen species
Therapeutic applications
Therapeutic targets
Zooming
Title Zooming in on common immune evasion mechanisms of pathogens in phagolysosomes: potential broad-spectrum therapeutic targets against infectious diseases
URI https://www.ncbi.nlm.nih.gov/pubmed/36309472
https://www.proquest.com/docview/2823849094
https://www.proquest.com/docview/2730314921
Volume 47
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