Has Highly Active Antiretroviral Therapy Increased the Time to Seroreversion in HIV Exposed but Uninfected Children?

• Published in: Clinical infectious diseases Vol. 55; no. 9; pp. 1255 - 1261
• Main Authors: Gutierrez, Mavel, Ludwig, David A., Khan, Safia S., Chaparro, Aida A., Rivera, Delia M., Cotter, Amanda M., Scott, Gwendolyn B.
• Format: Journal Article
• Language: English
• Published: Oxford Oxford University Press 01.11.2012
• Subjects: AIDS; Anti-HIV Agents - administration & dosage; Antibiotics. Antiinfectious agents. Antiparasitic agents; Antibodies; Antiretroviral drugs; Antiretroviral Therapy, Highly Active - methods; Antiviral agents; Biological and medical sciences; Chemoprevention - methods; Child, Preschool; Children; Disease prevention; Drug therapy; Female; Highly active antiretroviral therapy; HIV; HIV Antibodies - blood; HIV infections; HIV Infections - prevention & control; HIV Seropositivity; HIV/AIDS; Human immunodeficiency virus; Human viral diseases; Humans; Immunodeficiencies; Immunodeficiencies. Immunoglobulinopathies; Immunopathology; Infant; Infant, Newborn; Infants; Infections; Infectious Disease Transmission, Vertical - prevention & control; Infectious diseases; Male; Maternal & child health; Medical sciences; Pharmacology. Drug treatments; Pregnancy; Protease inhibitors; Rates of change; Retrospective Studies; Time Factors; United States; Viral diseases; Viral diseases of the lymphoid tissue and the blood. Aids; Viral load; United States; Human; Immunopathology; Retroviridae; AIDS; Immune deficiency; Lentivirus; Infection; Virus; Chemotherapy; Treatment; Viral disease; Antiviral; Human immunodeficiency virus; Child

Background. Since the introduction of highly active antiretroviral therapy (HAART) for prevention of mother-to-child transmission of human immunodeficiency virus (HIV) in pregnancy in the United States, the time of seroreversion in infants born to HIV-infected mothers has not been documented. The ob...