Genetic Analysis Reveals That C₁₉-GA 2-Oxidation Is a Major Gibberellin Inactivation Pathway in Arabidopsis

• Published in: The Plant cell Vol. 20; no. 9; pp. 2420 - 2436
• Main Authors: Rieu, Ivo, Eriksson, Sven, Powers, Stephen J, Gong, Fan, Griffiths, Jayne, Woolley, Lindsey, Benlloch, Reyes, Nilsson, Ove, Thomas, Stephen G, Hedden, Peter, Phillips, Andrew L
• Format: Journal Article
• Language: English
• Published: England American Society of Plant Biologists 01.09.2008
• Subjects: Arabidopsis - genetics; Arabidopsis - growth & development; Arabidopsis - metabolism; Arabidopsis Proteins - genetics; Arabidopsis Proteins - metabolism; Arabidopsis thaliana; Biosynthesis; developmental stages; Flowering; flowers; Flowers - genetics; Flowers - growth & development; Flowers - metabolism; Fruit - genetics; Fruit - growth & development; Fruit - metabolism; Gene Expression Regulation, Plant; Genes; genetic techniques and protocols; Germination - genetics; Germination - physiology; Gibberellins; Gibberellins - metabolism; hormones; Hypocotyl - genetics; Hypocotyl - growth & development; Hypocotyl - metabolism; Inflorescences; Internodes; Models, Genetic; Oxidation-Reduction; Phenotypes; Plant cells; plant hormones; Plant Roots - genetics; Plant Roots - growth & development; Plant Roots - metabolism; Plant Stems - genetics; Plant Stems - growth & development; Plant Stems - metabolism; Plants; Plants, Genetically Modified - genetics; Plants, Genetically Modified - growth & development; Plants, Genetically Modified - metabolism; seed germination; Seeds; Seeds - genetics; Seeds - growth & development; Seeds - metabolism; shoots; Signal Transduction - genetics; Signal Transduction - physiology; stem elongation

Bioactive hormone concentrations are regulated both at the level of hormone synthesis and through controlled inactivation. Based on the ubiquitous presence of 2β-hydroxylated gibberellins (GAs), a major inactivating pathway for the plant hormone GA seems to be via GA 2-oxidation. In this study, we u...